DE69129760D1 - T-cadherin-bindungsmolekül - Google Patents

T-cadherin-bindungsmolekül

Info

Publication number
DE69129760D1
DE69129760D1 DE69129760T DE69129760T DE69129760D1 DE 69129760 D1 DE69129760 D1 DE 69129760D1 DE 69129760 T DE69129760 T DE 69129760T DE 69129760 T DE69129760 T DE 69129760T DE 69129760 D1 DE69129760 D1 DE 69129760D1
Authority
DE
Germany
Prior art keywords
cadherin
binding molecule
various forms
polypeptides
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69129760T
Other languages
English (en)
Other versions
DE69129760T2 (de
Inventor
Barbara Ranscht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanford Burnham Prebys Medical Discovery Institute
Original Assignee
Sanford Burnham Prebys Medical Discovery Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanford Burnham Prebys Medical Discovery Institute filed Critical Sanford Burnham Prebys Medical Discovery Institute
Publication of DE69129760D1 publication Critical patent/DE69129760D1/de
Application granted granted Critical
Publication of DE69129760T2 publication Critical patent/DE69129760T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69129760T 1990-10-30 1991-10-30 T-cadherin-bindungsmolekül Expired - Fee Related DE69129760T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60729390A 1990-10-30 1990-10-30
PCT/US1991/008022 WO1992008731A2 (en) 1990-10-30 1991-10-30 T-cadherin adhesion molecule

Publications (2)

Publication Number Publication Date
DE69129760D1 true DE69129760D1 (de) 1998-08-13
DE69129760T2 DE69129760T2 (de) 1999-03-25

Family

ID=24431648

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69129760T Expired - Fee Related DE69129760T2 (de) 1990-10-30 1991-10-30 T-cadherin-bindungsmolekül

Country Status (8)

Country Link
US (4) US5585351A (de)
EP (1) EP0619841B1 (de)
JP (1) JPH06505962A (de)
AT (1) ATE168131T1 (de)
AU (1) AU669474B2 (de)
CA (1) CA2095115A1 (de)
DE (1) DE69129760T2 (de)
WO (1) WO1992008731A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06505962A (ja) * 1990-10-30 1994-07-07 ラ　ホヤ　キャンサー　リサーチ　ファウンデーション Ｔ−カドヘリン接着分子
US5597725A (en) * 1992-04-17 1997-01-28 Doheny Eye Institute Cadherin-specific antibodies and hybridoma cell lines
US5646250A (en) * 1992-04-17 1997-07-08 Doheny Eye Institute Cadherin polypeptides
EP2325203A2 (de) 1992-04-17 2011-05-25 Doheny Eye Institute Materialien und Methoden zur Herstellung von Cadherinen
US5798224A (en) 1992-12-29 1998-08-25 Doheny Eye Institute Nucleic acids encoding protocadherin
US5643781A (en) * 1992-12-29 1997-07-01 Doheny Eye Institute DNA encoding protocadherin-42
US6610821B1 (en) 1996-07-12 2003-08-26 Mcgill University Compounds and methods for modulating endothelial cell adhesion
US20040006011A1 (en) * 1996-07-12 2004-01-08 Gour Barbara J. Peptidomimetic modulators of cell adhesion
US6207639B1 (en) 1996-07-12 2001-03-27 Mcgill University Compounds and methods for modulating neurite outgrowth
US7122623B2 (en) 1996-07-12 2006-10-17 Adherex Technologies, Inc. Compounds and methods for modulating cell adhesion
EP0937103B1 (de) 1996-07-12 2007-11-28 McGILL UNIVERSITY Verbindungen und verfahren zur regulierung der zellanlagerung
US6465427B1 (en) 1996-07-12 2002-10-15 Mcgill University Compounds and methods for modulating cell adhesion
US6169071B1 (en) 1996-07-12 2001-01-02 Mcgill University Compounds and methods for modulating cell adhesion
US6562786B1 (en) 1996-07-12 2003-05-13 Mcgill University Compounds and methods for modulating apoptosis
US6417325B1 (en) 1996-07-12 2002-07-09 Mcgill University Compounds and methods for cancer therapy
US6333307B1 (en) 1996-07-12 2001-12-25 Mcgill University Compounds and method for modulating neurite outgrowth
US6346512B1 (en) 1996-07-12 2002-02-12 Mcgill University Compounds and methods for modulating cell adhesion
US6203788B1 (en) 1997-09-29 2001-03-20 Adherex Inc. Compounds and methods for regulating cell adhesion
US6472367B1 (en) 1998-05-05 2002-10-29 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin mediated cell adhesion
US6638911B1 (en) 1998-05-05 2003-10-28 Adherex Technologies Inc. Compounds and methods for modulating desmosomal cadherin-mediated functions
US7481999B2 (en) * 1998-05-05 2009-01-27 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin-mediated function
US6680175B2 (en) * 1998-05-05 2004-01-20 Adherex Technologies, Inc. Methods for diagnosing and evaluating cancer
US20050203025A1 (en) * 1998-05-05 2005-09-15 Adherex Technologies, Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US6277824B1 (en) * 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
US7041807B1 (en) 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
WO2001062206A2 (en) * 2000-02-22 2001-08-30 Mount Sinai School Of Medicine Of New York University N-cadherin modulated migration, invasion, and metastasis
US20040072236A1 (en) 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
EP1560850A2 (de) * 2002-11-14 2005-08-10 Adherex Technologies, Inc. Verbindungen und verfahren zur regulierung der durch desmosomale und atypische cadherine vermittelten zelladhäsion
US20060286035A1 (en) * 2003-04-29 2006-12-21 Cytos Biotechnology Ag Methods and compositions for modulating the interaction between adiponectin and its receptor
US20090123471A1 (en) * 2004-10-29 2009-05-14 Cytos Biotechnology Ag T-Cadherin antigen arrays and uses thereof
KR100990027B1 (ko) * 2005-04-26 2010-10-26 화이자 인코포레이티드 Ｐ-카드헤린 항체
US20060292159A1 (en) * 2005-06-08 2006-12-28 Ranscht Barbara E Methods for the inhibition of neovascularization and cancer metastasis
US9534058B2 (en) 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06505962A (ja) * 1990-10-30 1994-07-07 ラ　ホヤ　キャンサー　リサーチ　ファウンデーション Ｔ−カドヘリン接着分子

Also Published As

Publication number Publication date
US5585351A (en) 1996-12-17
WO1992008731A2 (en) 1992-05-29
AU8953191A (en) 1992-06-11
JPH06505962A (ja) 1994-07-07
WO1992008731A3 (en) 1992-06-25
ATE168131T1 (de) 1998-07-15
US5811518A (en) 1998-09-22
EP0619841A4 (de) 1994-05-17
CA2095115A1 (en) 1992-05-01
US5837525A (en) 1998-11-17
AU669474B2 (en) 1996-06-13
EP0619841A1 (de) 1994-10-19
US5863804A (en) 1999-01-26
DE69129760T2 (de) 1999-03-25
EP0619841B1 (de) 1998-07-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee