DE69031797D1 - Promoterregionen der Gene, die für die Pilus-Untereinheiten fim2, fim3 und fimx von Bordetella pertussis kodieren und ihre Verwendung bei der Expression von Genen, die für ein interessierendes Protein kodieren - Google Patents
Promoterregionen der Gene, die für die Pilus-Untereinheiten fim2, fim3 und fimx von Bordetella pertussis kodieren und ihre Verwendung bei der Expression von Genen, die für ein interessierendes Protein kodierenInfo
- Publication number
- DE69031797D1 DE69031797D1 DE69031797T DE69031797T DE69031797D1 DE 69031797 D1 DE69031797 D1 DE 69031797D1 DE 69031797 T DE69031797 T DE 69031797T DE 69031797 T DE69031797 T DE 69031797T DE 69031797 D1 DE69031797 D1 DE 69031797D1
- Authority
- DE
- Germany
- Prior art keywords
- genes encoding
- promoter regions
- fimx
- fim3
- fim2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 108700039691 Genetic Promoter Regions Proteins 0.000 title abstract 3
- UTPGRZGMQVAYAA-UHFFFAOYSA-N 4-fluoro-n-methyl-n-[4-[6-(methylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]benzamide Chemical compound C1=NC(NC)=CC(C=2N=C(SC=2)N(C)C(=O)C=2C=CC(F)=CC=2)=N1 UTPGRZGMQVAYAA-UHFFFAOYSA-N 0.000 title abstract 2
- 241000588832 Bordetella pertussis Species 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 241000588807 Bordetella Species 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 238000012512 characterization method Methods 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229940066827 pertussis vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02225289A IT1236971B (it) | 1989-11-03 | 1989-11-03 | Regione promotore dei geni codificanti le subunita' piliniche fim2, fm3 e fimx di bordetella pertussis e loro impiego per l'espressione di geni che codificano una proteina di interesse. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69031797D1 true DE69031797D1 (de) | 1998-01-22 |
| DE69031797T2 DE69031797T2 (de) | 1998-04-09 |
Family
ID=11193695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69031797T Expired - Fee Related DE69031797T2 (de) | 1989-11-03 | 1990-10-29 | Promoterregionen der Gene, die für die Pilus-Untereinheiten fim2, fim3 und fimx von Bordetella pertussis kodieren und ihre Verwendung bei der Expression von Genen, die für ein interessierendes Protein kodieren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5395764A (de) |
| EP (1) | EP0426059B1 (de) |
| AT (1) | ATE161047T1 (de) |
| CA (1) | CA2029146A1 (de) |
| DE (1) | DE69031797T2 (de) |
| DK (1) | DK0426059T3 (de) |
| ES (1) | ES2112248T3 (de) |
| IT (1) | IT1236971B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9008746D0 (en) * | 1990-04-18 | 1990-06-13 | Connaught Lab | The use of autologous promoters to express gene products in bordetella |
| US5932714A (en) * | 1995-02-23 | 1999-08-03 | Connaught Laboratories Limited | Expression of gene products from genetically manipulated strains of Bordetella |
| US5998168A (en) * | 1995-06-07 | 1999-12-07 | Connaught Laboratories Limited | Expression of gene products from genetically manipulated strains of bordetella |
| SG11202003333WA (en) * | 2017-10-18 | 2020-05-28 | Pasteur Institut | Bordetella strains expressing serotype 3 fimbriae |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4338299A (en) * | 1980-11-17 | 1982-07-06 | Dso "Pharmachim" | Vaccine against pertussis |
| JP2537042B2 (ja) * | 1986-11-27 | 1996-09-25 | 社団法人北里研究所 | ボルデテラ・ブロンキセプチカ感染症生菌ワクチン用原株の製造法および生菌ワクチン |
| IT1223579B (it) * | 1987-12-22 | 1990-09-19 | Eniricerche Spa | Clonaggio e sequenziamento del gene codificante per una nuova subunita' pilinica di bordetella pertussis |
-
1989
- 1989-11-03 IT IT02225289A patent/IT1236971B/it active IP Right Grant
-
1990
- 1990-10-29 EP EP90120679A patent/EP0426059B1/de not_active Expired - Lifetime
- 1990-10-29 DK DK90120679.7T patent/DK0426059T3/da active
- 1990-10-29 DE DE69031797T patent/DE69031797T2/de not_active Expired - Fee Related
- 1990-10-29 ES ES90120679T patent/ES2112248T3/es not_active Expired - Lifetime
- 1990-10-29 AT AT90120679T patent/ATE161047T1/de not_active IP Right Cessation
- 1990-11-01 CA CA002029146A patent/CA2029146A1/en not_active Abandoned
-
1994
- 1994-03-16 US US08/213,811 patent/US5395764A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK0426059T3 (da) | 1998-01-12 |
| EP0426059B1 (de) | 1997-12-10 |
| IT1236971B (it) | 1993-05-07 |
| ES2112248T3 (es) | 1998-04-01 |
| EP0426059A1 (de) | 1991-05-08 |
| IT8922252A1 (it) | 1991-05-03 |
| CA2029146A1 (en) | 1991-05-04 |
| DE69031797T2 (de) | 1998-04-09 |
| IT8922252A0 (it) | 1989-11-03 |
| US5395764A (en) | 1995-03-07 |
| ATE161047T1 (de) | 1997-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |