DE69530512D1 - Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten - Google Patents
Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthaltenInfo
- Publication number
- DE69530512D1 DE69530512D1 DE69530512T DE69530512T DE69530512D1 DE 69530512 D1 DE69530512 D1 DE 69530512D1 DE 69530512 T DE69530512 T DE 69530512T DE 69530512 T DE69530512 T DE 69530512T DE 69530512 D1 DE69530512 D1 DE 69530512D1
- Authority
- DE
- Germany
- Prior art keywords
- agents
- conjugating
- networking
- activated
- phosphatase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000001268 conjugating effect Effects 0.000 title abstract 4
- 239000003638 chemical reducing agent Substances 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000004132 cross linking Methods 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 230000021615 conjugation Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1652—Polyol derivatives esterified at least twice by thiophosphoric acid groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/815—Carrier is a synthetic polymer
- Y10S530/816—Attached to the carrier via a bridging agent
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/349,167 US5736624A (en) | 1994-12-02 | 1994-12-02 | Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents |
US349167 | 1994-12-02 | ||
PCT/US1995/015586 WO1996017580A2 (en) | 1994-12-02 | 1995-11-30 | Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69530512D1 true DE69530512D1 (de) | 2003-05-28 |
DE69530512T2 DE69530512T2 (de) | 2004-03-25 |
Family
ID=23371180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530512T Expired - Fee Related DE69530512T2 (de) | 1994-12-02 | 1995-11-30 | Phosphatase-aktivierte quervernetzende konjugierende und reduzierende agenzien, verfahren unter verwendung solcher agenzien und reagenzien die phosphatase-aktivierte quervernetzende und konjugierende agenzien enthalten |
Country Status (7)
Country | Link |
---|---|
US (4) | US5736624A (de) |
EP (1) | EP0795128B1 (de) |
JP (1) | JPH10509731A (de) |
AT (1) | ATE238549T1 (de) |
DE (1) | DE69530512T2 (de) |
ES (1) | ES2197214T3 (de) |
WO (1) | WO1996017580A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6403359B1 (en) | 1998-09-25 | 2002-06-11 | V. I. TECHNOLOGIES, Inc. | Solid phase quenching systems |
US6617100B2 (en) | 1998-09-25 | 2003-09-09 | V.I. Technologies, Inc. | Solid phase quenching systems |
BR0007437A (pt) | 1999-01-08 | 2001-11-20 | Procter & Gamble | Composições tópicas que compreendem tióisfuncionais protegidos |
US6703007B2 (en) * | 1999-01-08 | 2004-03-09 | The Procter & Gamble Company | Topical compositions comprising functional nucleophiles protected by phosphorus-containing moieties |
GB0002626D0 (en) | 2000-02-05 | 2000-03-29 | Eastman Kodak Co | Nonionic oligomeric surfactants and their use as dispersants and stabilisers |
US6995248B2 (en) * | 2001-07-16 | 2006-02-07 | Dr. Chip Biotechnology, Inc. | Immobilization of nucleic acids |
US20030198966A1 (en) * | 2002-04-19 | 2003-10-23 | Stojanovic Milan N. | Displacement assay for detection of small molecules |
US7470516B2 (en) * | 2003-04-14 | 2008-12-30 | The Trustees Of Columbia University In The City Of New York | Cross reactive arrays of three-way junction sensors for steroid determination |
US20040203007A1 (en) * | 2003-04-14 | 2004-10-14 | Stojanovic Milan N. | Cross reactive arrays of three-way junction sensors for steroid determination |
US7351591B2 (en) * | 2004-03-30 | 2008-04-01 | Intel Corporation | Surface modification of metals for biomolecule detection using surface enhanced Raman scattering (SERS) |
CA2606018A1 (en) * | 2005-04-28 | 2006-11-02 | Ventana Medical Systems, Inc. | Nanoparticle conjugates |
EP1877101B1 (de) | 2005-04-28 | 2016-11-16 | Ventana Medical Systems, Inc. | Mit antikörpern über einen heterobifuntionellen peg-linker konjugierte enzyme |
EP1951316B1 (de) | 2005-11-23 | 2015-08-19 | Ventana Medical Systems, Inc. | Molekulares Konjugat |
US7749957B2 (en) * | 2006-04-06 | 2010-07-06 | E.I. Du Pont De Nemours And Company | Clay-binding peptides and methods of use |
US7754680B2 (en) * | 2007-07-26 | 2010-07-13 | E. I. Du Pont De Nemours And Company | Peptides for binding calcium carbonates and methods of use |
CN114100588B (zh) * | 2020-08-31 | 2024-03-22 | 泉州师范学院 | 一种含氮功能基团超高交联吸附剂及其制备方法和血液灌流器 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1023287A (en) * | 1972-12-08 | 1977-12-27 | Boehringer Mannheim G.M.B.H. | Process for the preparation of carrier-bound proteins |
US4166105A (en) * | 1973-07-30 | 1979-08-28 | Block Engineering, Inc. | Dye tagged reagent |
US4169137A (en) * | 1974-12-20 | 1979-09-25 | Block Engineering, Inc. | Antigen detecting reagents |
SE427505B (sv) * | 1977-03-04 | 1983-04-11 | Pharmacia Diagnostics Ab | Reagens till anvendning vid immunkemiska bestemningsmetoder |
US4652524A (en) * | 1980-10-02 | 1987-03-24 | Ivan E. Modrovich | Soluble stabilized enzymes |
US4520110A (en) * | 1981-10-06 | 1985-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor |
US4542104A (en) * | 1983-04-06 | 1985-09-17 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Phycobiliprotein fluorescent conjugates |
US4657853A (en) * | 1984-09-14 | 1987-04-14 | E. I. Du Pont De Nemours And Company | Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody |
US4970074A (en) * | 1987-06-29 | 1990-11-13 | Abbott Laboratories | Fluorophores for encapsulation into liposomes |
US4994385A (en) * | 1987-10-30 | 1991-02-19 | Abbott Laboratories | Heterobifunctional coupling agents |
US4843126A (en) * | 1987-12-30 | 1989-06-27 | The Lubrizol Corporation | Aminoplast catalyst and compositions |
US5053520A (en) * | 1988-09-22 | 1991-10-01 | Abbott Laboratories | Heterobifunctional maleimido containing coupling agents |
DK589389D0 (da) * | 1989-11-23 | 1989-11-23 | Novo Nordisk As | Immobiliseret enzympraeparat |
US5376403A (en) * | 1990-02-09 | 1994-12-27 | Capote; Miguel A. | Electrically conductive compositions and methods for the preparation and use thereof |
WO1992008790A1 (en) * | 1990-11-14 | 1992-05-29 | Cargill, Incorporated | Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins |
US5191066A (en) * | 1990-12-07 | 1993-03-02 | Abbott Laboratories | Site-specific conjugation of immunoglobulins and detectable labels |
JP3125428B2 (ja) * | 1991-03-28 | 2001-01-15 | 和光純薬工業株式会社 | 修飾酵素 |
US5232484A (en) * | 1991-08-13 | 1993-08-03 | The Connecticut Agricultural Experiment Station | Degradation of pesticides by ferric reagents and peroxide in the presence of light |
CA2091544A1 (en) * | 1992-03-26 | 1993-09-27 | Shing F. Kwan | Stabilization of functional proteins |
US5674514A (en) * | 1992-09-21 | 1997-10-07 | Ciba-Geigy Corporation | Storage stable pesticidal aqueous emulsions |
WO1995002422A1 (en) * | 1993-07-12 | 1995-01-26 | Weltman Joel K | Method for conjugating nucleotides and nucleosides to disulfide-, maleimide-, and thiol-containing compounds |
US5571937A (en) * | 1994-05-13 | 1996-11-05 | Sloan-Kettering Institute For Cancer Research | Complementary DNA and toxins |
-
1994
- 1994-12-02 US US08/349,167 patent/US5736624A/en not_active Expired - Fee Related
-
1995
- 1995-11-30 JP JP8517656A patent/JPH10509731A/ja active Pending
- 1995-11-30 AT AT95943631T patent/ATE238549T1/de not_active IP Right Cessation
- 1995-11-30 DE DE69530512T patent/DE69530512T2/de not_active Expired - Fee Related
- 1995-11-30 ES ES95943631T patent/ES2197214T3/es not_active Expired - Lifetime
- 1995-11-30 EP EP95943631A patent/EP0795128B1/de not_active Expired - Lifetime
- 1995-11-30 WO PCT/US1995/015586 patent/WO1996017580A2/en active IP Right Grant
-
1996
- 1996-05-29 US US08/657,695 patent/US6057429A/en not_active Expired - Fee Related
- 1996-05-29 US US08/655,067 patent/US5789219A/en not_active Expired - Fee Related
-
2000
- 2000-02-03 US US09/498,388 patent/US6160153A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1996017580A3 (en) | 1996-10-10 |
ATE238549T1 (de) | 2003-05-15 |
US6160153A (en) | 2000-12-12 |
WO1996017580A2 (en) | 1996-06-13 |
EP0795128A2 (de) | 1997-09-17 |
US5789219A (en) | 1998-08-04 |
US5736624A (en) | 1998-04-07 |
DE69530512T2 (de) | 2004-03-25 |
US6057429A (en) | 2000-05-02 |
ES2197214T3 (es) | 2004-01-01 |
EP0795128B1 (de) | 2003-04-23 |
JPH10509731A (ja) | 1998-09-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |