DE69532062D1 - Immuntests von nicht-A, nicht-B Hepatitisvirus-verwandten Antigenen, monoklonale Antikörper und diese synthetisierende Hybridome - Google Patents

Immuntests von nicht-A, nicht-B Hepatitisvirus-verwandten Antigenen, monoklonale Antikörper und diese synthetisierende Hybridome

Info

Publication number
DE69532062D1
DE69532062D1 DE69532062T DE69532062T DE69532062D1 DE 69532062 D1 DE69532062 D1 DE 69532062D1 DE 69532062 T DE69532062 T DE 69532062T DE 69532062 T DE69532062 T DE 69532062T DE 69532062 D1 DE69532062 D1 DE 69532062D1
Authority
DE
Germany
Prior art keywords
immunoassays
monoclonal antibodies
hepatitis virus
related antigens
hybridomas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69532062T
Other languages
English (en)
Other versions
DE69532062T2 (de
Inventor
Tomiko Kashiwaguma
Shintaro Yagi
Akira Hasegawa
Tadahiro Kajita
Yohsuke Ohta
Hiroyuki Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RE, JP
Sysmex Corp
Advanced Life Science Institute Inc
Original Assignee
TOKYO METROPOLITAN ORG
International Reagents Corp
Advanced Life Science Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TOKYO METROPOLITAN ORG, International Reagents Corp, Advanced Life Science Institute Inc filed Critical TOKYO METROPOLITAN ORG
Publication of DE69532062D1 publication Critical patent/DE69532062D1/de
Application granted granted Critical
Publication of DE69532062T2 publication Critical patent/DE69532062T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69532062T 1994-07-12 1995-07-12 Immuntests von nicht-A, nicht-B Hepatitisvirus-verwandten Antigenen, monoklonale Antikörper und diese synthetisierende Hybridome Expired - Lifetime DE69532062T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18390494A JP3217600B2 (ja) 1994-07-12 1994-07-12 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
JP18390494 1994-07-12

Publications (2)

Publication Number Publication Date
DE69532062D1 true DE69532062D1 (de) 2003-12-11
DE69532062T2 DE69532062T2 (de) 2004-07-22

Family

ID=16143855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532062T Expired - Lifetime DE69532062T2 (de) 1994-07-12 1995-07-12 Immuntests von nicht-A, nicht-B Hepatitisvirus-verwandten Antigenen, monoklonale Antikörper und diese synthetisierende Hybridome

Country Status (4)

Country Link
US (1) US5871904A (de)
EP (1) EP0717104B1 (de)
JP (1) JP3217600B2 (de)
DE (1) DE69532062T2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698390A (en) 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
EP0967484B1 (de) * 1997-08-04 2007-05-02 Advanced Life Science Institute, Inc. Methoden zum nachweis und zur analyse von virus
FR2775690B1 (fr) * 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
CA2316130A1 (en) * 1999-08-19 2001-02-19 Masanori Fukui Method for detection or determination of hcv core antigens and reagent for detection or determination for use therein
DE60129598T2 (de) 2000-06-15 2008-04-17 Novartis Vaccines and Diagnostics, Inc., Emeryville Immunoassays für anti-hcv-antikörper
EP1829891B1 (de) 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Immuntests für Anti-HCV-Antikörper
US7049060B2 (en) * 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
KR20030094547A (ko) * 2002-06-04 2003-12-18 주식회사 서린바이오사이언스 모노클로날 항체를 생산하는 하이브리도마 세포주의선별을 위한 모노클로날항체 스크리닝 방법 및하이브리도마 선별용 키트
NZ538711A (en) * 2002-09-09 2007-01-26 Chiron Corp Antigen/antibody/antigen sandwich assays for detecting hepatitis C virus infections
US7827284B2 (en) * 2002-12-20 2010-11-02 Netsocket, Inc. Method and arrangement in a communication system
US8546075B2 (en) * 2003-10-28 2013-10-01 Advanced Life Science Institute, Inc. Method of detecting hepatitis C virus
EP1802778B1 (de) 2004-08-27 2011-10-05 Novartis Vaccines and Diagnostics, Inc. Hcv-antigene zur mehrfachen epitopfusion mit modifizierten proteolytischen spaltungsorten und verwendungen davon
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
EP3274478B1 (de) 2015-03-27 2020-09-23 Ortho-Clinical Diagnostics, Inc. Hcv-ns4a/modifizierte ns3-polypeptide und verwendungen davon
ES2796479T3 (es) 2016-05-31 2020-11-27 Hoffmann La Roche Procedimiento de pretratamiento para la detección rápida del antígeno central del VHC
EP3465217A1 (de) * 2016-05-31 2019-04-10 Roche Diagnostics GmbH Verfahren zum serologischen nachweis von virusantigenen
WO2023282243A1 (ja) 2021-07-06 2023-01-12 株式会社先端生命科学研究所 Ｅ型肝炎ウイルス感染の検出方法、ｅ型肝炎ウイルス感染検出用抗原ポリペプチド及びキット

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) 1987-11-18 2000-02-23 希龙股份有限公司 非ａ和非ｂ肝炎病毒的诊断及疫苗
UA50829C2 (uk) 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
KR0181517B1 (ko) * 1990-07-09 1999-04-01 나까하라 노부유끼 비-에이 비-비형 간염-특이 항원 및 간염 진단에서 그의 용도
WO1992007001A1 (en) * 1990-10-12 1992-04-30 Abbott Laboratories Hepatitis c virus antibody
JP3242402B2 (ja) * 1990-11-07 2001-12-25 アボット・ラボラトリーズ Ｃ型肝炎ウイルスに対するモノクローナル抗体およびその使用法
ATE167522T1 (de) * 1991-01-31 1998-07-15 Abbott Lab Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen
WO1992022571A1 (en) * 1991-06-13 1992-12-23 Baxter Diagnostics Inc. Immunoassay for non-a non-b hepatitis
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
AU2501392A (en) * 1991-08-21 1993-03-16 Abbott Laboratories Monoclonal antibodies to putative hcv ns5 proteins and methos for using same
AU2683792A (en) * 1991-09-16 1993-04-27 Genelabs Technologies, Inc. Peptide based hepatitis c virus immunoassays
ZA927837B (en) 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
US5437974A (en) * 1992-02-04 1995-08-01 Dade International Inc DNA sequence and encoded polypeptide useful in the diagnosis of hepatitis disease
EP1878797B1 (de) * 1992-07-16 2010-04-28 Advanced Life Science Institute, Inc Antigene Peptide zur Gruppierung des Hepatitis-C-Virus, Kit damit und Verfahren zur Gruppierung unter Verwendung dieses Kits
AU682335B2 (en) * 1992-12-29 1997-10-02 Akzo Nobel N.V. Monoclonal antibodies and anti-idiotypic antibodies to hepatitis C virus

Also Published As

Publication number Publication date
EP0717104A3 (de) 1997-02-26
JP3217600B2 (ja) 2001-10-09
EP0717104B1 (de) 2003-11-05
DE69532062T2 (de) 2004-07-22
US5871904A (en) 1999-02-16
JPH0829427A (ja) 1996-02-02
EP0717104A2 (de) 1996-06-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RE, JP

Owner name: SYSMEX CORP., KOBE, HYOGO, JP

Owner name: ADVANCED LIFE SCIENCE INSTITUTE,INC., SAITAMA, JP