DE69631044D1 - N,o-carboxymethylchitosan zur verhinderung operativ bedingter adhäsionen - Google Patents
N,o-carboxymethylchitosan zur verhinderung operativ bedingter adhäsionenInfo
- Publication number
- DE69631044D1 DE69631044D1 DE69631044T DE69631044T DE69631044D1 DE 69631044 D1 DE69631044 D1 DE 69631044D1 DE 69631044 T DE69631044 T DE 69631044T DE 69631044 T DE69631044 T DE 69631044T DE 69631044 D1 DE69631044 D1 DE 69631044D1
- Authority
- DE
- Germany
- Prior art keywords
- carboxymethylchitosan
- adhesions
- preventing
- operatively conditioned
- conditioned
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US436770 | 1995-05-08 | ||
US08/436,770 US5679658A (en) | 1995-05-08 | 1995-05-08 | N,O-carbonxymethylchitosan for prevention of surgical adhesions |
PCT/US1996/006339 WO1996035433A1 (en) | 1995-05-08 | 1996-05-06 | N,o-carboxymethylchitosan for prevention of surgical adhesions |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69631044D1 true DE69631044D1 (de) | 2004-01-22 |
DE69631044T2 DE69631044T2 (de) | 2004-07-22 |
Family
ID=23733768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69631044T Expired - Fee Related DE69631044T2 (de) | 1995-05-08 | 1996-05-06 | N,o-carboxymethylchitosan zur verhinderung operativ bedingter adhäsionen |
Country Status (8)
Country | Link |
---|---|
US (1) | US5679658A (de) |
EP (1) | EP0825867B1 (de) |
JP (1) | JPH11507018A (de) |
CA (1) | CA2220505C (de) |
DE (1) | DE69631044T2 (de) |
DK (1) | DK0825867T3 (de) |
ES (1) | ES2213175T3 (de) |
WO (1) | WO1996035433A1 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888988A (en) * | 1995-05-08 | 1999-03-30 | Chitogenics, Inc. | Covalently linked N,O-carboxymethylchitosan and uses thereof |
EP0830381A4 (de) * | 1995-06-09 | 2000-11-22 | William N Drohan | Chitinhydrogele, herstellungsverfahren und anwendung |
US7083777B1 (en) * | 1999-04-02 | 2006-08-01 | The Brigham And Women's Hospital, Inc. | Immunomodulating polymers |
EP1459757A1 (de) | 1999-04-02 | 2004-09-22 | The Brigham And Women's Hospital, Inc. | Immunomodulierende Polymere |
US6645947B1 (en) | 1999-05-20 | 2003-11-11 | Chitogenics, Inc. | Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins |
SV2003000753A (es) | 2000-12-05 | 2003-06-16 | Brigham & Womens Hospital | Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico |
US20040033265A1 (en) * | 2001-12-31 | 2004-02-19 | Industrial Technology Research Institute | Composite matrix containing chitosan derivatives and a process for making the same |
US7265097B2 (en) * | 2002-08-20 | 2007-09-04 | Chitogenics, Inc. | Methods of drug delivery using sulphated chitinous polymers |
JP2006522135A (ja) * | 2003-03-31 | 2006-09-28 | ザ ブライアム アンド ウィミンズ ホスピタル インコーポレーテッド | 喘息およびアレルギーの処置のための両性イオン免疫調節剤 |
US7332179B2 (en) * | 2003-12-12 | 2008-02-19 | Kimberly-Clark Worldwide, Inc. | Tissue products comprising a cleansing composition |
US20050244480A1 (en) * | 2004-04-30 | 2005-11-03 | Kimberly-Clark Worldwide, Inc. | Pre-wipes for improving anal cleansing |
US20060140899A1 (en) * | 2004-12-28 | 2006-06-29 | Kimberly-Clark Worldwide, Inc. | Skin cleansing system comprising an anti-adherent formulation and a cationic compound |
US7642395B2 (en) * | 2004-12-28 | 2010-01-05 | Kimberly-Clark Worldwide, Inc. | Composition and wipe for reducing viscosity of viscoelastic bodily fluids |
US8414907B2 (en) | 2005-04-28 | 2013-04-09 | Warsaw Orthopedic, Inc. | Coatings on medical implants to guide soft tissue healing |
WO2007092451A2 (en) | 2006-02-06 | 2007-08-16 | The Brigham And Women's Hospital, Inc. | Zwitterionic polysaccharides for promotion of immune system maturation and health |
US20070181631A1 (en) * | 2006-02-07 | 2007-08-09 | Ethicon Endo-Surgery, Inc. | Apparatus for performing trans-anal resection |
JP5489999B2 (ja) | 2007-08-28 | 2014-05-14 | アデレード リサーチ アンド イノベーション ピーティーワイ リミテッド | 外科用ハイドロゲル |
EP2217250A4 (de) | 2007-11-09 | 2011-01-05 | California Inst Of Techn | Immunmodulierende verbindungen und relevante zusammensetzungen und verfahren |
EP2095832A1 (de) | 2008-02-28 | 2009-09-02 | Bayer MaterialScience AG | Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile. |
BRPI0801422B8 (pt) | 2008-03-26 | 2021-05-25 | Fund Sao Francisco Xavier | composição e método para inibição da severidade das aderências pós-cirúrgicas |
US9198997B2 (en) | 2008-04-24 | 2015-12-01 | Medtronic, Inc. | Rehydratable thiolated polysaccharide particles and sponge |
WO2009132227A1 (en) * | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Protective gel based on chitosan and oxidized polysaccharide |
CA2721986C (en) | 2008-04-24 | 2017-03-14 | Medtronic, Inc. | Rehydratable polysaccharide particles and sponge |
WO2009132228A1 (en) | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Chitosan-containing protective composition |
US8556139B2 (en) * | 2008-12-04 | 2013-10-15 | Abdulmohsen A Almoumen | Multi-functional bag with cushion |
JP6027961B2 (ja) | 2010-04-07 | 2016-11-16 | シェン, ユエSHEN, Yue | 粘膜へ化合物を送るための媒体、それに関連する組成物、方法、及びシステム |
WO2011146910A1 (en) | 2010-05-20 | 2011-11-24 | Round June L | Antigen specific tregs and related compositions, methods and systems |
WO2013009945A1 (en) | 2011-07-12 | 2013-01-17 | The Brigham And Women's Hospital, Inc. | Lipid-containing psa compositions, methods of isolation and methods of use thereof |
EP2612846A1 (de) | 2012-01-09 | 2013-07-10 | Bayer MaterialScience AG | Beta-Aminosäureester und deren Verwendung |
EP2994161B1 (de) | 2013-05-10 | 2020-10-28 | California Institute of Technology | Probiotische prävention und behandlung von dickdarmkrebs |
CN104337834B (zh) * | 2014-11-10 | 2017-06-30 | 河北爱能生物科技股份有限公司 | 一种羧甲基壳聚糖灌肠液 |
WO2016201342A1 (en) | 2015-06-10 | 2016-12-15 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
EP3337321A4 (de) | 2015-08-19 | 2019-07-17 | President and Fellows of Harvard College | Lipidierte psa-zusammensetzungen und verfahren |
US11491181B2 (en) | 2016-07-15 | 2022-11-08 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
FR3074043B1 (fr) * | 2017-11-28 | 2020-11-13 | Kiomed Pharma | Chitosane a charge anionique |
FR3074044B1 (fr) * | 2017-11-28 | 2019-11-01 | Kiomed Pharma | Carboxyalkyl chitosane |
CN108744026A (zh) * | 2018-06-09 | 2018-11-06 | 江苏海尔滋生物科技有限公司 | 即配型几丁多糖冻干粉 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4141973A (en) * | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
SE456346B (sv) * | 1984-07-23 | 1988-09-26 | Pharmacia Ab | Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning |
US4619995A (en) * | 1984-12-24 | 1986-10-28 | Nova Chem Limited | N,O-carboxymethyl chitosan and preparative method therefor |
US4819617A (en) * | 1986-09-04 | 1989-04-11 | University Of Florida | Viscoelastic material for ophthalmic surgery |
US5080893A (en) * | 1988-05-31 | 1992-01-14 | University Of Florida | Method for preventing surgical adhesions using a dilute solution of polymer |
US5023090A (en) * | 1989-08-16 | 1991-06-11 | Levin Robert H | Topical compositions containing LYCD and other topically active medicinal ingredients for the treatment of ACNE |
US5140016A (en) * | 1988-05-31 | 1992-08-18 | University Of Florida | Method and composition for preventing surgical adhesions using a dilute solution of polymer |
US5093319A (en) * | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
US5462990A (en) * | 1990-10-15 | 1995-10-31 | Board Of Regents, The University Of Texas System | Multifunctional organic polymers |
WO1993013137A1 (en) * | 1991-12-20 | 1993-07-08 | Howmedica Inc. | Process for insolubilizing n-carboxyalkyl derivatives of chitosan |
US5411988A (en) * | 1993-10-27 | 1995-05-02 | Bockow; Barry I. | Compositions and methods for inhibiting inflammation and adhesion formation |
EP0665022A1 (de) * | 1994-01-28 | 1995-08-02 | Prodex, Inc. | Viskoelastische Lösung aus N,O-Carboxymethylchitosan zur opthalmischen Verwendung |
-
1995
- 1995-05-08 US US08/436,770 patent/US5679658A/en not_active Expired - Lifetime
-
1996
- 1996-05-06 ES ES96915517T patent/ES2213175T3/es not_active Expired - Lifetime
- 1996-05-06 DE DE69631044T patent/DE69631044T2/de not_active Expired - Fee Related
- 1996-05-06 WO PCT/US1996/006339 patent/WO1996035433A1/en active IP Right Grant
- 1996-05-06 CA CA002220505A patent/CA2220505C/en not_active Expired - Fee Related
- 1996-05-06 EP EP96915517A patent/EP0825867B1/de not_active Expired - Lifetime
- 1996-05-06 JP JP8534154A patent/JPH11507018A/ja active Pending
- 1996-05-06 DK DK96915517T patent/DK0825867T3/da active
Also Published As
Publication number | Publication date |
---|---|
DE69631044T2 (de) | 2004-07-22 |
DK0825867T3 (da) | 2004-04-13 |
EP0825867A1 (de) | 1998-03-04 |
ES2213175T3 (es) | 2004-08-16 |
EP0825867B1 (de) | 2003-12-10 |
EP0825867A4 (de) | 2000-05-31 |
WO1996035433A1 (en) | 1996-11-14 |
CA2220505A1 (en) | 1996-11-14 |
CA2220505C (en) | 2008-02-19 |
JPH11507018A (ja) | 1999-06-22 |
US5679658A (en) | 1997-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |