DE69416835D1 - Kondensierte 4-aminopyridine mit antirheumatischer wirkung - Google Patents

Kondensierte 4-aminopyridine mit antirheumatischer wirkung

Info

Publication number
DE69416835D1
DE69416835D1 DE69416835T DE69416835T DE69416835D1 DE 69416835 D1 DE69416835 D1 DE 69416835D1 DE 69416835 T DE69416835 T DE 69416835T DE 69416835 T DE69416835 T DE 69416835T DE 69416835 D1 DE69416835 D1 DE 69416835D1
Authority
DE
Germany
Prior art keywords
aminopyridine
condensed
antirheumatic effect
antirheumatic
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69416835T
Other languages
English (en)
Other versions
DE69416835T2 (de
Inventor
Bernard Armitage
Bruce Leslie
Thomas Miller
Christopher Morley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Application granted granted Critical
Publication of DE69416835D1 publication Critical patent/DE69416835D1/de
Publication of DE69416835T2 publication Critical patent/DE69416835T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69416835T 1993-06-22 1994-06-10 Kondensierte 4-aminopyridine mit antirheumatischer wirkung Expired - Fee Related DE69416835T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939312891A GB9312891D0 (en) 1993-06-22 1993-06-22 Therapeutic agents
PCT/EP1994/001923 WO1995000511A1 (en) 1993-06-22 1994-06-10 Condensed 4-aminopyridines with antirheumatic activity

Publications (2)

Publication Number Publication Date
DE69416835D1 true DE69416835D1 (de) 1999-04-08
DE69416835T2 DE69416835T2 (de) 1999-07-01

Family

ID=10737603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69416835T Expired - Fee Related DE69416835T2 (de) 1993-06-22 1994-06-10 Kondensierte 4-aminopyridine mit antirheumatischer wirkung

Country Status (7)

Country Link
US (1) US5780482A (de)
EP (1) EP0705260B1 (de)
JP (1) JPH08511787A (de)
AU (1) AU7071794A (de)
DE (1) DE69416835T2 (de)
GB (1) GB9312891D0 (de)
WO (1) WO1995000511A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR004010A1 (es) 1995-10-11 1998-09-30 Glaxo Group Ltd Compuestos heterociclicos
RS49779B (sr) 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
DK1171440T3 (da) * 1999-04-21 2004-08-02 Wyeth Corp Substituerede 3-cyano-[1,7]-, [1,5]- og [1,8]-naphthyridininhibitorer af tyrosinkinaser
US6933299B1 (en) 1999-07-09 2005-08-23 Smithkline Beecham Corporation Anilinoquinazolines as protein tyrosine kinase inhibitors
AU5783300A (en) 1999-07-09 2001-01-30 Glaxo Group Limited Anilinoquinazolines as protein tyrosine kinase inhibitors
US6608048B2 (en) 2000-03-28 2003-08-19 Wyeth Holdings Tricyclic protein kinase inhibitors
EP1412367A4 (de) 2001-06-21 2006-05-03 Ariad Pharma Inc Neue chinoline und deren verwendung
AU2002365352A1 (en) * 2001-11-27 2003-06-10 Corporation For National Research Initiatives A miniature condenser microphone and fabrication method therefor
US7279487B2 (en) 2002-01-17 2007-10-09 Merck & Co., Inc. Hydroxynaphthyridinone carboxamides useful as HIV integrase inhibitors
EP1633718B1 (de) * 2003-06-17 2012-06-06 Millennium Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur inhibierung von tgf-s
US7547782B2 (en) * 2005-09-30 2009-06-16 Bristol-Myers Squibb Company Met kinase inhibitors
EP2345652A1 (de) 2005-12-21 2011-07-20 Abbott Laboratories Antivirale Verbindungen
EP1971611B1 (de) 2005-12-21 2012-10-10 Abbott Laboratories Antivirale verbindungen
AU2006330924B2 (en) 2005-12-21 2012-03-15 Abbvie Inc. Anti-viral compounds
TWI392677B (zh) * 2005-12-21 2013-04-11 Abbott Lab 抗病毒化合物、其製備方法及用途
RU2467007C2 (ru) * 2005-12-21 2012-11-20 Эбботт Лэборетриз Производные [1,8]нафтиридина, полезные в качестве ингибиторов репликации вируса hcv
TWI399380B (zh) 2006-12-20 2013-06-21 Abbott Lab 抗病毒化合物
CA2682504C (en) * 2007-04-05 2012-10-30 Amgen Inc. Aurora kinase modulators and method of use
JP5584215B2 (ja) * 2008-09-02 2014-09-03 ノバルティス アーゲー ヘテロ環ｐｉｍキナーゼ阻害剤
CA2750047A1 (en) 2009-01-21 2010-07-29 Basilea Pharmaceutica Ag Novel bicyclic antibiotics
ES2432070T3 (es) 2009-02-24 2013-11-29 Respiratorius Ab Diazaheteroarilos broncodilatadores novedosos
CA2765823A1 (en) * 2009-06-25 2010-12-29 Amgen Inc. Tricyclic heterocyclic compounds as mediators of p13k activity
US10239875B2 (en) 2017-06-16 2019-03-26 King Saud University Naphthyridinyl hydrazine derivatives as potent peripheral analgesic agents
EA202190024A1 (ru) * 2018-06-21 2021-05-19 Селлестия Биотек Аг Способ получения амино-диариловых эфиров и гидрохлоридных солей амино-диариловых эфиров

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466965A (en) * 1982-07-26 1984-08-21 American Hospital Supply Corporation Phthalazine compounds, compositions and use
NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
EP0222839A4 (de) * 1985-05-17 1988-11-09 Univ Australian Antimalariaverbindungen.
JPS6368568A (ja) * 1986-09-10 1988-03-28 Otsuka Pharmaceut Factory Inc ｐ−アミノフエノ−ル誘導体
EP0362299A1 (de) * 1987-07-22 1990-04-11 Schering Corporation Bizyklische verbindungen, deren verwendung als arzneimittel, deren herstellung und zwischenverbindungen bei ihrer herstellung
US4978661A (en) * 1988-09-29 1990-12-18 Innocenzo Caruso Use of 6-halo-4-quinolone compounds and pharmaceutical compositions thereof for the preparation of a medicament for the therapeutical application in rheumatoid arthritis
GR900100380A (el) * 1989-05-20 1991-10-10 Fisons Plc Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives
JP2988739B2 (ja) * 1990-04-16 1999-12-13 協和醗酵工業株式会社 １，８−ナフチリジン−２−オン誘導体
GB9127252D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
JPH08511787A (ja) 1996-12-10
DE69416835T2 (de) 1999-07-01
EP0705260A1 (de) 1996-04-10
AU7071794A (en) 1995-01-17
WO1995000511A1 (en) 1995-01-05
EP0705260B1 (de) 1999-03-03
US5780482A (en) 1998-07-14
GB9312891D0 (en) 1993-08-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ABBOTT GMBH & CO. KG, 65205 WIESBADEN, DE

8339 Ceased/non-payment of the annual fee