DE69130363T2 - Antibakterielle penemverbindungen - Google Patents

Antibakterielle penemverbindungen

Info

Publication number
DE69130363T2
DE69130363T2 DE69130363T DE69130363T DE69130363T2 DE 69130363 T2 DE69130363 T2 DE 69130363T2 DE 69130363 T DE69130363 T DE 69130363T DE 69130363 T DE69130363 T DE 69130363T DE 69130363 T2 DE69130363 T2 DE 69130363T2
Authority
DE
Germany
Prior art keywords
pct
ethyl
group
sec
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69130363T
Other languages
English (en)
Other versions
DE69130363D1 (de
Inventor
Hiromitsu Iwata
Takashi Nataksuka
Rie Tanaka
Masaji Ishiguro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daichi Suntory Pharma Co Ltd Tokio/tokyo Jp
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DE69130363D1 publication Critical patent/DE69130363D1/de
Publication of DE69130363T2 publication Critical patent/DE69130363T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
DE69130363T 1990-08-20 1991-08-16 Antibakterielle penemverbindungen Expired - Fee Related DE69130363T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21705390 1990-08-20
PCT/JP1991/001099 WO1992003443A1 (en) 1990-08-20 1991-08-16 Antibacterial penem compounds

Publications (2)

Publication Number Publication Date
DE69130363D1 DE69130363D1 (de) 1998-11-19
DE69130363T2 true DE69130363T2 (de) 1999-04-22

Family

ID=16698092

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130363T Expired - Fee Related DE69130363T2 (de) 1990-08-20 1991-08-16 Antibakterielle penemverbindungen

Country Status (10)

Country Link
US (1) US5506225A (de)
EP (1) EP0544905B1 (de)
JP (1) JP3148235B2 (de)
KR (1) KR0177844B1 (de)
AT (1) ATE172202T1 (de)
CA (1) CA2089369C (de)
DE (1) DE69130363T2 (de)
ES (1) ES2123512T3 (de)
IE (1) IE912910A1 (de)
WO (1) WO1992003443A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080940A1 (es) * 2006-06-28 2008-07-09 Pfizer Prod Inc Profarmacos de penem
CN101868460A (zh) * 2007-11-23 2010-10-20 国际药品工业株式会社 2-芳基甲基吖丁啶-碳青霉烯-3-羧酸酯衍生物或其盐、其制备方法以及包含上述的药物组合物
EP3693374B1 (de) * 2017-10-05 2022-01-26 FUJIFILM Corporation Neue 2-carboxypenam-verbindung oder ein salz davon, diese verbindung oder salz enthaltende pharmazeutische zusammensetzung und verwendung davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619783A (en) * 1983-06-10 1986-10-28 Pfizer Inc. Process and intermediates for the preparation of penem derivatives
JPH075463B2 (ja) * 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
EP0275002A1 (de) * 1987-01-09 1988-07-20 Hoechst Aktiengesellschaft Verfahren zur Herstellung von 7-Oxo-4-thia-1-aza-bicyclo[3.2.0]-hept-2-en-Derivaten
GB8713515D0 (en) * 1987-06-10 1987-07-15 Erba Farmitalia Methoxymethyl compounds
GB8714413D0 (en) * 1987-06-19 1987-07-22 Erba Farmitalia 6-substituted penem esters
GB2220203B (en) * 1988-07-04 1991-09-11 Erba Carlo Spa Process for penems
EP0399228A1 (de) * 1989-04-29 1990-11-28 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Penemverbindungen
JP2992314B2 (ja) * 1989-07-26 1999-12-20 サントリー株式会社 アリル基の除去方法

Also Published As

Publication number Publication date
ATE172202T1 (de) 1998-10-15
ES2123512T3 (es) 1999-01-16
JPH06504760A (ja) 1994-06-02
KR0177844B1 (ko) 1999-03-20
DE69130363D1 (de) 1998-11-19
KR930701453A (ko) 1993-06-11
US5506225A (en) 1996-04-09
EP0544905B1 (de) 1998-10-14
IE912910A1 (en) 1992-02-26
CA2089369C (en) 2002-10-08
WO1992003443A1 (en) 1992-03-05
CA2089369A1 (en) 1992-02-21
JP3148235B2 (ja) 2001-03-19
EP0544905A1 (de) 1993-06-09

Similar Documents

Publication Publication Date Title
HU9302795D0 (en) Fungide compositions containing 2-(substituted phenyl)-ester of 3-metoxi-propenoic acid
AU3113695A (en) Distamycin a analogues as antitumour or antiviral agents
BR0311771A (pt) Derivados de nonano e azabiciclo-octano com atividade inibitória da ddp-iv
BR9105062A (pt) Processo de preparacao de compostos
DE59510246D1 (de) Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
BR1100412A (pt) Composto; método para propiciar tratamento imunomodulador; e composição farmacêutica para tratamento imunomodulador
GR3020853T3 (en) Macrocyclic lactam prokinetic agents
HRP950115B1 (en) The use of carboxylic acid derivatives as medicaments
GR3035449T3 (en) Novel silyl compounds and their use
ATE172202T1 (de) Antibakterielle penemverbindungen
TW252979B (de)
DE69132580T2 (de) 7-Acyl-3-(substituierte carbamoyloxy) Cephem Verbindungen, Verfahren zu ihrer Herstellung und Anwendung
HRP950437A2 (en) N-substituted azabicycloheptane derivatives, their production and use
ZA942964B (en) Pyrrolopyrazine compounds processes for their preparation and the pharmaceutical compositions which contain them
AU8333991A (en) Penem compounds
ES2121058T3 (es) Compuestos antibioticos de carbapenem.
IL99369A0 (en) Pharmaceutical compositions containing substituted 2-cyclohexene derivatives
TH13040EX (th) คาร์บาพีเนม ซึ่งมีหมู่เฟนิลที่ถูกแทนที่ด้วย หมู่คาร์บอกซิ, กรรมวิธีสำหรับเตรียมสารเหล่านั้น สารขั้นกลางการใช้เป็นสารปฏิชีวนะ

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DAICHI SUNTORY PHARMA CO., LTD., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee