DE69513632D1 - MICROGRANULATES CONTAINING 5-NITROIMIDAZOLE DERIVATIVES - Google Patents

MICROGRANULATES CONTAINING 5-NITROIMIDAZOLE DERIVATIVES

Info

Publication number
DE69513632D1
DE69513632D1 DE69513632T DE69513632T DE69513632D1 DE 69513632 D1 DE69513632 D1 DE 69513632D1 DE 69513632 T DE69513632 T DE 69513632T DE 69513632 T DE69513632 T DE 69513632T DE 69513632 D1 DE69513632 D1 DE 69513632D1
Authority
DE
Germany
Prior art keywords
microgranules
microgranulates
medicinal
nitroimidazole derivatives
hand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69513632T
Other languages
German (de)
Other versions
DE69513632T2 (en
Inventor
Gerard Leduc
Patrice Debregeas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethypharm SAS
Original Assignee
Ethypharm SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9400394A external-priority patent/FR2715067B1/en
Application filed by Ethypharm SAS filed Critical Ethypharm SAS
Publication of DE69513632D1 publication Critical patent/DE69513632D1/en
Application granted granted Critical
Publication of DE69513632T2 publication Critical patent/DE69513632T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Medicinal form contains a combination of microgranules of derivatives 5-nitroimidasole, consisting, on the one hand, of gastro-resistant microgranules and, on the other hand, of microgranules with a prolonged release of a medicinal agent. Gastroresistant microgranules are intended to guarantee the efficiency of the medicinal form of the present invention, primarily, in the upper part of gastrointestinal tract, while the microgranules with a prolonged medicinal agent release are operate mainly in the lower part of gastrointestinal tract.
DE69513632T 1994-01-14 1995-01-12 MICROGRANULATES CONTAINING 5-NITROIMIDAZOLE DERIVATIVES Expired - Fee Related DE69513632T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9400394A FR2715067B1 (en) 1994-01-14 1994-01-14 New dosage form of 5-nitro-imidazole derivatives effective for the treatment of parasitic infections and infections of the entire gastrointestinal tract.
PCT/FR1995/000039 WO1995019168A1 (en) 1994-01-14 1995-01-12 Microgranules of 5-nitro imidazole derivatives

Publications (2)

Publication Number Publication Date
DE69513632D1 true DE69513632D1 (en) 2000-01-05
DE69513632T2 DE69513632T2 (en) 2000-04-06

Family

ID=9459066

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69513632T Expired - Fee Related DE69513632T2 (en) 1994-01-14 1995-01-12 MICROGRANULATES CONTAINING 5-NITROIMIDAZOLE DERIVATIVES

Country Status (19)

Country Link
JP (1) JPH09507499A (en)
KR (1) KR100320140B1 (en)
CN (1) CN1088357C (en)
AT (1) ATE187068T1 (en)
AU (1) AU705570B2 (en)
BR (1) BR9506507A (en)
CZ (1) CZ286080B6 (en)
DE (1) DE69513632T2 (en)
DK (1) DK0739201T3 (en)
ES (1) ES2139883T3 (en)
MA (1) MA23429A1 (en)
MX (1) MX9602772A (en)
NZ (1) NZ279238A (en)
OA (1) OA10583A (en)
PL (1) PL178424B1 (en)
PT (1) PT739201E (en)
RU (1) RU2152212C1 (en)
SK (1) SK282066B6 (en)
UA (1) UA28031C2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4331930B2 (en) * 2001-10-17 2009-09-16 武田薬品工業株式会社 High content granules of acid labile drugs
JP6487534B2 (en) 2014-09-05 2019-03-20 シンビオミックス セラピューティクス、エルエルシー Sexidazole for use in the treatment of bacterial vaginitis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256684A (en) * 1985-06-13 1993-10-26 The Procter & Gamble Company Methods and compositions for the treatment of gastrointestinal disorders
DE3822095A1 (en) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab NEW MEDICAMENT FORMULATION AND METHOD FOR THE PRODUCTION THEREOF
EP0528971B1 (en) * 1990-05-14 1999-09-01 JERNBERG, Gary R. Surgical implant and method incorporating chemotherapeutic agents

Also Published As

Publication number Publication date
AU705570B2 (en) 1999-05-27
JPH09507499A (en) 1997-07-29
SK282066B6 (en) 2001-10-08
PL315530A1 (en) 1996-11-12
KR100320140B1 (en) 2002-07-02
ATE187068T1 (en) 1999-12-15
UA28031C2 (en) 2000-10-16
BR9506507A (en) 1997-09-09
CZ205596A3 (en) 1996-10-16
MA23429A1 (en) 1995-10-01
CN1138826A (en) 1996-12-25
CN1088357C (en) 2002-07-31
OA10583A (en) 2002-07-10
CZ286080B6 (en) 2000-01-12
ES2139883T3 (en) 2000-02-16
PL178424B1 (en) 2000-04-28
DK0739201T3 (en) 2000-05-01
MX9602772A (en) 1997-05-31
AU1580395A (en) 1995-08-01
DE69513632T2 (en) 2000-04-06
RU2152212C1 (en) 2000-07-10
PT739201E (en) 2000-05-31
NZ279238A (en) 1998-03-25
SK91496A3 (en) 1996-12-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee