DE69633344D1 - Kalibrierverfahren und vorrichtung fur durchflusscytometer - Google Patents
Kalibrierverfahren und vorrichtung fur durchflusscytometerInfo
- Publication number
- DE69633344D1 DE69633344D1 DE69633344T DE69633344T DE69633344D1 DE 69633344 D1 DE69633344 D1 DE 69633344D1 DE 69633344 T DE69633344 T DE 69633344T DE 69633344 T DE69633344 T DE 69633344T DE 69633344 D1 DE69633344 D1 DE 69633344D1
- Authority
- DE
- Germany
- Prior art keywords
- calibration method
- flow cytometer
- cytometer
- calibration
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1012—Calibrating particle analysers; References therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J2003/2866—Markers; Calibrating of scan
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/579,186 US5837547A (en) | 1995-12-27 | 1995-12-27 | Flow cytometer calibration method |
US579186 | 1995-12-27 | ||
PCT/US1996/020608 WO1997024613A1 (en) | 1995-12-27 | 1996-12-24 | Flow cytometer calibration method and kit |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69633344D1 true DE69633344D1 (de) | 2004-10-14 |
DE69633344T2 DE69633344T2 (de) | 2005-02-17 |
Family
ID=24315919
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69633344T Expired - Lifetime DE69633344T2 (de) | 1995-12-27 | 1996-12-24 | Kalibrierverfahren und vorrichtung fur durchflusscytometer |
Country Status (5)
Country | Link |
---|---|
US (1) | US5837547A (de) |
EP (1) | EP0870195B1 (de) |
AU (1) | AU1567197A (de) |
DE (1) | DE69633344T2 (de) |
WO (1) | WO1997024613A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6074879A (en) | 1997-06-23 | 2000-06-13 | Bayer Corporation | Synthetic polymer particles for use as standards and calibrators in flow cytometry |
US6696304B1 (en) * | 1999-02-24 | 2004-02-24 | Luminex Corporation | Particulate solid phase immobilized protein quantitation |
AU6779300A (en) * | 1999-08-17 | 2001-03-13 | Luminex Corporation | System and method for eliminating the effects of doublets and carryover |
US6696265B1 (en) * | 1999-08-17 | 2004-02-24 | Luminex Corporation | System and method for eliminating the effects of doublets and carryover |
US20040157277A1 (en) * | 2002-03-08 | 2004-08-12 | Clancy Robert Llewellyn | Methods for predicting and/or diagnosing the risk of gastric cancer |
US7242474B2 (en) * | 2004-07-27 | 2007-07-10 | Cox James A | Cytometer having fluid core stream position control |
US7630063B2 (en) * | 2000-08-02 | 2009-12-08 | Honeywell International Inc. | Miniaturized cytometer for detecting multiple species in a sample |
US8071051B2 (en) | 2004-05-14 | 2011-12-06 | Honeywell International Inc. | Portable sample analyzer cartridge |
US8329118B2 (en) | 2004-09-02 | 2012-12-11 | Honeywell International Inc. | Method and apparatus for determining one or more operating parameters for a microfluidic circuit |
US7130046B2 (en) * | 2004-09-27 | 2006-10-31 | Honeywell International Inc. | Data frame selection for cytometer analysis |
US7016022B2 (en) * | 2000-08-02 | 2006-03-21 | Honeywell International Inc. | Dual use detectors for flow cytometry |
US7277166B2 (en) | 2000-08-02 | 2007-10-02 | Honeywell International Inc. | Cytometer analysis cartridge optical configuration |
US20030119203A1 (en) | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
US7432105B2 (en) * | 2002-08-27 | 2008-10-07 | Kimberly-Clark Worldwide, Inc. | Self-calibration system for a magnetic binding assay |
US7781172B2 (en) | 2003-11-21 | 2010-08-24 | Kimberly-Clark Worldwide, Inc. | Method for extending the dynamic detection range of assay devices |
US7247500B2 (en) | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
US20040132092A1 (en) * | 2003-01-03 | 2004-07-08 | Stetson Christopher M. | Determining the density of functional moieties on polymer reagents |
US7713748B2 (en) | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
WO2005100539A2 (en) * | 2004-04-07 | 2005-10-27 | Levine, Robert, A. | Disposable chamber for analyzing biologic fluids |
US7109036B2 (en) * | 2004-05-13 | 2006-09-19 | Beckman Coulter, Inc. | Hematology reference control containing an immature granulocyte component |
US8323564B2 (en) | 2004-05-14 | 2012-12-04 | Honeywell International Inc. | Portable sample analyzer system |
JP4746285B2 (ja) * | 2004-06-30 | 2011-08-10 | シスメックス株式会社 | 血液分析装置、分析プログラム、分画領域設定方法 |
US7612871B2 (en) * | 2004-09-01 | 2009-11-03 | Honeywell International Inc | Frequency-multiplexed detection of multiple wavelength light for flow cytometry |
US7630075B2 (en) | 2004-09-27 | 2009-12-08 | Honeywell International Inc. | Circular polarization illumination based analyzer system |
US7731901B2 (en) * | 2005-10-19 | 2010-06-08 | Abbott Laboratories | Apparatus and method for performing counts within a biologic fluid sample |
US7806604B2 (en) * | 2005-10-20 | 2010-10-05 | Honeywell International Inc. | Face detection and tracking in a wide field of view |
EP1963866B1 (de) * | 2005-12-22 | 2018-05-16 | Honeywell International Inc. | Hematologischer analysator mit entfernbarer kartusche |
WO2007075922A2 (en) | 2005-12-22 | 2007-07-05 | Honeywell International Inc. | Portable sample analyzer cartridge |
JP5431732B2 (ja) | 2005-12-29 | 2014-03-05 | ハネウェル・インターナショナル・インコーポレーテッド | マイクロ流体フォーマットにおけるアッセイ実装 |
US20080129961A1 (en) * | 2006-11-30 | 2008-06-05 | Abraham Schwartz | Method and apparatus for measuring quantity of a fluorochrome in a biological environment |
US8187885B2 (en) * | 2009-05-07 | 2012-05-29 | Nodality, Inc. | Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument |
US8663583B2 (en) | 2011-12-27 | 2014-03-04 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
US8741235B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Two step sample loading of a fluid analysis cartridge |
US8741233B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
US8741234B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
GB2499796B (en) * | 2012-02-28 | 2016-06-15 | Ojk Consulting Ltd | Method and system for calibrating a flow cytometer |
EP3514543B1 (de) * | 2013-11-07 | 2021-05-05 | Boston Cell Standards LLC | Quantitative steuerungen und kalibratoren für zelluläre analyten |
EP3688181A4 (de) * | 2017-09-29 | 2021-06-16 | University of Iowa Research Foundation | Zusammensetzungen und verfahren zur detektion von digitalen nukleasen |
CN110554178A (zh) * | 2019-04-23 | 2019-12-10 | 杭州深度生物科技有限公司 | 一种悬浮式液态生物芯片检测方法 |
CN112881269A (zh) * | 2021-02-23 | 2021-06-01 | 浙江正熙生物技术股份有限公司 | 一种流式荧光检测试剂的质量检测方法 |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE790042A (nl) * | 1971-10-14 | 1973-04-13 | Coulter Electronics | Werkwijze voor het classifiseren van deeltjes |
US4035316A (en) * | 1975-11-24 | 1977-07-12 | California Institute Of Technology | Cell specific, variable density, polymer microspheres |
US4170685A (en) * | 1976-03-29 | 1979-10-09 | California Institute Of Technology | Polyvinyl pyridine microspheres |
US4162282A (en) * | 1976-04-22 | 1979-07-24 | Coulter Electronics, Inc. | Method for producing uniform particles |
US4157323A (en) * | 1976-06-09 | 1979-06-05 | California Institute Of Technology | Metal containing polymeric functional microspheres |
US4247434A (en) * | 1978-12-29 | 1981-01-27 | Lovelace Alan M Administrator | Process for preparation of large-particle-size monodisperse |
US4254096A (en) * | 1979-10-04 | 1981-03-03 | Bio-Rad Laboratories, Inc. | Reagent combination for solid phase immunofluorescent assay |
DE3171273D1 (en) * | 1980-12-09 | 1985-08-08 | Toray Industries | Immunoparticles and process for preparing the same |
US4438239A (en) * | 1981-03-30 | 1984-03-20 | California Institute Of Technology | Microsphere coated substrate containing reactive aldehyde groups |
US4499052A (en) * | 1982-08-30 | 1985-02-12 | Becton, Dickinson And Company | Apparatus for distinguishing multiple subpopulations of cells |
DE3238353A1 (de) * | 1982-10-15 | 1984-04-19 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer |
JPS59174742A (ja) * | 1983-03-25 | 1984-10-03 | Agency Of Ind Science & Technol | 微小粒子を区分又は選別する方法及びその装置 |
US4605630A (en) * | 1983-07-27 | 1986-08-12 | Cooper Lipotech Inc. | Large-liposome agglutination reagent and method |
US4699828A (en) * | 1984-04-27 | 1987-10-13 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
US4699826A (en) * | 1984-04-27 | 1987-10-13 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
US4609689A (en) * | 1984-04-27 | 1986-09-02 | Becton, Dickinson And Company | Method of preparing fluorescently labeled microbeads |
US4698262A (en) * | 1984-04-27 | 1987-10-06 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
US4665020A (en) * | 1984-05-30 | 1987-05-12 | United States Department Of Energy | Flow cytometer measurement of binding assays |
US4661913A (en) * | 1984-09-11 | 1987-04-28 | Becton, Dickinson And Company | Apparatus and method for the detection and classification of articles using flow cytometry techniques |
US5314824A (en) * | 1984-12-24 | 1994-05-24 | Caribbean Microparticles Corporation | Method of setting up a flow cytometer |
US5073498A (en) * | 1984-12-24 | 1991-12-17 | Caribbean Microparticles Corporation | Fluorescent alignment microbeads with broad excitation and emission spectra and its use |
US5073497A (en) * | 1989-06-30 | 1991-12-17 | Caribbean Microparticles Corporation | Microbead reference standard and method of adjusting a flow cytometer to obtain reproducible results using the microbeads |
US5089416A (en) * | 1984-12-24 | 1992-02-18 | Caribbean Microparticles Corporation | Method of use of non-fluorescent particles to determine fluorescence threshold of a flow cytometer relative to the autofluorescence of samples |
US4774189A (en) * | 1984-12-24 | 1988-09-27 | Flow Cytometry Standards Corp. | Fluorescent calibration microbeads simulating stained cells |
US4918004A (en) * | 1984-12-24 | 1990-04-17 | Caribbean Microparticles Corporation | Method of calibrating a flow cytometer or fluorescence microscope for quantitating binding antibodies on a selected sample, and microbead calibration kit therefor |
US4767206A (en) * | 1984-12-24 | 1988-08-30 | Flow Cytometry Standards Corporation | Calibration method for flow cytometry using fluorescent microbeads and synthesis thereof |
US5380663A (en) * | 1984-12-24 | 1995-01-10 | Caribbean Microparticles Corporation | Automated system for performance analysis and fluorescence quantitation of samples |
US5093234A (en) * | 1984-12-24 | 1992-03-03 | Caribbean Microparticles Corporation | Method of aligning, compensating, and calibrating a flow cytometer for analysis of samples, and microbead standards kit therefor |
US4828984A (en) * | 1986-04-11 | 1989-05-09 | Flow Cytometry Standards Corporation | Composition, synthesis and use of simulated cells |
US4857451A (en) * | 1984-12-24 | 1989-08-15 | Flow Cytometry Standards Corporation | Method of compensating and calibrating a flow cytometer, and microbead standards kit therefor |
US5084394A (en) * | 1984-12-24 | 1992-01-28 | Vogt Robert F | Method for corrective calibration of a flow cytometry using a mixture of fluorescent microbeads and cells |
US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
US4868126A (en) * | 1985-12-11 | 1989-09-19 | Flow Cytometry Standards Corporation | Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells |
US4714682A (en) * | 1985-12-11 | 1987-12-22 | Flow Cytometry Standards Corporation | Fluorescent calibration microbeads simulating stained cells |
US4867908A (en) * | 1986-08-29 | 1989-09-19 | Becton, Dickinson And Company | Method and materials for calibrating flow cytometers and other analysis instruments |
US4987086A (en) * | 1987-11-30 | 1991-01-22 | Becton, Dickinson And Company | Method for analysis of subpopulations of cells |
US5204884A (en) * | 1991-03-18 | 1993-04-20 | University Of Rochester | System for high-speed measurement and sorting of particles |
US5199576A (en) * | 1991-04-05 | 1993-04-06 | University Of Rochester | System for flexibly sorting particles |
-
1995
- 1995-12-27 US US08/579,186 patent/US5837547A/en not_active Expired - Lifetime
-
1996
- 1996-12-24 EP EP96945415A patent/EP0870195B1/de not_active Expired - Lifetime
- 1996-12-24 AU AU15671/97A patent/AU1567197A/en not_active Abandoned
- 1996-12-24 WO PCT/US1996/020608 patent/WO1997024613A1/en active IP Right Grant
- 1996-12-24 DE DE69633344T patent/DE69633344T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5837547A (en) | 1998-11-17 |
EP0870195A4 (de) | 2000-09-27 |
DE69633344T2 (de) | 2005-02-17 |
AU1567197A (en) | 1997-07-28 |
WO1997024613A1 (en) | 1997-07-10 |
EP0870195A1 (de) | 1998-10-14 |
EP0870195B1 (de) | 2004-09-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69633344D1 (de) | Kalibrierverfahren und vorrichtung fur durchflusscytometer | |
DE69628542D1 (de) | Verfahren und vorrichtung zur durchflusscytometrie | |
DE69623295D1 (de) | Saat-messmethode und vorrichtung | |
DE69631782D1 (de) | Vorrichtung und druckverfahren | |
DE69627668D1 (de) | Verfahren und vorrichtung für den chlamydiennachweis | |
DE69629144D1 (de) | Verfahren und Vorrichtung zur Kamerakontrolle | |
ATE304729T1 (de) | Verfahren und vorrichtung zur spielbetriebssteuerung | |
DE69816221D1 (de) | Sprachschnellheitsveränderungsverfahren und vorrichtung | |
DE59611451D1 (de) | Verfahren und Vorrichtung zur Einsatzoptimierung von Landmaschinen | |
DE69625224T2 (de) | Audiometrische vorrichtung und damit verbundenes aufspürungsverfahren | |
DE69611817T2 (de) | Vorrichtung zum implantieren und methode zum kollabieren derselben | |
DE69620224T2 (de) | Verfahren und vorrichtung zur aufzugsgruppensteuerung | |
DE69609608T2 (de) | Vorrichtung und verfahren zur unterbrechungszuweisung | |
DE69616142T2 (de) | Verfahren und Vorrichtung zur Flüssigentwicklung und Übertragung | |
DE69629612D1 (de) | Mengenmesser und damit ausgerüstete Vorrichtung zum Melken von Tieren | |
DE69604001D1 (de) | Verfahren und Vorrichtung zur optischen Verstärkung | |
DE69636138D1 (de) | Verfahren und Vorrichtung zur Kommunikationssteuerung | |
DE69628494D1 (de) | Vorrichtung und Verfahren zur Koordinateneingabe | |
DE59504023D1 (de) | Vorrichtung und ihre verwendung zur oxichlorierung | |
DE69516020D1 (de) | Schlitzauftragsverfahren und vorrichtung | |
DE69622420T2 (de) | Verfahren und vorrichtung zur reduzierung unerwünschter rückkopplung | |
DE69622467T2 (de) | Vorrichtung und Verfahren zum Mischen | |
DE59609675D1 (de) | Verfahren und Vorrichtung zur Abstandsmessung | |
DE69430119D1 (de) | Vorrichtung und verfahren zur motorregelung | |
DE59609753D1 (de) | Vorrichtung zum zumessen und zerstäuben von fluid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee | ||
8370 | Indication related to discontinuation of the patent is to be deleted |