DE69117899T2 - 4-Hydroxypyridinderivat, Verfahren zu dessen Herstellung sowie dieses enthaltendes pharmazeutisches Mittel - Google Patents

4-Hydroxypyridinderivat, Verfahren zu dessen Herstellung sowie dieses enthaltendes pharmazeutisches Mittel

Info

Publication number
DE69117899T2
DE69117899T2 DE69117899T DE69117899T DE69117899T2 DE 69117899 T2 DE69117899 T2 DE 69117899T2 DE 69117899 T DE69117899 T DE 69117899T DE 69117899 T DE69117899 T DE 69117899T DE 69117899 T2 DE69117899 T2 DE 69117899T2
Authority
DE
Germany
Prior art keywords
preparation
agent containing
pharmaceutical agent
hydroxypyridine derivative
hydroxypyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69117899T
Other languages
English (en)
Other versions
DE69117899D1 (de
Inventor
Shin-Ichi Hirano
Yoshio Watanabe
Kaichiro Kominato
Naoki Agata
Yutaka Hara
Norio Shibamoto
Takeo Yoshioka
Tomoyuki Kioka
Hiroshi Iguchi
Masataka Shirai
Hiroshi Tone
Rokuro Okamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mercian Corp
Original Assignee
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mercian Corp filed Critical Mercian Corp
Application granted granted Critical
Publication of DE69117899D1 publication Critical patent/DE69117899D1/de
Publication of DE69117899T2 publication Critical patent/DE69117899T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
DE69117899T 1990-12-14 1991-12-12 4-Hydroxypyridinderivat, Verfahren zu dessen Herstellung sowie dieses enthaltendes pharmazeutisches Mittel Expired - Fee Related DE69117899T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2410526A JPH04210679A (ja) 1990-12-14 1990-12-14 Mer−A2026A物質およびB物質、その製造方法およびその物質を有効成分とする血管拡張剤

Publications (2)

Publication Number Publication Date
DE69117899D1 DE69117899D1 (de) 1996-04-18
DE69117899T2 true DE69117899T2 (de) 1996-10-02

Family

ID=18519683

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69117899T Expired - Fee Related DE69117899T2 (de) 1990-12-14 1991-12-12 4-Hydroxypyridinderivat, Verfahren zu dessen Herstellung sowie dieses enthaltendes pharmazeutisches Mittel

Country Status (4)

Country Link
US (1) US5223519A (de)
EP (1) EP0491281B1 (de)
JP (1) JPH04210679A (de)
DE (1) DE69117899T2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019198825A1 (ja) * 2018-04-13 2019-10-17 国立大学法人京都大学 微生物由来化合物を用いたアルツハイマー病の予防、治療、または診断薬
CN113402453B (zh) * 2021-06-21 2022-08-05 中国科学院南海海洋研究所 一种吡啶酮粉蝶霉素及其制备方法和在制备抗癌药物中的应用

Also Published As

Publication number Publication date
US5223519A (en) 1993-06-29
EP0491281B1 (de) 1996-03-13
DE69117899D1 (de) 1996-04-18
EP0491281A1 (de) 1992-06-24
JPH04210679A (ja) 1992-07-31

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8339 Ceased/non-payment of the annual fee