DE69506387D1 - BINDING TEST USING AGENTS WITH TAIL GROUPS - Google Patents

BINDING TEST USING AGENTS WITH TAIL GROUPS

Info

Publication number
DE69506387D1
DE69506387D1 DE69506387T DE69506387T DE69506387D1 DE 69506387 D1 DE69506387 D1 DE 69506387D1 DE 69506387 T DE69506387 T DE 69506387T DE 69506387 T DE69506387 T DE 69506387T DE 69506387 D1 DE69506387 D1 DE 69506387D1
Authority
DE
Germany
Prior art keywords
agents
binding test
tail groups
tail
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69506387T
Other languages
German (de)
Other versions
DE69506387T2 (en
Inventor
Roger Ekins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Multilyte Ltd
Original Assignee
Multilyte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Multilyte Ltd filed Critical Multilyte Ltd
Application granted granted Critical
Publication of DE69506387D1 publication Critical patent/DE69506387D1/en
Publication of DE69506387T2 publication Critical patent/DE69506387T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies
DE69506387T 1994-03-11 1995-03-10 BINDING TEST USING AGENTS WITH TAIL GROUPS Expired - Lifetime DE69506387T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9404709A GB9404709D0 (en) 1994-03-11 1994-03-11 Binding assay
PCT/GB1995/000521 WO1995024649A1 (en) 1994-03-11 1995-03-10 Binding assay using binding agents with tail groups

Publications (2)

Publication Number Publication Date
DE69506387D1 true DE69506387D1 (en) 1999-01-14
DE69506387T2 DE69506387T2 (en) 1999-05-12

Family

ID=10751658

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69506387T Expired - Lifetime DE69506387T2 (en) 1994-03-11 1995-03-10 BINDING TEST USING AGENTS WITH TAIL GROUPS

Country Status (10)

Country Link
US (3) US6316186B1 (en)
EP (1) EP0749581B1 (en)
JP (2) JP3431160B2 (en)
AU (1) AU1857195A (en)
DE (1) DE69506387T2 (en)
ES (1) ES2127514T3 (en)
FI (1) FI114826B (en)
GB (1) GB9404709D0 (en)
HK (1) HK1014044A1 (en)
WO (1) WO1995024649A1 (en)

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GB9404709D0 (en) * 1994-03-11 1994-04-27 Multilyte Ltd Binding assay
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
SE9604575D0 (en) 1996-12-12 1996-12-12 Biacore Ab Method and system for analyte determination
WO1998045684A1 (en) * 1997-04-04 1998-10-15 Biosite Diagnostics, Inc. Methods for concentrating ligands using magnetic particles
DE19741716A1 (en) * 1997-09-22 1999-03-25 Hoechst Ag Recognition system
US7157234B2 (en) 1997-10-24 2007-01-02 Beckman Coulter, Inc. Detection of very low quantities of analyte bound to a solid phase
AUPP103497A0 (en) * 1997-12-19 1998-01-15 Panbio Pty Ltd Assay apparatus
JP2002502977A (en) 1998-02-04 2002-01-29 インビトロジェン コーポレイション Microarrays and their uses
US20010026919A1 (en) * 2000-02-08 2001-10-04 Alex Chenchik Nucleic acid assays employing universal arrays
AU5951201A (en) 2000-05-04 2001-11-12 Univ Yale High density protein arrays for screening of protein activity
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7892854B2 (en) 2000-06-21 2011-02-22 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
JP4115833B2 (en) 2000-10-12 2008-07-09 ユニバーシティー、オブ、メディシン、アンド、デンティストリー、オブ、ニュージャージー Oligonucleotide promoted coalescence
US20030082571A1 (en) * 2001-04-10 2003-05-01 Kachab Edward Hanna Linear nucleic acid and sequence therefor
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
US20040161741A1 (en) 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
US9777312B2 (en) 2001-06-30 2017-10-03 Enzo Life Sciences, Inc. Dual polarity analysis of nucleic acids
KR20040068122A (en) 2001-10-15 2004-07-30 바이오어레이 솔루션스 리미티드 Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
US7041453B2 (en) * 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
US7229763B2 (en) * 2003-04-07 2007-06-12 Beckman Coulter, Inc. Assay system using labeled oligonucleotides
US20040229226A1 (en) * 2003-05-16 2004-11-18 Reddy M. Parameswara Reducing microarray variation with internal reference spots
WO2005029705A2 (en) 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
AU2004286252A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
WO2005045060A2 (en) 2003-10-29 2005-05-19 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
CA2558271A1 (en) * 2004-03-05 2005-09-15 Nisshinbo Industries, Inc. Immobilized biomolecule and method of detecting substance capable of interacting with biomolecule
ATE527059T1 (en) * 2004-03-18 2011-10-15 Nissui Pharm Co Ltd METHOD OF MAKING AN ANALYTICAL APPARATUS AND KIT
US7364898B2 (en) * 2004-05-04 2008-04-29 Eppendorf Ag Customized micro-array construction and its use for target molecule detection
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
GB0421838D0 (en) 2004-09-30 2004-11-03 Congenia S R L Cancer markers
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
JP4243319B2 (en) * 2006-04-28 2009-03-25 凸版印刷株式会社 Protein chip
CA2659745A1 (en) * 2006-08-02 2008-02-07 California Institute Of Technology Methods and systems for detecting and/or sorting targets
US20090032446A1 (en) * 2007-08-01 2009-02-05 Triwatech, L.L.C. Mobile station and methods for diagnosing and modeling site specific effluent treatment facility requirements
SE533515C2 (en) 2008-04-16 2010-10-12 Aamic Ab Analysis procedure for simultaneous analysis of several analytes
US8309306B2 (en) * 2008-11-12 2012-11-13 Nodality, Inc. Detection composition
WO2010085548A2 (en) * 2009-01-22 2010-07-29 Li-Cor, Inc. Single molecule proteomics with dynamic probes
GB201016403D0 (en) 2010-09-29 2010-11-10 Bath Ventures Novel interaction between staphylococcus aureus Sbi and C3d protiens
GB201021909D0 (en) 2010-12-23 2011-02-02 Randox Lab Ltd Multi-analyte microarrays using tag-specific antibodies and tag-anchored antibodies
AU2018400335A1 (en) * 2018-01-05 2020-07-02 Quotient Suisse Sa Self-assembling diagnostic array platform
KR102627534B1 (en) 2018-06-21 2024-01-19 에프. 호프만-라 로슈 아게 All-LNA oligonucleotide hybridization
WO2020099533A1 (en) 2018-11-16 2020-05-22 F. Hoffmann-La Roche Ag Streptavidin-coated solid phases with a member of a binding pair
WO2020245377A1 (en) 2019-06-07 2020-12-10 F. Hoffmann-La Roche Ag Hybridizing all-lna oligonucleotides

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1944283A (en) 1982-08-27 1984-03-29 Ekins Roger Philip Measurement of analyte concentration
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
WO1990011372A1 (en) * 1989-03-21 1990-10-04 Collaborative Research, Inc. Multiplex dna diagnostic test
US5120662A (en) 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
EP0422861B1 (en) 1989-10-13 2000-05-17 Zeneca Limited Probes
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
JPH04273065A (en) 1991-02-28 1992-09-29 Hitachi Ltd Immunity analyzing method and device
US5646001A (en) * 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
JP3197277B2 (en) * 1993-05-10 2001-08-13 日水製薬株式会社 Method for analyzing one or more immunological ligands, analytical reagents and kits
GB9404709D0 (en) * 1994-03-11 1994-04-27 Multilyte Ltd Binding assay
US5648213A (en) * 1994-08-30 1997-07-15 Beckman Instruments, Inc. Compositions and methods for use in detection of analytes
US6287778B1 (en) * 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags

Also Published As

Publication number Publication date
AU1857195A (en) 1995-09-25
DE69506387T2 (en) 1999-05-12
FI963560A (en) 1996-09-10
JP3619222B2 (en) 2005-02-09
HK1014044A1 (en) 1999-09-17
WO1995024649A1 (en) 1995-09-14
US6316186B1 (en) 2001-11-13
JP2003156493A (en) 2003-05-30
US20020182617A1 (en) 2002-12-05
JP3431160B2 (en) 2003-07-28
EP0749581B1 (en) 1998-12-02
JPH10512664A (en) 1998-12-02
ES2127514T3 (en) 1999-04-16
GB9404709D0 (en) 1994-04-27
EP0749581A1 (en) 1996-12-27
FI114826B (en) 2004-12-31
US7588893B2 (en) 2009-09-15
US20060204983A1 (en) 2006-09-14
FI963560A0 (en) 1996-09-10

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Legal Events

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