DE69509510T2 - 2-(aminoalkoxy) phenylalkylamine mit entzündungskennenden eigenschaften - Google Patents
2-(aminoalkoxy) phenylalkylamine mit entzündungskennenden eigenschaftenInfo
- Publication number
- DE69509510T2 DE69509510T2 DE69509510T DE69509510T DE69509510T2 DE 69509510 T2 DE69509510 T2 DE 69509510T2 DE 69509510 T DE69509510 T DE 69509510T DE 69509510 T DE69509510 T DE 69509510T DE 69509510 T2 DE69509510 T2 DE 69509510T2
- Authority
- DE
- Germany
- Prior art keywords
- phenylalkylamine
- aminoalkoxy
- inflammatory properties
- inflammatory
- properties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000002757 inflammatory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9403639A GB9403639D0 (en) | 1994-02-25 | 1994-02-25 | Therapeutic agents |
PCT/EP1995/000626 WO1995023127A1 (en) | 1994-02-25 | 1995-02-20 | 2-(aminoalkoxy)phenylalkylamines with antiinflammatory activity |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69509510D1 DE69509510D1 (de) | 1999-06-10 |
DE69509510T2 true DE69509510T2 (de) | 1999-09-02 |
Family
ID=10750910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69509510T Expired - Fee Related DE69509510T2 (de) | 1994-02-25 | 1995-02-20 | 2-(aminoalkoxy) phenylalkylamine mit entzündungskennenden eigenschaften |
Country Status (9)
Country | Link |
---|---|
US (1) | US5736568A (de) |
EP (1) | EP0750607B1 (de) |
JP (1) | JPH09509422A (de) |
AU (1) | AU1758695A (de) |
DE (1) | DE69509510T2 (de) |
GB (1) | GB9403639D0 (de) |
IL (1) | IL112728A0 (de) |
WO (1) | WO1995023127A1 (de) |
ZA (1) | ZA951420B (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001286965A1 (en) * | 2000-08-31 | 2002-03-13 | Advanced Medicine, Inc. | Sodium channel modulators |
DE10257356A1 (de) * | 2002-12-09 | 2004-06-24 | Bayer Ag | Fluorhaltige Aromaten |
DK3319969T3 (da) * | 2015-07-06 | 2024-07-08 | Turning Point Therapeutics Inc | Diaryl-makrocyklus-polymorf |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3047628A (en) * | 1957-02-19 | 1962-07-31 | Hoffmann La Roche | Benzylamine derivatives |
BE792959A (fr) * | 1972-01-14 | 1973-04-16 | Bottu | Nouvelles benzylamines utiles comme anti-inflammatoires et analgesiqueset leur procede de preparation |
US4064125A (en) * | 1976-10-29 | 1977-12-20 | E. R. Squibb And Sons, Inc. | Substituted amides having antiinflammatory activity |
US4098789A (en) * | 1977-03-02 | 1978-07-04 | E. R. Squibb & Sons, Inc. | Omega-(n-aminoalkoxybenzyl-amino)-(n-hydrocarbonoyl-amino)-alkanoic acid esters |
GB1604675A (en) * | 1978-05-08 | 1981-12-16 | Allen & Hanburys Ltd | Aminoalkylbenzenes |
US4156079A (en) * | 1978-06-19 | 1979-05-22 | E. R. Squibb & Sons, Inc. | Substituted amides having antiinflammatory activity |
US4214081A (en) * | 1978-06-19 | 1980-07-22 | E. R. Squibb & Sons, Inc. | Imino containing morpholine compounds |
US4199528A (en) * | 1978-06-19 | 1980-04-22 | E. R. Squibb & Sons, Inc. | Substituted amides having antiinflammatory activity |
-
1994
- 1994-02-25 GB GB9403639A patent/GB9403639D0/en active Pending
-
1995
- 1995-02-20 AU AU17586/95A patent/AU1758695A/en not_active Abandoned
- 1995-02-20 EP EP95910506A patent/EP0750607B1/de not_active Expired - Lifetime
- 1995-02-20 US US08/687,584 patent/US5736568A/en not_active Expired - Lifetime
- 1995-02-20 DE DE69509510T patent/DE69509510T2/de not_active Expired - Fee Related
- 1995-02-20 JP JP7522119A patent/JPH09509422A/ja not_active Ceased
- 1995-02-20 WO PCT/EP1995/000626 patent/WO1995023127A1/en active IP Right Grant
- 1995-02-21 IL IL11272895A patent/IL112728A0/xx unknown
- 1995-02-21 ZA ZA951420A patent/ZA951420B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US5736568A (en) | 1998-04-07 |
EP0750607B1 (de) | 1999-05-06 |
WO1995023127A1 (en) | 1995-08-31 |
DE69509510D1 (de) | 1999-06-10 |
JPH09509422A (ja) | 1997-09-22 |
AU1758695A (en) | 1995-09-11 |
IL112728A0 (en) | 1995-12-08 |
EP0750607A1 (de) | 1997-01-02 |
GB9403639D0 (en) | 1994-04-13 |
ZA951420B (en) | 1995-08-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |