DE69631656D1 - Debromhymenialdisin und verwandte verbindungen zur behandlung von osteoarthritis - Google Patents

Debromhymenialdisin und verwandte verbindungen zur behandlung von osteoarthritis

Info

Publication number
DE69631656D1
DE69631656D1 DE69631656T DE69631656T DE69631656D1 DE 69631656 D1 DE69631656 D1 DE 69631656D1 DE 69631656 T DE69631656 T DE 69631656T DE 69631656 T DE69631656 T DE 69631656T DE 69631656 D1 DE69631656 D1 DE 69631656D1
Authority
DE
Germany
Prior art keywords
debromhymenialdisin
treating osteoarthritis
related compounds
osteoarthritis
debromohymenialdisine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69631656T
Other languages
English (en)
Other versions
DE69631656T2 (de
Inventor
Stewart Chipman
John Faulkner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSTEOARTHRITIS SCIENCES Inc LI
University of California
Original Assignee
OSTEOARTHRITIS SCIENCES Inc LI
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OSTEOARTHRITIS SCIENCES Inc LI, University of California filed Critical OSTEOARTHRITIS SCIENCES Inc LI
Application granted granted Critical
Publication of DE69631656D1 publication Critical patent/DE69631656D1/de
Publication of DE69631656T2 publication Critical patent/DE69631656T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE69631656T 1995-06-07 1996-06-05 Debromhymenialdisin und verwandte verbindungen zur behandlung von osteoarthritis Expired - Fee Related DE69631656T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/472,902 US5591740A (en) 1995-06-07 1995-06-07 Use of debromohymenialdisine for treating osteoarthritis
US472902 1995-06-07
PCT/US1996/008822 WO1996040147A1 (en) 1995-06-07 1996-06-05 Use of debromohymenialdisine and related compounds for treating osteoarthritis

Publications (2)

Publication Number Publication Date
DE69631656D1 true DE69631656D1 (de) 2004-04-01
DE69631656T2 DE69631656T2 (de) 2004-12-16

Family

ID=23877364

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69631656T Expired - Fee Related DE69631656T2 (de) 1995-06-07 1996-06-05 Debromhymenialdisin und verwandte verbindungen zur behandlung von osteoarthritis

Country Status (8)

Country Link
US (1) US5591740A (de)
EP (1) EP0831834B1 (de)
JP (1) JPH11507048A (de)
AT (1) ATE260107T1 (de)
AU (1) AU699872B2 (de)
CA (1) CA2223581A1 (de)
DE (1) DE69631656T2 (de)
WO (1) WO1996040147A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU709191B2 (en) * 1995-09-11 1999-08-26 Osteoarthritis Sciences, Inc. Protein tyrosine kinase inhibitors for treating osteoarthritis
GB9608133D0 (en) * 1996-04-19 1996-06-26 Gemini International Holdings Diagnostic method and apparatus
US7067144B2 (en) * 1998-10-20 2006-06-27 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation
US6211361B1 (en) * 1999-07-20 2001-04-03 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon, State Univeristy Method for making debromohymenialdisine and analogs thereof
CA2378880C (en) * 1999-07-21 2010-02-23 Omeros Medical Systems, Inc. Solutions and methods for inhibition of pain, inflammation and cartilage degradation
DE69912808T2 (de) * 1999-12-08 2004-09-30 Centre National De La Recherche Scientifique (C.N.R.S.) Verwendung von Hymenialdisin und dessen Derivaten zur Herstellung therapeutischer Mittel
CA2397774A1 (en) * 2000-01-24 2001-07-26 Genzyme Corporation Jak/stat pathway inhibitors and the uses thereof
KR100404580B1 (ko) * 2000-04-20 2003-11-05 한국해양연구원 원도닌 ａ 및 그의 제조방법
CA2460539C (en) * 2001-09-15 2013-10-29 Rush-Presbyterian-St. Luke's Medical Center Stratified cartilage tissue and methods to engineer same
US20030165473A1 (en) * 2001-11-09 2003-09-04 Rush-Presbyterian-St. Luke's Medical Center Engineered intervertebral disc tissue
RU2005119173A (ru) * 2002-12-20 2006-02-27 Фармация Корпорейшн (Us) Ациклические пиразольные соединения
WO2004103958A2 (en) * 2003-05-19 2004-12-02 Michigan State University Preparation of hymenialdisine derivatives and use thereof
US20050074744A1 (en) * 2003-10-02 2005-04-07 Dibenedetto Peter Assays for evaluating anti-osteoarthritic activity
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US20070259030A1 (en) * 2006-05-05 2007-11-08 Drapeau Susan J Methods, systems and reagents for tendon and ligament therapy
WO2008147713A1 (en) * 2007-05-24 2008-12-04 The Regents Of The University Of California Wnt signaling inhibitors, and methods for making and using them
US20090281150A1 (en) * 2008-04-09 2009-11-12 Nicola Frances Bateman Compound 249

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3731293A (en) * 1992-02-24 1993-09-13 Smithkline Beecham Corporation Protein kinase c inhibitor

Also Published As

Publication number Publication date
EP0831834A1 (de) 1998-04-01
DE69631656T2 (de) 2004-12-16
JPH11507048A (ja) 1999-06-22
ATE260107T1 (de) 2004-03-15
AU6151696A (en) 1996-12-30
AU699872B2 (en) 1998-12-17
EP0831834B1 (de) 2004-02-25
CA2223581A1 (en) 1996-12-19
WO1996040147A1 (en) 1996-12-19
US5591740A (en) 1997-01-07

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee