DE69022314T2 - Stabile emulgierte Tretinoin-Cremeformulierungen. - Google Patents

Stabile emulgierte Tretinoin-Cremeformulierungen.

Info

Publication number
DE69022314T2
DE69022314T2 DE69022314T DE69022314T DE69022314T2 DE 69022314 T2 DE69022314 T2 DE 69022314T2 DE 69022314 T DE69022314 T DE 69022314T DE 69022314 T DE69022314 T DE 69022314T DE 69022314 T2 DE69022314 T2 DE 69022314T2
Authority
DE
Germany
Prior art keywords
tretinoin
cream formulations
stable emulsified
tretinoin cream
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69022314T
Other languages
English (en)
Other versions
DE69022314D1 (de
Inventor
Prakash Parab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE69022314D1 publication Critical patent/DE69022314D1/de
Application granted granted Critical
Publication of DE69022314T2 publication Critical patent/DE69022314T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
DE69022314T 1989-07-13 1990-07-12 Stabile emulgierte Tretinoin-Cremeformulierungen. Expired - Fee Related DE69022314T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37929489A 1989-07-13 1989-07-13
US45364089A 1989-12-20 1989-12-20

Publications (2)

Publication Number Publication Date
DE69022314D1 DE69022314D1 (de) 1995-10-19
DE69022314T2 true DE69022314T2 (de) 1996-03-14

Family

ID=27008559

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022314T Expired - Fee Related DE69022314T2 (de) 1989-07-13 1990-07-12 Stabile emulgierte Tretinoin-Cremeformulierungen.

Country Status (10)

Country Link
EP (1) EP0408370B1 (de)
JP (1) JPH03128307A (de)
KR (1) KR920007567B1 (de)
AT (1) ATE127683T1 (de)
AU (1) AU621763B2 (de)
CA (1) CA2020877C (de)
DE (1) DE69022314T2 (de)
FI (1) FI903483A0 (de)
IE (1) IE902550A1 (de)
PT (1) PT94687A (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559149A (en) 1990-01-29 1996-09-24 Johnson & Johnson Consumer Products, Inc. Skin care compositions containing retinoids
SI0706370T2 (en) † 1993-07-01 2005-06-30 Yamanouchi Europe B.V. Stable topical retinoid compositions
US5420106A (en) * 1994-03-22 1995-05-30 Bristol-Myers Squibb Company Method and composition having enhanced alpha-hydroxy acid skin permeation and retention
FR2717686B1 (fr) * 1994-03-22 1996-06-28 Fabre Pierre Cosmetique Composition dermo-cosmétologique et procédé de préparation.
US6461622B2 (en) 1994-09-07 2002-10-08 Johnson & Johnson Consumer Companies, Inc. Topical compositions
US6068847A (en) * 1996-10-03 2000-05-30 Johnson & Johnson Consumer Products, Inc. Cosmetic compositions
USH2043H1 (en) * 1997-05-23 2002-08-06 The Procter & Gamble Company Skin care compositions
JP3634139B2 (ja) * 1998-02-10 2005-03-30 株式会社資生堂 水中油型乳化組成物
WO1999040887A1 (fr) * 1998-02-10 1999-08-19 Shiseido Company, Ltd. Composition emulsionnees de type aqueux
US6531141B1 (en) 2000-03-07 2003-03-11 Ortho-Mcneil Pharmaceutical, Inc. Oil-in-water emulsion containing tretinoin
FR2857266B1 (fr) * 2003-07-07 2007-09-21 Jean Noel Thorel Composition a usage dermatologique et/ou cosmetique, comprenant a titre de principe actif au moins un antioxydant lipophile
FR2925313A1 (fr) * 2007-12-19 2009-06-26 Oreal Utilisation cosmetique de proteines de type plakoglobine
EP2149364A1 (de) * 2008-07-24 2010-02-03 Rohm and Haas Company Verfahren zur Minderung des Geruchs in Körperpflegeprodukten
CA2928962A1 (en) * 2013-10-28 2015-05-07 Morten SLOTH WEIDNER Dermatological compositions
KR101736478B1 (ko) 2017-01-10 2017-05-29 (주)씨드그룹 여드름 치료에 효능이 있는 로션 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL257621A (de) * 1959-11-23
US3966967A (en) * 1973-03-21 1976-06-29 The Regents Of The University Of California Compositions and methods of treating psoriasis with vinyligs of desmethyl retinoic acid
US3906108A (en) * 1973-10-12 1975-09-16 Johnson & Johnson Stabilized tretinoin cream emulsion
GB1466062A (en) * 1974-04-09 1977-03-02 Knight K Cosmetic preparations
US4678663A (en) * 1984-02-06 1987-07-07 Nuetrogena Corporation Hydroquinone composition having enhanced bio-availability and percutaneous adsorption
DE68902792T2 (de) * 1988-06-13 1993-04-15 Paul Herzog Mittel zur kosmetischen oder pharmazeutischen verwendung.
GB8821129D0 (en) * 1988-09-09 1988-10-12 Unilever Plc Cosmetic composition

Also Published As

Publication number Publication date
EP0408370A3 (de) 1991-03-13
FI903483A0 (fi) 1990-07-10
CA2020877C (en) 1995-04-25
AU5895990A (en) 1991-01-17
KR910002435A (ko) 1991-02-25
EP0408370B1 (de) 1995-09-13
IE902550A1 (en) 1991-02-27
DE69022314D1 (de) 1995-10-19
PT94687A (pt) 1991-03-20
ATE127683T1 (de) 1995-09-15
KR920007567B1 (ko) 1992-09-07
AU621763B2 (en) 1992-03-19
JPH03128307A (ja) 1991-05-31
EP0408370A2 (de) 1991-01-16
CA2020877A1 (en) 1991-01-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee