DE69628936D1 - Test zur identifikation von inhibitoren der interaktion zwischen p53 und dm2 proteinen - Google Patents
Test zur identifikation von inhibitoren der interaktion zwischen p53 und dm2 proteinenInfo
- Publication number
- DE69628936D1 DE69628936D1 DE69628936T DE69628936T DE69628936D1 DE 69628936 D1 DE69628936 D1 DE 69628936D1 DE 69628936 T DE69628936 T DE 69628936T DE 69628936 T DE69628936 T DE 69628936T DE 69628936 D1 DE69628936 D1 DE 69628936D1
- Authority
- DE
- Germany
- Prior art keywords
- formation
- dna
- interaction
- identification
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95810576 | 1995-09-18 | ||
EP95810576 | 1995-09-18 | ||
PCT/EP1996/003957 WO1997011367A1 (en) | 1995-09-18 | 1996-09-10 | ASSAY FOR IDENTIFYING INHIBITORS OF THE INTERACTION BETWEEN PROTEINS p53 AND dm2 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69628936D1 true DE69628936D1 (de) | 2003-08-07 |
DE69628936T2 DE69628936T2 (de) | 2004-05-27 |
Family
ID=8221793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69628936T Expired - Fee Related DE69628936T2 (de) | 1995-09-18 | 1996-09-10 | Test zur identifikation von inhibitoren der interaktion zwischen p53 und dm2 proteinen |
Country Status (7)
Country | Link |
---|---|
US (1) | US6492116B1 (de) |
EP (1) | EP0859956B1 (de) |
AT (1) | ATE244403T1 (de) |
AU (1) | AU7127296A (de) |
DE (1) | DE69628936T2 (de) |
WO (1) | WO1997011367A1 (de) |
ZA (1) | ZA967826B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9608937D0 (en) * | 1996-04-29 | 1996-07-03 | Cancer Res Campaign Tech | Screening methods for therapeutics and peptides used in the screen |
AU8284198A (en) * | 1997-07-02 | 1999-01-25 | Board Of Regents, The University Of Texas System | P53 as a regulator of cell differentiation |
DE19735221C1 (de) | 1997-08-14 | 1999-05-06 | Wolfgang Willi Prof Dr Deppert | Beeinflussung der Bindung von p53 an Zielgene |
US6020135A (en) * | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
DE69922372T2 (de) * | 1998-05-26 | 2005-12-15 | Agency For Science, Technology And Research | Polypeptide aus creb-binding-protein und verwandtem protein p300 für die verwendung bei der transkriptionsregulation |
MXPA06012294A (es) * | 2004-04-22 | 2007-03-15 | Johnson & Johnson | Complejos de proteina diminuta doble 2 humana-inhibidor y usos de los mismos. |
US20100129933A1 (en) * | 2007-04-26 | 2010-05-27 | Forschungszentrum Karlsruhe Gmbh | Method for detecting the binding between mdm2 and the proteasome |
WO2009070650A1 (en) * | 2007-11-26 | 2009-06-04 | The Research Foundation Of State University Of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5362623A (en) * | 1991-06-14 | 1994-11-08 | The John Hopkins University | Sequence specific DNA binding by p53 |
US5411860A (en) * | 1992-04-07 | 1995-05-02 | The Johns Hopkins University | Amplification of human MDM2 gene in human tumors |
US5770377A (en) * | 1994-07-20 | 1998-06-23 | University Of Dundee | Interruption of binding of MDM2 and P53 protein and therapeutic application thereof |
-
1996
- 1996-09-10 AU AU71272/96A patent/AU7127296A/en not_active Abandoned
- 1996-09-10 AT AT96932488T patent/ATE244403T1/de not_active IP Right Cessation
- 1996-09-10 EP EP96932488A patent/EP0859956B1/de not_active Expired - Lifetime
- 1996-09-10 DE DE69628936T patent/DE69628936T2/de not_active Expired - Fee Related
- 1996-09-10 WO PCT/EP1996/003957 patent/WO1997011367A1/en active IP Right Grant
- 1996-09-17 ZA ZA967826A patent/ZA967826B/xx unknown
-
2000
- 2000-06-26 US US09/603,052 patent/US6492116B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7127296A (en) | 1997-04-09 |
WO1997011367A1 (en) | 1997-03-27 |
EP0859956A1 (de) | 1998-08-26 |
EP0859956B1 (de) | 2003-07-02 |
ATE244403T1 (de) | 2003-07-15 |
DE69628936T2 (de) | 2004-05-27 |
US6492116B1 (en) | 2002-12-10 |
ZA967826B (en) | 1997-03-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |