DE69120386T2 - Mikrofluss-Prozessor - Google Patents

Mikrofluss-Prozessor

Info

Publication number
DE69120386T2
DE69120386T2 DE69120386T DE69120386T DE69120386T2 DE 69120386 T2 DE69120386 T2 DE 69120386T2 DE 69120386 T DE69120386 T DE 69120386T DE 69120386 T DE69120386 T DE 69120386T DE 69120386 T2 DE69120386 T2 DE 69120386T2
Authority
DE
Germany
Prior art keywords
mfp
micro
flow rates
reproducible
flow processor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69120386T
Other languages
English (en)
Other versions
DE69120386D1 (de
Inventor
Jean-Pierre Chervet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LC PACKINGS NEDERLAND BV
Original Assignee
LC PACKINGS NEDERLAND BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LC PACKINGS NEDERLAND BV filed Critical LC PACKINGS NEDERLAND BV
Application granted granted Critical
Publication of DE69120386D1 publication Critical patent/DE69120386D1/de
Publication of DE69120386T2 publication Critical patent/DE69120386T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G01N2030/347—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient mixers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/10—Preparation using a splitter
DE69120386T 1991-01-17 1991-01-17 Mikrofluss-Prozessor Expired - Lifetime DE69120386T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91200080A EP0495255B1 (de) 1991-01-17 1991-01-17 Mikrofluss-Prozessor

Publications (2)

Publication Number Publication Date
DE69120386D1 DE69120386D1 (de) 1996-07-25
DE69120386T2 true DE69120386T2 (de) 1996-10-31

Family

ID=8207498

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69120386T Expired - Lifetime DE69120386T2 (de) 1991-01-17 1991-01-17 Mikrofluss-Prozessor

Country Status (3)

Country Link
EP (1) EP0495255B1 (de)
AT (1) ATE139625T1 (de)
DE (1) DE69120386T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112004002321B4 (de) 2003-11-26 2022-05-25 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Vorrichtung zum Ausbilden einer Gradientenzusammensetzung in einem Kapillarsystem sowie Vorrichtung zum Messen von Flussraten einer Flüssigkeit in einem Kapillarsystem

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0686848A1 (de) * 1994-05-09 1995-12-13 Shiseido Company Limited Flüssigchromatograph mit Mikro- oder Halbmikrokolonne
DE19728520A1 (de) * 1997-07-04 1999-01-07 Imb Inst Fuer Molekulare Biote Schaltbarer dynamischer Mikromischer mit minimalem Totvolumen
WO2000072001A1 (fr) * 1999-05-19 2000-11-30 Eisai Co., Ltd. Distributeur pour chromatographie en phase liquide haute performance a gradient
US6289914B1 (en) 2000-08-16 2001-09-18 Novartis Ag Microflow splitter
JP3764421B2 (ja) 2000-10-03 2006-04-05 ダイオネックス コーポレイション 液体クロマトグラフィ−質量分析計（ｌｃ−ｍｓ）分析におけるピークパーキングのための方法及びシステム
DE50111054D1 (de) 2001-12-21 2006-11-02 Agilent Technologies Inc Verfahren zur Bereitstellung von Volumenströmen von Fluiden
US6813929B2 (en) 2002-08-01 2004-11-09 Dionex Corporation Method and apparatus for monitoring fluid flow
DE10360964B4 (de) * 2003-12-23 2005-12-01 Dionex Softron Gmbh Verfahren und Vorrichtung zur Bereitstellung eines definierten Fluidstroms, insbesondere für die Flüssigkeitschromatographie
US7624626B2 (en) 2005-11-17 2009-12-01 Aim Research Co. Dynamic flow liquid chromatography
US7998418B1 (en) 2006-06-01 2011-08-16 Nanotek, Llc Evaporator and concentrator in reactor and loading system
US9354208B2 (en) 2009-01-22 2016-05-31 Agilent Technologies, Inc. Apparatus for generating small flow rates in a channel
CN102821856A (zh) * 2010-03-31 2012-12-12 通用电气健康护理生物科学股份公司 并行分离系统
CN108956788B (zh) 2011-03-23 2022-08-02 明尼苏达大学评议会 用于多维液体分析的阀和分流系统
EP2626697B1 (de) * 2012-02-07 2018-10-31 King Saud University Flüssigchromatografievorrichtung
US9683975B2 (en) 2014-02-12 2017-06-20 Idex Health & Science Llc Volumetric flow regulation in multi-dimensional liquid analysis systems

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035168A (en) * 1974-07-24 1977-07-12 The Regents Of The University Of California Nonreactive inlet splitter for gas chromatography and method
NL7801663A (en) * 1977-02-15 1978-08-17 Tracor Appts. for mixing solvents for chromatography - using means for regulating the proportions in the mixt. according to predetermined programme

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112004002321B4 (de) 2003-11-26 2022-05-25 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Vorrichtung zum Ausbilden einer Gradientenzusammensetzung in einem Kapillarsystem sowie Vorrichtung zum Messen von Flussraten einer Flüssigkeit in einem Kapillarsystem

Also Published As

Publication number Publication date
ATE139625T1 (de) 1996-07-15
EP0495255A1 (de) 1992-07-22
EP0495255B1 (de) 1996-06-19
DE69120386D1 (de) 1996-07-25

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