DE69214383D1 - Reagenz für Bilderzeugung und Therapie von Tumoren - Google Patents
Reagenz für Bilderzeugung und Therapie von TumorenInfo
- Publication number
- DE69214383D1 DE69214383D1 DE69214383T DE69214383T DE69214383D1 DE 69214383 D1 DE69214383 D1 DE 69214383D1 DE 69214383 T DE69214383 T DE 69214383T DE 69214383 T DE69214383 T DE 69214383T DE 69214383 D1 DE69214383 D1 DE 69214383D1
- Authority
- DE
- Germany
- Prior art keywords
- oligopeptides
- therapy
- ldv
- imaging
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 238000003384 imaging method Methods 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 6
- 102000015636 Oligopeptides Human genes 0.000 abstract 6
- 238000001727 in vivo Methods 0.000 abstract 2
- 101710112752 Cytotoxin Proteins 0.000 abstract 1
- QCSFMCFHVGTLFF-NHCYSSNCSA-N Leu-Asp-Val Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O QCSFMCFHVGTLFF-NHCYSSNCSA-N 0.000 abstract 1
- 108010039491 Ricin Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 239000002619 cytotoxin Substances 0.000 abstract 1
- 108010083708 leucyl-aspartyl-valine Proteins 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Optics & Photonics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919116925A GB9116925D0 (en) | 1991-08-06 | 1991-08-06 | Novel reagent for tumour imaging and therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69214383D1 true DE69214383D1 (de) | 1996-11-14 |
| DE69214383T2 DE69214383T2 (de) | 1997-02-20 |
Family
ID=10699563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69214383T Expired - Fee Related DE69214383T2 (de) | 1991-08-06 | 1992-08-06 | Reagenz für Bilderzeugung und Therapie von Tumoren |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5628979A (de) |
| EP (1) | EP0527056B1 (de) |
| JP (1) | JPH07503702A (de) |
| AT (1) | ATE143813T1 (de) |
| DE (1) | DE69214383T2 (de) |
| DK (1) | DK0527056T3 (de) |
| ES (1) | ES2096040T3 (de) |
| GB (1) | GB9116925D0 (de) |
| GR (1) | GR3022264T3 (de) |
| WO (1) | WO1993002708A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610148A (en) * | 1991-01-18 | 1997-03-11 | University College London | Macroscopically oriented cell adhesion protein for wound treatment |
| US5629287A (en) * | 1991-01-18 | 1997-05-13 | University College London | Depot formulations |
| US5443815A (en) * | 1991-11-27 | 1995-08-22 | Diatech, Inc. | Technetium-99m labeled peptides for imaging |
| GB9116925D0 (en) * | 1991-08-06 | 1991-09-18 | Antisoma Ltd | Novel reagent for tumour imaging and therapy |
| US7097839B1 (en) | 1993-10-26 | 2006-08-29 | Thomas Jefferson University | ST receptor binding compounds and methods of using the same |
| IT1261386B (it) * | 1993-12-21 | 1996-05-20 | Sorin Biomedica Spa | Peptidi modificati con gruppo fosfinico per la marcatura con 99m-tc e 186-188-re o agenti paramagnetici. |
| US6576239B1 (en) * | 1996-09-10 | 2003-06-10 | The Burnham Institute | Angiogenic homing molecules and conjugates derived therefrom |
| US6418338B1 (en) | 1998-02-06 | 2002-07-09 | Phylatron Ltd. | Method for detecting and surgically removing lymphoid tissue involved in tumor progression |
| US20070231833A1 (en) * | 2005-05-23 | 2007-10-04 | Arcidiacono Steven M | Labeled antimicrobial peptides and method of using the same to detect microorganisms of interest |
| CN108976280B (zh) * | 2017-05-30 | 2021-09-24 | 首都医科大学 | 脂肪胺修饰的ldv,其合成,活性和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4691006A (en) * | 1983-03-04 | 1987-09-01 | Ohio State University | Antigenic modification of polypeptides |
| US4767842A (en) * | 1973-05-07 | 1988-08-30 | The Ohio State University | Antigenic modification of polypeptides |
| US5135736A (en) * | 1988-08-15 | 1992-08-04 | Neorx Corporation | Covalently-linked complexes and methods for enhanced cytotoxicity and imaging |
| AU5186090A (en) * | 1989-02-23 | 1990-09-26 | Colorado State University Research Foundation | Gnrh analogs for destroying gonadotrophs |
| GB8914020D0 (en) * | 1989-06-19 | 1989-08-09 | Antisoma Ltd | Synthetic peptides for use in thrombus detection |
| EP0428266B1 (de) * | 1989-10-13 | 1994-09-28 | Takara Shuzo Co. Ltd. | Antikrebsmittel |
| US5382569A (en) * | 1991-05-16 | 1995-01-17 | Warner-Lambert Company | Endotherlin antagonists |
| GB9116925D0 (en) * | 1991-08-06 | 1991-09-18 | Antisoma Ltd | Novel reagent for tumour imaging and therapy |
-
1991
- 1991-08-06 GB GB919116925A patent/GB9116925D0/en active Pending
-
1992
- 1992-08-06 US US08/190,130 patent/US5628979A/en not_active Expired - Lifetime
- 1992-08-06 DE DE69214383T patent/DE69214383T2/de not_active Expired - Fee Related
- 1992-08-06 AT AT92307198T patent/ATE143813T1/de not_active IP Right Cessation
- 1992-08-06 EP EP92307198A patent/EP0527056B1/de not_active Expired - Lifetime
- 1992-08-06 ES ES92307198T patent/ES2096040T3/es not_active Expired - Lifetime
- 1992-08-06 JP JP5503431A patent/JPH07503702A/ja active Pending
- 1992-08-06 WO PCT/GB1992/001458 patent/WO1993002708A1/en active Application Filing
- 1992-08-06 DK DK92307198.9T patent/DK0527056T3/da active
-
1997
- 1997-01-09 GR GR970400033T patent/GR3022264T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0527056B1 (de) | 1996-10-09 |
| US5628979A (en) | 1997-05-13 |
| JPH07503702A (ja) | 1995-04-20 |
| WO1993002708A1 (en) | 1993-02-18 |
| DE69214383T2 (de) | 1997-02-20 |
| GR3022264T3 (en) | 1997-04-30 |
| DK0527056T3 (da) | 1996-12-30 |
| GB9116925D0 (en) | 1991-09-18 |
| ES2096040T3 (es) | 1997-03-01 |
| EP0527056A1 (de) | 1993-02-10 |
| ATE143813T1 (de) | 1996-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ANTISOMA RESEARCH LTD., LONDON, GB |
|
| 8339 | Ceased/non-payment of the annual fee |