DE69406806D1 - Kombinatorische Bibliotheken und Verfahren zu ihrer Verwendung - Google Patents
Kombinatorische Bibliotheken und Verfahren zu ihrer VerwendungInfo
- Publication number
- DE69406806D1 DE69406806D1 DE69406806T DE69406806T DE69406806D1 DE 69406806 D1 DE69406806 D1 DE 69406806D1 DE 69406806 T DE69406806 T DE 69406806T DE 69406806 T DE69406806 T DE 69406806T DE 69406806 D1 DE69406806 D1 DE 69406806D1
- Authority
- DE
- Germany
- Prior art keywords
- different
- subunit
- polysubunits
- methods
- combinatorial libraries
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00592—Split-and-pool, mix-and-divide processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16896693A | 1993-12-15 | 1993-12-15 | |
PCT/US1994/008542 WO1995016918A1 (en) | 1993-12-15 | 1994-07-26 | Combinatorial libraries and methods for their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69406806D1 true DE69406806D1 (de) | 1997-12-18 |
Family
ID=22613731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69406806T Expired - Lifetime DE69406806D1 (de) | 1993-12-15 | 1994-07-26 | Kombinatorische Bibliotheken und Verfahren zu ihrer Verwendung |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0734530B1 (de) |
JP (1) | JPH09506611A (de) |
AT (1) | ATE160223T1 (de) |
AU (1) | AU7552394A (de) |
DE (1) | DE69406806D1 (de) |
SG (1) | SG48166A1 (de) |
WO (1) | WO1995016918A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69430727T2 (de) | 1993-07-26 | 2003-03-06 | Innovasive Devices, Inc. | Greifereinrichtung für nahtmaterial |
CA2252408A1 (en) | 1996-04-24 | 1997-11-13 | Peptide Therapeutics Limited | Auto-deconvoluting combinatorial libraries |
CA2335951C (en) | 1998-06-24 | 2013-07-30 | Mark S. Chee | Decoding of array sensors with microspheres |
CZ20004794A3 (cs) | 1998-06-24 | 2001-08-15 | Aventis Pharmaceuticals Products, Inc. | Fluorfenylové sloučeniny vázané k polymernímu nosiči |
IL143266A0 (en) | 1998-11-27 | 2002-04-21 | Darwin Discovery Ltd | Transforming growth factor-beta binding proteins and pharmaceutical compositions for increasing bone mineral content utilizing the same |
US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
US8481268B2 (en) | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
WO2001012862A2 (en) * | 1999-08-18 | 2001-02-22 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
DE60136166D1 (de) | 2000-02-07 | 2008-11-27 | Illumina Inc | Nukleinsäure-nachweisverfahren mit universellem priming |
US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
CA2401962A1 (en) | 2000-02-07 | 2001-08-09 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
US7361488B2 (en) | 2000-02-07 | 2008-04-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
AU3838901A (en) | 2000-02-16 | 2001-08-27 | Illumina Inc | Parallel genotyping of multiple patient samples |
DE60228477D1 (de) | 2001-05-08 | 2008-10-02 | Darwin Molecular Corp | Verfahren zur regulierung der immunfunktion in primaten unter verwendung des foxp3-proteins |
EP2258724A1 (de) | 2002-11-21 | 2010-12-08 | Celltech R & D, Inc. | Modulierung von Immunantworten mittels multimeriserter Anti-CD83 Antikörper |
WO2008067196A2 (en) | 2006-11-16 | 2008-06-05 | The Regents Of The University Of California | Methods for identifying inhibitors of solute transporters |
US20110015239A1 (en) | 2007-12-14 | 2011-01-20 | The Regents Of The University Of California | Inhibitors of calcium-activated chloride channels |
TWI492951B (zh) | 2007-12-31 | 2015-07-21 | Baxter Int | 表現人類凝血因子的基因轉殖非人類動物及其用途 |
AU2012328457A1 (en) | 2011-10-28 | 2014-04-24 | Presage Biosciences, Inc. | Methods for drug delivery |
CA3217862A1 (en) | 2021-05-05 | 2022-11-10 | Radius Pharmaceuticals, Inc. | Animal model having homologous recombination of mouse pth1 receptor |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650489A (en) * | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
AU668347B2 (en) * | 1990-11-21 | 1996-05-02 | Torrey Pines Institute For Molecular Studies | Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures |
US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
-
1994
- 1994-07-26 EP EP94925706A patent/EP0734530B1/de not_active Expired - Lifetime
- 1994-07-26 SG SG1996007530A patent/SG48166A1/en unknown
- 1994-07-26 JP JP7516736A patent/JPH09506611A/ja not_active Ceased
- 1994-07-26 AT AT94925706T patent/ATE160223T1/de not_active IP Right Cessation
- 1994-07-26 DE DE69406806T patent/DE69406806D1/de not_active Expired - Lifetime
- 1994-07-26 AU AU75523/94A patent/AU7552394A/en not_active Abandoned
- 1994-07-26 WO PCT/US1994/008542 patent/WO1995016918A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ATE160223T1 (de) | 1997-11-15 |
EP0734530B1 (de) | 1997-11-12 |
JPH09506611A (ja) | 1997-06-30 |
EP0734530A1 (de) | 1996-10-02 |
SG48166A1 (en) | 1998-04-17 |
WO1995016918A1 (en) | 1995-06-22 |
AU7552394A (en) | 1995-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |