DE69530669T2 - Vermischen von Flüssigkeiten mittels Elektroosmose - Google Patents

Vermischen von Flüssigkeiten mittels Elektroosmose

Info

Publication number
DE69530669T2
DE69530669T2 DE69530669T DE69530669T DE69530669T2 DE 69530669 T2 DE69530669 T2 DE 69530669T2 DE 69530669 T DE69530669 T DE 69530669T DE 69530669 T DE69530669 T DE 69530669T DE 69530669 T2 DE69530669 T2 DE 69530669T2
Authority
DE
Germany
Prior art keywords
electroosmosis
mixing liquids
liquids
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69530669T
Other languages
English (en)
Other versions
DE69530669D1 (de
Inventor
Fritz Bek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Deutschland GmbH
Original Assignee
Agilent Technologies Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Deutschland GmbH filed Critical Agilent Technologies Deutschland GmbH
Publication of DE69530669D1 publication Critical patent/DE69530669D1/de
Application granted granted Critical
Publication of DE69530669T2 publication Critical patent/DE69530669T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/05—Mixers using radiation, e.g. magnetic fields or microwaves to mix the material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/83—Forming a predetermined ratio of the substances to be mixed by controlling the ratio of two or more flows, e.g. using flow sensing or flow controlling devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D11/00—Control of flow ratio
    • G05D11/02—Controlling ratio of two or more flows of fluid or fluent material
    • G05D11/03—Controlling ratio of two or more flows of fluid or fluent material without auxiliary power
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N2030/285—Control of physical parameters of the fluid carrier electrically driven carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G01N2030/347—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient mixers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Automation & Control Theory (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DE69530669T 1995-02-18 1995-02-18 Vermischen von Flüssigkeiten mittels Elektroosmose Expired - Fee Related DE69530669T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95102304A EP0727661B1 (de) 1995-02-18 1995-02-18 Vermischen von Flüssigkeiten mittels Elektroosmose

Publications (2)

Publication Number Publication Date
DE69530669D1 DE69530669D1 (de) 2003-06-12
DE69530669T2 true DE69530669T2 (de) 2003-11-27

Family

ID=8218999

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69530669T Expired - Fee Related DE69530669T2 (de) 1995-02-18 1995-02-18 Vermischen von Flüssigkeiten mittels Elektroosmose

Country Status (4)

Country Link
US (1) US5785831A (de)
EP (1) EP0727661B1 (de)
JP (1) JPH08261986A (de)
DE (1) DE69530669T2 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329729C (zh) * 1996-06-28 2007-08-01 卡钳生命科学股份有限公司 微流体系统
US6012902A (en) * 1997-09-25 2000-01-11 Caliper Technologies Corp. Micropump
US5842787A (en) * 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US5992820A (en) * 1997-11-19 1999-11-30 Sarnoff Corporation Flow control in microfluidics devices by controlled bubble formation
US7105354B1 (en) 1998-06-12 2006-09-12 Asahi Kasei Kabushiki Kaisha Analyzer
US6482306B1 (en) * 1998-09-22 2002-11-19 University Of Washington Meso- and microfluidic continuous flow and stopped flow electroösmotic mixer
US6086243A (en) * 1998-10-01 2000-07-11 Sandia Corporation Electrokinetic micro-fluid mixer
US6062261A (en) * 1998-12-16 2000-05-16 Lockheed Martin Energy Research Corporation MicrofluIdic circuit designs for performing electrokinetic manipulations that reduce the number of voltage sources and fluid reservoirs
US6349740B1 (en) * 1999-04-08 2002-02-26 Abbott Laboratories Monolithic high performance miniature flow control unit
US6270641B1 (en) 1999-04-26 2001-08-07 Sandia Corporation Method and apparatus for reducing sample dispersion in turns and junctions of microchannel systems
US6406605B1 (en) 1999-06-01 2002-06-18 Ysi Incorporated Electroosmotic flow controlled microfluidic devices
US6444106B1 (en) 1999-07-09 2002-09-03 Orchid Biosciences, Inc. Method of moving fluid in a microfluidic device
US6271038B1 (en) * 1999-12-15 2001-08-07 Glaxo Wellcome Inc. Methods for high throughout determination and ranking of formulations and solubility
AU2001232805A1 (en) * 2000-01-12 2001-07-24 Ut-Battelle, Llc A microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream
US20020023841A1 (en) * 2000-06-02 2002-02-28 Ahn Chong H. Electrohydrodynamic convection microfluidic mixer
US7070681B2 (en) * 2001-01-24 2006-07-04 The Board Of Trustees Of The Leland Stanford Junior University Electrokinetic instability micromixer
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
JP3627060B1 (ja) * 2003-09-17 2005-03-09 学校法人慶應義塾 粒子分離方法及び装置
WO2005043112A2 (en) * 2003-09-30 2005-05-12 West Virginia University Research Corporation Apparatus and method for edman degradation on a microfluidic device utilizing an electroosmotic flow pump
WO2005036182A1 (ja) 2003-10-15 2005-04-21 Matsushita Electric Industrial Co., Ltd. キャピラリチップにおける流体の流通方法
US7588671B2 (en) * 2003-11-21 2009-09-15 Ebara Corporation Microfluidic treatment method and device
CN1752753B (zh) * 2004-09-22 2010-04-28 杭州生源医疗保健技术开发有限公司 离子膜微流量电渗泵
US8462605B2 (en) * 2005-05-09 2013-06-11 The Invention Science Fund I, Llc Method of manufacturing a limited use data storing device
US8159925B2 (en) 2005-08-05 2012-04-17 The Invention Science Fund I, Llc Limited use memory device with associated information
US8099608B2 (en) 2005-05-09 2012-01-17 The Invention Science Fund I, Llc Limited use data storing device
US7565596B2 (en) * 2005-09-09 2009-07-21 Searete Llc Data recovery systems
US8140745B2 (en) 2005-09-09 2012-03-20 The Invention Science Fund I, Llc Data retrieval methods
US8121016B2 (en) * 2005-05-09 2012-02-21 The Invention Science Fund I, Llc Rotation responsive disk activation and deactivation mechanisms
US20110181981A1 (en) * 2005-05-09 2011-07-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method and system for rotational control of data storage devices
US7596073B2 (en) * 2005-05-09 2009-09-29 Searete Llc Method and system for fluid mediated disk activation and deactivation
US9396752B2 (en) 2005-08-05 2016-07-19 Searete Llc Memory device activation and deactivation
US8220014B2 (en) * 2005-05-09 2012-07-10 The Invention Science Fund I, Llc Modifiable memory devices having limited expected lifetime
US7916592B2 (en) * 2005-05-09 2011-03-29 The Invention Science Fund I, Llc Fluid mediated disk activation and deactivation mechanisms
US8218262B2 (en) * 2005-05-09 2012-07-10 The Invention Science Fund I, Llc Method of manufacturing a limited use data storing device including structured data and primary and secondary read-support information
DE102006004887B4 (de) 2006-02-03 2010-07-22 Karlsruher Institut für Technologie Vorrichtung zur Erzeugung von Flüssigkeitsströmungen, Verfahren zu ihrer Herstellung und zu ihrem Betrieb sowie ihre Verwendung
US8264928B2 (en) * 2006-06-19 2012-09-11 The Invention Science Fund I, Llc Method and system for fluid mediated disk activation and deactivation
JP4893195B2 (ja) * 2006-09-27 2012-03-07 カシオ計算機株式会社 送液装置の接続構造体、燃料電池型発電装置及び電子機器
US8262880B2 (en) * 2010-03-09 2012-09-11 Empire Technology Development Llc Electrokinetic pumping of nonpolar solvents using ionic fluid
US9632066B2 (en) * 2015-04-09 2017-04-25 Ut-Battelle, Llc Open port sampling interface
US10060838B2 (en) 2015-04-09 2018-08-28 Ut-Battelle, Llc Capture probe
WO2018009222A1 (en) * 2016-07-08 2018-01-11 Hewlett-Packard Development Company, L.P. Microfluidic device for fluid mixture

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH679952A5 (de) * 1990-03-20 1992-05-15 Ciba Geigy Ag

Also Published As

Publication number Publication date
JPH08261986A (ja) 1996-10-11
US5785831A (en) 1998-07-28
EP0727661B1 (de) 2003-05-07
DE69530669D1 (de) 2003-06-12
EP0727661A1 (de) 1996-08-21

Similar Documents

Publication Publication Date Title
DE69530669D1 (de) Vermischen von Flüssigkeiten mittels Elektroosmose
DK0674888T3 (da) Blandeindretning
DE59601510D1 (de) Dosierpumpe
DE69628755D1 (de) Flüssigkeitspumpe
NO20000857D0 (no) Mikseapparat
FI963830A (fi) Nesterengaspumppu
DE69512979T2 (de) Flüssigkeitspumpe
DE69608694T2 (de) Tauchbarer mischrührer
DE59600062D1 (de) Mischvorrichtung
DE69622553D1 (de) Flüssiges urethan enthaltendes addukt
DE59607626D1 (de) Mischvorrichtung
DE69820935D1 (de) Fluidmischsystem
DE69611316D1 (de) Flüssigkeitspumpe
DE69618708D1 (de) Mischgerät
DE69721924T2 (de) Flüssigkeitspumpe
DE69631685D1 (de) Flüssigkeitsapplikator
DE69625749T2 (de) Flüssigkeitspumpe
DE59604876D1 (de) Flüssigkeitspumpe
PT904806E (pt) Disposiyivo de mistura de fluidos
DE69821296D1 (de) Mischen von flüssigen Gasen
DE69612672D1 (de) Mischvorrichtung
DE69621795D1 (de) Mischen
DE69616806D1 (de) Flüssige mehrkomponentenmischungen von azodinitrilen
DK33096A (da) Ringtrug-tvangsblander
KR970004178U (ko) 믹서기

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee