DE69637730D1 - Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation - Google Patents

Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation

Info

Publication number
DE69637730D1
DE69637730D1 DE69637730T DE69637730T DE69637730D1 DE 69637730 D1 DE69637730 D1 DE 69637730D1 DE 69637730 T DE69637730 T DE 69637730T DE 69637730 T DE69637730 T DE 69637730T DE 69637730 D1 DE69637730 D1 DE 69637730D1
Authority
DE
Germany
Prior art keywords
transplantation
preconditioning
mobilates
vito
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69637730T
Other languages
English (en)
Inventor
Jacques P Tremblay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Laval
Original Assignee
Universite Laval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Laval filed Critical Universite Laval
Application granted granted Critical
Publication of DE69637730D1 publication Critical patent/DE69637730D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69637730T 1995-03-16 1996-03-15 Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation Expired - Lifetime DE69637730D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/404,888 US5833978A (en) 1995-03-16 1995-03-16 Method of in vitro preconditioning healthy donor's myoblasts before transplantation thereof in compatible patients suffering of recessive myopathies like muscular dystrophy, for improving transplantation success
PCT/CA1996/000158 WO1996028541A1 (en) 1995-03-16 1996-03-15 Method for in vitro preconditioning of myoblasts before transplantation

Publications (1)

Publication Number Publication Date
DE69637730D1 true DE69637730D1 (de) 2008-12-11

Family

ID=23601451

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69637730T Expired - Lifetime DE69637730D1 (de) 1995-03-16 1996-03-15 Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation

Country Status (7)

Country Link
US (2) US5833978A (de)
EP (1) EP0815205B1 (de)
AT (1) ATE412734T1 (de)
AU (1) AU4934496A (de)
CA (1) CA2215244C (de)
DE (1) DE69637730D1 (de)
WO (1) WO1996028541A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410320B1 (en) 1992-03-02 2002-06-25 The University Of Michigan Method and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules
US20020164313A1 (en) * 1995-03-16 2002-11-07 Tremblay Jacques P. Compositions comprising preconditioned myoblasts having enhanced fusion properties
US6150164A (en) * 1996-09-30 2000-11-21 The Regents Of The University Of Michigan Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
US20020012657A1 (en) * 1996-10-18 2002-01-31 Jacques P. Tremblay Method for in vitro preconditioning of myoblasts before transplantation
CA2275436A1 (en) * 1996-12-20 1998-07-02 Creative Biomolecules, Inc. Treatment of mammalian myocardium with morphogen locally, or with morphogenically-treated myogenic precursor cells
WO1999030730A1 (en) * 1997-12-15 1999-06-24 Universite Laval Methods and compositions for improving the success of cell transplantation in a host
US20030129750A1 (en) * 1998-02-05 2003-07-10 Yitzhack Schwartz Homing of donor cells to a target zone in tissue using active therapeutics or substances
US20030113303A1 (en) * 1998-02-05 2003-06-19 Yitzhack Schwartz Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances
US6866842B1 (en) * 1998-05-01 2005-03-15 University Of Pittsburgh Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
US7115417B1 (en) 1998-05-01 2006-10-03 Chancellor Michael B Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof
US6284242B1 (en) * 1999-04-16 2001-09-04 Regents Of The University Of Michigan Method for enhancing myoblast migration and invasion in the context of gene therapy
CA2386559A1 (en) * 1999-09-14 2001-03-22 The Children's Medical Center Corporation Isolation of muscle-derived stem cells and uses therefor
JP5684963B2 (ja) * 2000-04-14 2015-03-18 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 筋肉由来前駆細胞、その組成物、および治療法を使用した軟部組織および骨の増大および肥厚
US6538010B1 (en) * 2000-11-08 2003-03-25 Research Triangle Institute Compounds and methods for promoting smoking cessation
CA2438904C (en) * 2001-02-23 2012-09-04 The University Of Pittsburgh Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
US7332330B2 (en) 2001-09-11 2008-02-19 Renamed Biologics, Inc. Device for maintaining vascularization near an implant
US7442546B2 (en) * 2002-03-15 2008-10-28 The Regents Of The University Of Michigan Method of modulating inflammatory response
EP1497410A4 (de) * 2002-04-01 2005-05-25 Peter K Law Zelltransplantation zur herzregenerierung
EP2289526B1 (de) * 2003-04-25 2014-06-11 The University of Pittsburgh Muskeln abstammande zellen zur wiederherstellung und regenerierung nach nervenschädigung
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7828711B2 (en) 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US8874204B2 (en) 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US20060263338A1 (en) * 2005-03-04 2006-11-23 Jacoby Douglas B Catheter-based delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts
JP5425641B2 (ja) 2007-01-11 2014-02-26 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 尿路病状の処置のための筋由来細胞ならびにその作製および使用の方法
CA2734858C (en) * 2008-08-18 2019-01-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof
US20100233138A1 (en) * 2008-11-07 2010-09-16 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Vocal Cord Augmentation Utilizing Muscle-Derived Progenitor Compositions, and Treatments Thereof
US10273520B2 (en) 2013-04-03 2019-04-30 Wan Keung Raymond Wong Means and methods for hyper-production of authentic human basic fibroblast growth factor in Escherichia coli
JP6404901B2 (ja) * 2013-04-03 2018-10-17 ウォン，ワン ケウン レイモンドＷＯＮＧ， Ｗａｎ Ｋｅｕｎｇ Ｒａｙｍｏｎｄ 大腸菌の細胞質および／または培地中の真正ヒト上皮成長因子および／または塩基性線維芽細胞成長因子の発現の手段および方法
EP3057599A4 (de) * 2013-10-17 2017-04-19 University of Maryland, Baltimore Verfahren zur erzeugung von reifen menschlichen muskelfasern
JP2019513010A (ja) * 2016-03-04 2019-05-23 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー プロスタグランジンｅ２を用いる、筋再生のための組成物および方法
US9918994B2 (en) 2016-03-04 2018-03-20 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
WO2018227138A1 (en) 2017-06-09 2018-12-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing or treating muscle conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130141A (en) * 1988-05-24 1992-07-14 Law Peter K Compositions for and methods of treating muscle degeneration and weakness
US5143842A (en) * 1988-11-01 1992-09-01 The University Of Colorado Foundation, Inc. Media for normal human muscle satellite cells
WO1991007992A1 (en) * 1989-11-24 1991-06-13 Monash University Proliferative action of leukaemia inhibitory factor on satellite cells

Also Published As

Publication number Publication date
EP0815205B1 (de) 2008-10-29
CA2215244A1 (en) 1996-09-19
EP0815205A1 (de) 1998-01-07
ATE412734T1 (de) 2008-11-15
AU4934496A (en) 1996-10-02
CA2215244C (en) 2009-12-22
WO1996028541A1 (en) 1996-09-19
US20010051148A1 (en) 2001-12-13
US5833978A (en) 1998-11-10

Similar Documents

Publication Publication Date Title
DE69637730D1 (de) Verfahren zur in vito vorbehandlung von myoblasten vor deren transplantation
TW349941B (en) Substituted N-heteroaroylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them
WO2000052054A3 (en) ANTIBODIES FOR THE TREATMENT AND DIAGNOSIS OF CANCER
BG102202A (en) Enantiomer and ipratropiumbromide with extended effect
WO1999064059A3 (en) Use of secretin for the treatment of autism and other neurological, behavioral and immunological disorders
GEP20002180B (en) Composition and Methods for Stimulating Megakaryocyte Growth and Differentiation
HK1031197A1 (en) Osmotic dosage form comprising first and second coats
WO1996025947A3 (en) Induction of e-selectin for targetting therapeutic agents
AU6628496A (en) Polyether block copolymer micellar compositions for targeting biological agents
MX9803992A (es) Metodos para incrementar la masa de tejido muscular usando composiciones de la proteina ob.
PT998287E (pt) Utilizacao de levobupivacaina
GR1000719B (el) Μεθοδος παρασκευης της (s)-α-εθυλ-2-οξο-1-πυρρολιδινοακεταμιδης.
WO1992018536A3 (en) Method for detecting an localizing tissues having neurokinine 1 receptors
HUP9903679A2 (hu) Olanzapin alkalmazása bipoláris zavar kezelésére szolgáló gyógyszerkészítmények előállítására
AU1200488A (en) Protein c inhibitor (pci) as pharmaceutical and in vitro diagnostic aid, a process for the preparation of a pharmaceutical or diagnostic aid of this type, and an agent containing pci
WO1998011919A3 (en) Polyethyleneglycol conjugated nanoerythrosomes, method of making same and use thereof
EP0904094A4 (de) Behandlung von knochenleiden mit adrenomedullin
TW374085B (en) Novel piperidine derivatives, their preparation, pharmaceutical formulation and medical use
EA199900006A1 (ru) Препарат и способ для лечения застоной сердечной недостаточности
IL126158A0 (en) Method for treating substance abuse
UA42749C2 (uk) N,n-діетил-8,8-дипропіл-2-азаспіро[4,5]декан-2-пропанамін дималеат, фармацевтична композиція, спосіб лікування
EP0301449A3 (en) Enantiomers of propafenone-containing therapeutic agents
EP0569531A4 (de) Stabilisierte antikörperfragmente.
UA30659A (uk) Спосіб купіровання опіатної залежності
UA10754A (uk) Спосіб лікуваhhя артеріальhих гіпертеhзій різhого геhезу

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R079 Amendment of ipc main class

Ref document number: 815205

Country of ref document: EP

Free format text: PREVIOUS MAIN CLASS: C12N0005060000

Ipc: C12N0005077000