DE69702880D1 - Taxol enthaltende Zusammensetzung zur Verwendung in der Organkonservierung und als kardioplegisches Mittel - Google Patents

Taxol enthaltende Zusammensetzung zur Verwendung in der Organkonservierung und als kardioplegisches Mittel

Info

Publication number
DE69702880D1
DE69702880D1 DE69702880T DE69702880T DE69702880D1 DE 69702880 D1 DE69702880 D1 DE 69702880D1 DE 69702880 T DE69702880 T DE 69702880T DE 69702880 T DE69702880 T DE 69702880T DE 69702880 D1 DE69702880 D1 DE 69702880D1
Authority
DE
Germany
Prior art keywords
composition containing
organ preservation
containing taxol
cardioplegic agent
taxol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69702880T
Other languages
English (en)
Other versions
DE69702880T2 (de
Inventor
James H Southard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of DE69702880D1 publication Critical patent/DE69702880D1/de
Application granted granted Critical
Publication of DE69702880T2 publication Critical patent/DE69702880T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69702880T 1996-05-07 1997-05-06 Taxol enthaltende Zusammensetzung zur Verwendung in der Organkonservierung und als kardioplegisches Mittel Expired - Fee Related DE69702880T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/646,055 US5696152A (en) 1996-05-07 1996-05-07 Taxol composition for use as organ preservation and cardioplegic agents

Publications (2)

Publication Number Publication Date
DE69702880D1 true DE69702880D1 (de) 2000-09-28
DE69702880T2 DE69702880T2 (de) 2001-03-01

Family

ID=24591558

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69702880T Expired - Fee Related DE69702880T2 (de) 1996-05-07 1997-05-06 Taxol enthaltende Zusammensetzung zur Verwendung in der Organkonservierung und als kardioplegisches Mittel

Country Status (5)

Country Link
US (1) US5696152A (de)
EP (1) EP0806140B1 (de)
JP (1) JP3969785B2 (de)
AT (1) ATE195626T1 (de)
DE (1) DE69702880T2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6680305B1 (en) * 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
US6365385B1 (en) 1999-03-22 2002-04-02 Duke University Methods of culturing and encapsulating pancreatic islet cells
US6303355B1 (en) 1999-03-22 2001-10-16 Duke University Method of culturing, cryopreserving and encapsulating pancreatic islet cells
FR2793651B1 (fr) * 1999-05-18 2003-05-16 Cair L G L Solution aqueuse de conservation de tissus et d'organes
DE10020507A1 (de) * 2000-04-26 2001-11-08 Wolfgang Thasler Lösung zur Konservierung menschlicher Leberzellen, konservierte menschliche Leberzelle, ihre Herstellung und Verwendung
AU2001279073B2 (en) * 2000-07-28 2006-08-24 Christopher J. Murphy Transplant media
GB0028414D0 (en) * 2000-11-22 2001-01-03 Univ Leeds Flush preservation solution
DE10209822A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
KR101174510B1 (ko) 2002-09-11 2012-08-16 프레제니우스 카비 도이치란트 게엠베하 하이드록시알킬전분화 폴리펩티드, 특히 하이드록시알킬전분화 에리트로포이에틴
EP1475434A1 (de) 2003-05-09 2004-11-10 Oncoscience AG Verfahren zur Lagerung von Tumorzellen
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
EP2336192A1 (de) 2004-03-11 2011-06-22 Fresenius Kabi Deutschland GmbH Hydroxyalkylstärke-Protein-Konjugate, durch reduktive Aminierung hergestellt.
WO2006008270A1 (de) * 2004-07-22 2006-01-26 Thiomatrix Forschungs- Und Beratungs Gmbh Verwendung von thiolgruppen-hältigen verbindungen als efflux-pumpen-hemmer
US20080161423A1 (en) * 2005-03-04 2008-07-03 Atsushi Kudo Organ Function Maintaining or Amelorating Solution
WO2006093314A1 (ja) * 2005-03-04 2006-09-08 National University Corporation, Tokyo Medical And Dental University 臓器機能維持改善液
GB0612877D0 (en) * 2006-06-29 2006-08-09 Univ Edinburgh Organ preservation solution
EP2070950A1 (de) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkylstärkederivate und deren Herstellungsverfahren
US20210392873A1 (en) 2011-03-15 2021-12-23 Paragonix Technologies, Inc. System for hypothermic transport of samples
US12096765B1 (en) 2011-03-15 2024-09-24 Paragonix Technologies, Inc. System for hypothermic transport of samples
US11178866B2 (en) 2011-03-15 2021-11-23 Paragonix Technologies, Inc. System for hypothermic transport of samples
US9253976B2 (en) 2011-03-15 2016-02-09 Paragonix Technologies, Inc. Methods and devices for preserving tissues
US8835158B2 (en) 2011-03-15 2014-09-16 Paragonix Technologics, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
US9867368B2 (en) 2011-03-15 2018-01-16 Paragonix Technologies, Inc. System for hypothermic transport of samples
US9426979B2 (en) 2011-03-15 2016-08-30 Paragonix Technologies, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
US8828710B2 (en) 2011-03-15 2014-09-09 Paragonix Technologies, Inc. System for hypothermic transport of samples
US8785116B2 (en) 2012-08-10 2014-07-22 Paragonix Technologies, Inc. Methods for evaluating the suitability of an organ for transplant
US9560846B2 (en) 2012-08-10 2017-02-07 Paragonix Technologies, Inc. System for hypothermic transport of biological samples
US10440947B2 (en) 2013-11-15 2019-10-15 Inserm (Institut National De La Sante Et De La Recherche Medicale) Aqueous solution for preserving an organ and uses during hypothermic ischemia
US11166452B2 (en) 2017-06-07 2021-11-09 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
US11632951B2 (en) 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
USD1031028S1 (en) 2022-09-08 2024-06-11 Paragonix Technologies, Inc. Tissue suspension adaptor

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879283A (en) * 1985-10-03 1989-11-07 Wisconsin Alumni Research Foundation Solution for the preservation of organs
US4798824A (en) * 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
WO1991009520A1 (en) * 1989-12-21 1991-07-11 The Regents Of The University Of California Novel and improved technology for preservation of organs for transplantation
US5145771A (en) * 1990-04-12 1992-09-08 The University Of North Carolina At Chapel Hill Rinse solution for organs and tissues
US5407683A (en) * 1990-06-01 1995-04-18 Research Corporation Technologies, Inc. Pharmaceutical solutions and emulsions containing taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5407793A (en) * 1991-10-18 1995-04-18 University Of Pittsburgh Of The Commonwealth System Of Higher Education An aqueous heart preservation and cardioplegia solution
US5344775A (en) * 1991-11-15 1994-09-06 Escagenetics Corporation Synthesis of taxanes in culture using pseudocalluscells
US5451392A (en) * 1992-03-03 1995-09-19 The Research And Development Institute At Montana State University Production of taxol
DK0706373T3 (da) * 1992-03-23 2000-09-18 Univ Georgetown Liposomindkapslet taxol og en fremgangsmåde til anvendelse heraf
US5370989A (en) * 1992-04-03 1994-12-06 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
WO1994000008A1 (en) * 1992-06-26 1994-01-06 Torii & Co., Ltd. Organ preserving fluid
WO1994005282A1 (en) * 1992-09-04 1994-03-17 The Scripps Research Institute Water soluble taxol derivatives
WO1994012172A1 (en) * 1992-12-02 1994-06-09 Thomas Jefferson University Methods of killing protozoal parasites
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
DE69430805T2 (de) * 1993-08-12 2003-02-13 University Of North Carolina At Chapel Hill, Chapel Hill Spüllösung für organe und gewebe
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
US5428039A (en) * 1994-02-20 1995-06-27 The Center For Innovative Technology Method for electively achieving reversible hyperpolarized cardiac arrest

Also Published As

Publication number Publication date
JP3969785B2 (ja) 2007-09-05
JPH1045502A (ja) 1998-02-17
ATE195626T1 (de) 2000-09-15
EP0806140A1 (de) 1997-11-12
EP0806140B1 (de) 2000-08-23
DE69702880T2 (de) 2001-03-01
US5696152A (en) 1997-12-09

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Legal Events

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8339 Ceased/non-payment of the annual fee