DE69133067D1 - Menschliche cyclin-a-zusammensetzungen, verfahren zu ihrer herstellung, nukleotidsequenz, verfahren und wirkstoffe zur bestimmung oder diagnose von zellvermehrung, verfahren und wirkstoffe zur hemmung der zellvermehrung - Google Patents

Menschliche cyclin-a-zusammensetzungen, verfahren zu ihrer herstellung, nukleotidsequenz, verfahren und wirkstoffe zur bestimmung oder diagnose von zellvermehrung, verfahren und wirkstoffe zur hemmung der zellvermehrung

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Publication number
DE69133067D1
DE69133067D1 DE69133067T DE69133067T DE69133067D1 DE 69133067 D1 DE69133067 D1 DE 69133067D1 DE 69133067 T DE69133067 T DE 69133067T DE 69133067 T DE69133067 T DE 69133067T DE 69133067 D1 DE69133067 D1 DE 69133067D1
Authority
DE
Germany
Prior art keywords
human cyclin
methods
active substances
cell reproduction
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69133067T
Other languages
English (en)
Other versions
DE69133067T2 (de
Inventor
Christian Brechot
Jian Wang
Xavier Chenivesse
Berthold Henglein
Frederique Zindy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Application granted granted Critical
Publication of DE69133067D1 publication Critical patent/DE69133067D1/de
Publication of DE69133067T2 publication Critical patent/DE69133067T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3513—Protein; Peptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69133067T 1990-02-12 1991-02-06 Menschliche cyclin-a-zusammensetzungen, verfahren zu ihrer herstellung, nukleotidsequenz, verfahren und wirkstoffe zur bestimmung oder diagnose von zellvermehrung, verfahren und wirkstoffe zur hemmung der zellvermehrung Expired - Lifetime DE69133067T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9001596A FR2658204A1 (fr) 1990-02-12 1990-02-12 Nouvelles compositions de cycline a humaine, sequence nucleotidique correspondante, et agents de detection ou de diagnostic de mutations hepatocellulaires induites par le virus hbv.
PCT/FR1991/000089 WO1991012324A1 (fr) 1990-02-12 1991-02-06 Nouvelles compositions de cycline a humaine et leur procede de production, sequence nucleotidique correspondante, procede et agents de detection ou de diagnostic de la proliferation cellulaire et procede et agents d'inhibition de la proliferation cellulaire

Publications (2)

Publication Number Publication Date
DE69133067D1 true DE69133067D1 (de) 2002-08-22
DE69133067T2 DE69133067T2 (de) 2003-05-08

Family

ID=9393594

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69133067T Expired - Lifetime DE69133067T2 (de) 1990-02-12 1991-02-06 Menschliche cyclin-a-zusammensetzungen, verfahren zu ihrer herstellung, nukleotidsequenz, verfahren und wirkstoffe zur bestimmung oder diagnose von zellvermehrung, verfahren und wirkstoffe zur hemmung der zellvermehrung

Country Status (7)

Country Link
US (2) US5849508A (de)
EP (1) EP0471804B1 (de)
AT (1) ATE220717T1 (de)
DE (1) DE69133067T2 (de)
ES (1) ES2181667T3 (de)
FR (1) FR2658204A1 (de)
WO (1) WO1991012324A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5449755A (en) * 1991-09-20 1995-09-12 Fred Hutchinson Cancer Research Center Human cyclin E
FR2712301A1 (fr) * 1993-11-10 1995-05-19 Inst Nat Sante Rech Med Séquence nucléotidique du promoteur de la cycline A humaine et séquences anti-sens y relatives.
GB0123856D0 (en) * 2001-10-05 2001-11-28 Amersham Pharm Biotech Uk Ltd Method for determining cell cycle position
JP2006504937A (ja) * 2002-10-31 2006-02-09 シェモメテック・アクティーゼルスカブ 粒子の評価方法
US20070105181A1 (en) * 2005-05-04 2007-05-10 Invitrogen Corporation Identification of cancer biomarkers and phosphorylated pdroteins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4544545A (en) * 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
WO1989005854A1 (en) * 1987-12-16 1989-06-29 Institut Pasteur A novel steroid/thyroid hormone receptor-related gene, which is inappropriately expressed in human heptocellular carcinoma, and which is a retinoic acid receptor

Also Published As

Publication number Publication date
EP0471804A1 (de) 1992-02-26
WO1991012324A1 (fr) 1991-08-22
FR2658204B1 (de) 1994-08-19
ES2181667T3 (es) 2003-03-01
EP0471804B1 (de) 2002-07-17
DE69133067T2 (de) 2003-05-08
ATE220717T1 (de) 2002-08-15
US5849508A (en) 1998-12-15
US6103887A (en) 2000-08-15
FR2658204A1 (fr) 1991-08-16

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