DE69012572T2 - Monoklonaler antikörper gegen acetylierte lysinabfälle in rekombinantem rindsomatotropin. - Google Patents
Monoklonaler antikörper gegen acetylierte lysinabfälle in rekombinantem rindsomatotropin.Info
- Publication number
- DE69012572T2 DE69012572T2 DE69012572T DE69012572T DE69012572T2 DE 69012572 T2 DE69012572 T2 DE 69012572T2 DE 69012572 T DE69012572 T DE 69012572T DE 69012572 T DE69012572 T DE 69012572T DE 69012572 T2 DE69012572 T2 DE 69012572T2
- Authority
- DE
- Germany
- Prior art keywords
- somatotropine
- rind
- recombinant
- acetylated lysine
- monoclonal antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004472 Lysine Substances 0.000 title abstract 2
- 241000283690 Bos taurus Species 0.000 title 1
- 239000002699 waste material Substances 0.000 title 1
- BJTZATWAPRKXBV-MRVPVSSYSA-N (2r)-2-acetyl-2,6-diaminohexanoic acid Chemical group CC(=O)[C@@](N)(C(O)=O)CCCCN BJTZATWAPRKXBV-MRVPVSSYSA-N 0.000 abstract 1
- JFCBEFFZEOHJDG-MLWJPKLSSA-N (2s)-2,6-diamino-7-oxooctanoic acid Chemical compound CC(=O)C(N)CCC[C@H](N)C(O)=O JFCBEFFZEOHJDG-MLWJPKLSSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38983389A | 1989-08-04 | 1989-08-04 | |
| PCT/US1990/003879 WO1991002080A2 (en) | 1989-08-04 | 1990-07-16 | Monoclonal antibody to acetylated lysine residues in recombinant bovine somatotropin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69012572D1 DE69012572D1 (de) | 1994-10-20 |
| DE69012572T2 true DE69012572T2 (de) | 1995-02-02 |
Family
ID=23539903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69012572T Expired - Fee Related DE69012572T2 (de) | 1989-08-04 | 1990-07-16 | Monoklonaler antikörper gegen acetylierte lysinabfälle in rekombinantem rindsomatotropin. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5849499A (de) |
| EP (1) | EP0485525B1 (de) |
| JP (1) | JPH05500007A (de) |
| AT (1) | ATE111531T1 (de) |
| AU (1) | AU6422990A (de) |
| CA (1) | CA2062959C (de) |
| DE (1) | DE69012572T2 (de) |
| DK (1) | DK0485525T3 (de) |
| ES (1) | ES2058935T3 (de) |
| HK (1) | HK1000520A1 (de) |
| WO (1) | WO1991002080A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5266477A (en) * | 1990-02-02 | 1993-11-30 | Pitman-Moore, Inc. | Monoclonal antibodies which differentiate between native and modified porcine somatotropins |
| US6884597B1 (en) * | 1998-01-20 | 2005-04-26 | Medical & Biological Laboratories, Co., Ltd. | Method for detecting acetyltransferase and deacetylase activities and method for screening inhibitors or enhancers of these enzymes |
| EP1050581A4 (de) * | 1998-01-20 | 2005-10-19 | Med & Biological Lab Co Ltd | Verfahren zur detektion von acetyltransferase- und deacetylaseaktivitäten und verfahren zum auffinden von hemmstoffen oder beschleunigern dieser enzyme |
| JP4583638B2 (ja) * | 2001-03-15 | 2010-11-17 | 独立行政法人科学技術振興機構 | アセチルリジン認識モノクローナル抗体及びその製造方法 |
-
1990
- 1990-07-16 EP EP90914290A patent/EP0485525B1/de not_active Expired - Lifetime
- 1990-07-16 JP JP2513358A patent/JPH05500007A/ja active Pending
- 1990-07-16 DE DE69012572T patent/DE69012572T2/de not_active Expired - Fee Related
- 1990-07-16 WO PCT/US1990/003879 patent/WO1991002080A2/en active IP Right Grant
- 1990-07-16 ES ES90914290T patent/ES2058935T3/es not_active Expired - Lifetime
- 1990-07-16 CA CA002062959A patent/CA2062959C/en not_active Expired - Fee Related
- 1990-07-16 DK DK90914290.3T patent/DK0485525T3/da active
- 1990-07-16 AU AU64229/90A patent/AU6422990A/en not_active Abandoned
- 1990-07-16 AT AT90914290T patent/ATE111531T1/de not_active IP Right Cessation
-
1992
- 1992-02-03 US US07/830,431 patent/US5849499A/en not_active Expired - Fee Related
-
1997
- 1997-11-06 HK HK97102117A patent/HK1000520A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2058935T3 (es) | 1994-11-01 |
| ATE111531T1 (de) | 1994-09-15 |
| US5849499A (en) | 1998-12-15 |
| WO1991002080A3 (en) | 1991-03-21 |
| DE69012572D1 (de) | 1994-10-20 |
| AU6422990A (en) | 1991-03-11 |
| WO1991002080A2 (en) | 1991-02-21 |
| DK0485525T3 (da) | 1995-02-20 |
| CA2062959A1 (en) | 1991-02-05 |
| CA2062959C (en) | 1999-06-29 |
| EP0485525B1 (de) | 1994-09-14 |
| HK1000520A1 (en) | 1998-04-03 |
| JPH05500007A (ja) | 1993-01-14 |
| EP0485525A1 (de) | 1992-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US |
|
| 8339 | Ceased/non-payment of the annual fee |