DE69130235D1 - Rezeptor-konjugate zum targeting von arzneiwirkstoffen und anderen wirksubstanzen - Google Patents

Rezeptor-konjugate zum targeting von arzneiwirkstoffen und anderen wirksubstanzen

Info

Publication number
DE69130235D1
DE69130235D1 DE69130235T DE69130235T DE69130235D1 DE 69130235 D1 DE69130235 D1 DE 69130235D1 DE 69130235 T DE69130235 T DE 69130235T DE 69130235 T DE69130235 T DE 69130235T DE 69130235 D1 DE69130235 D1 DE 69130235D1
Authority
DE
Germany
Prior art keywords
targeting
active substances
medicinal agents
conjugates
receptor conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69130235T
Other languages
English (en)
Other versions
DE69130235T2 (de
Inventor
Howard Krivan
Arne Blomberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emergent Product Development Gaithersburg Inc
Original Assignee
Antex Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antex Biologics Inc filed Critical Antex Biologics Inc
Application granted granted Critical
Publication of DE69130235D1 publication Critical patent/DE69130235D1/de
Publication of DE69130235T2 publication Critical patent/DE69130235T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69130235T 1991-07-31 1991-07-31 Rezeptor-konjugate zum targeting von arzneiwirkstoffen und anderen wirksubstanzen Expired - Fee Related DE69130235T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002114629A CA2114629C (en) 1991-07-31 1991-07-31 Receptor conjugates for targeting antibiotics to bacteria
PCT/US1991/005422 WO1993002709A1 (en) 1991-07-31 1991-07-31 Receptor conjugates for targeting drugs and other agents

Publications (2)

Publication Number Publication Date
DE69130235D1 true DE69130235D1 (de) 1998-10-22
DE69130235T2 DE69130235T2 (de) 1999-02-11

Family

ID=25676975

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130235T Expired - Fee Related DE69130235T2 (de) 1991-07-31 1991-07-31 Rezeptor-konjugate zum targeting von arzneiwirkstoffen und anderen wirksubstanzen

Country Status (8)

Country Link
EP (1) EP0598719B1 (de)
JP (1) JP3369555B2 (de)
AT (1) ATE171072T1 (de)
CA (1) CA2114629C (de)
DE (1) DE69130235T2 (de)
DK (1) DK0598719T3 (de)
ES (1) ES2123514T3 (de)
WO (1) WO1993002709A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
JPH08133971A (ja) * 1994-09-16 1996-05-28 Toyama Chem Co Ltd 抗ヘリコバクター剤
WO1997041840A1 (en) * 1996-05-03 1997-11-13 Cubicciotti Roger S Prodrug compositions and drug delivery methods using synthetic receptors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1165238A (en) * 1980-03-12 1984-04-10 Demetrios P. Papahadjopoulos Activated liposomes and method
SE8501613D0 (sv) * 1985-04-01 1985-04-01 Bio Carb Ab Foreningar for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutisk behandling
GB8628398D0 (en) * 1986-11-27 1986-12-31 Central Blood Lab Authority Pharmaceutically-active conjugates
DE3711724A1 (de) * 1987-04-07 1988-10-20 Harro Boerner Medizinische Kom System zum einwirken auf, insbesondere zerstoeren von viren
WO1989001519A1 (en) * 1987-08-20 1989-02-23 Children's Hospital Corporation Human mannose binding protein
CA2017739A1 (en) * 1989-07-18 1991-01-18 Leslie S. Hollis Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents
WO1991005771A1 (en) * 1989-10-13 1991-05-02 Hans Schreier Lipophilic acylpyrazinamide prodrugs

Also Published As

Publication number Publication date
DK0598719T3 (da) 1999-06-14
EP0598719B1 (de) 1998-09-16
CA2114629A1 (en) 1993-02-18
EP0598719A1 (de) 1994-06-01
DE69130235T2 (de) 1999-02-11
ES2123514T3 (es) 1999-01-16
JP3369555B2 (ja) 2003-01-20
JPH06511466A (ja) 1994-12-22
ATE171072T1 (de) 1998-10-15
WO1993002709A1 (en) 1993-02-18
CA2114629C (en) 2003-01-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee