DE69011367D1 - Verfahren zur Herstellung von substituierten 2,3-Pyridindicarbonsäuren durch aufeinanderfolgende Oxidation von substituierten Chinolinen. - Google Patents

Verfahren zur Herstellung von substituierten 2,3-Pyridindicarbonsäuren durch aufeinanderfolgende Oxidation von substituierten Chinolinen.

Info

Publication number
DE69011367D1
DE69011367D1 DE69011367T DE69011367T DE69011367D1 DE 69011367 D1 DE69011367 D1 DE 69011367D1 DE 69011367 T DE69011367 T DE 69011367T DE 69011367 T DE69011367 T DE 69011367T DE 69011367 D1 DE69011367 D1 DE 69011367D1
Authority
DE
Germany
Prior art keywords
substituted
preparation
quinolines
sequential oxidation
pyridinedicarboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69011367T
Other languages
English (en)
Other versions
DE69011367T2 (de
Inventor
John Joseph Pascavage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DE69011367D1 publication Critical patent/DE69011367D1/de
Application granted granted Critical
Publication of DE69011367T2 publication Critical patent/DE69011367T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69011367T 1989-03-22 1990-02-09 Verfahren zur Herstellung von substituierten 2,3-Pyridindicarbonsäuren durch aufeinanderfolgende Oxidation von substituierten Chinolinen. Expired - Lifetime DE69011367T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32694089A 1989-03-22 1989-03-22

Publications (2)

Publication Number Publication Date
DE69011367D1 true DE69011367D1 (de) 1994-09-15
DE69011367T2 DE69011367T2 (de) 1995-03-23

Family

ID=23274431

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69011367T Expired - Lifetime DE69011367T2 (de) 1989-03-22 1990-02-09 Verfahren zur Herstellung von substituierten 2,3-Pyridindicarbonsäuren durch aufeinanderfolgende Oxidation von substituierten Chinolinen.

Country Status (12)

Country Link
EP (1) EP0388619B1 (de)
JP (1) JP2825596B2 (de)
KR (1) KR0141483B1 (de)
CN (1) CN1030569C (de)
AT (1) ATE109772T1 (de)
CA (1) CA2012558C (de)
DE (1) DE69011367T2 (de)
DK (1) DK0388619T3 (de)
ES (1) ES2058625T3 (de)
IE (1) IE66018B1 (de)
IL (1) IL93394A (de)
ZA (1) ZA902184B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206368A (en) * 1991-03-12 1993-04-27 American Cyanamid Company Process for extracting pyridine- and quinolinedicarboxylic acids from aqueous media
EP0661268B1 (de) * 1993-12-28 1998-04-22 American Cyanamid Company Verfahren zur Herstellung Pyridin-2,3-dicarboxylicsäure
US5686470A (en) * 1995-02-10 1997-11-11 Weier; Richard M. 2, 3-substituted pyridines for the treatment of inflammation
NZ314904A (en) * 1996-06-10 1998-06-26 American Cyanamid Co Preparation of a herbicidal [(5,6-dicarboxy-3-pyridyl)methyl]ammonium halide
NL1006596C2 (nl) * 1997-07-16 1999-01-19 Dsm Nv Werkwijze voor de bereiding van 5-methoxymethylpyridine-2, 3-dicarbonzuur en derivaten daarvan.
US6174901B1 (en) 1998-12-18 2001-01-16 Amgen Inc. Substituted pyridine and pyridazine compounds and methods of use
CN103193713A (zh) * 2013-04-09 2013-07-10 常州博海威医药科技有限公司 一种制备2-丙级咪唑-4,5-二羧酸的方法
CN105646120B (zh) * 2014-12-02 2019-03-19 浙江省诸暨合力化学对外贸易有限公司 一种羧酸的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623726A (en) * 1983-04-18 1986-11-18 American Cyanamid Company Method for oxidizing alkyl groups on pyridine, quinoline and benzene ring compounds to carboxylic acids under basic conditions
US4736036A (en) * 1983-08-08 1988-04-05 Appleton Papers Inc. Process for the preparation of quinolinic acid
DE3345223A1 (de) * 1983-12-14 1985-06-27 Rütgerswerke AG, 6000 Frankfurt Verfahren zur herstellung von chinolinsaeure aus chinolin
US4754039A (en) * 1986-01-30 1988-06-28 Ruetgers-Nease Chemical Co., Inc. Process for the preparation of pyridine-2,3-dicarboxylic acid
DE3771153D1 (de) * 1986-09-12 1991-08-08 American Cyanamid Co Verfahren zur herstellung von pyridin-2,3-dicarboxylsaeuren.
IL89142A (en) * 1988-03-10 1993-04-04 American Cyanamid Co Method for the sequential oxidation of substituted 8-hydroxyquinolines to produce substituted pyridine-2,3- dicarboxylic acids

Also Published As

Publication number Publication date
IE901030L (en) 1990-09-22
KR0141483B1 (ko) 1998-06-01
CN1045776A (zh) 1990-10-03
KR900014320A (ko) 1990-10-23
JPH02286660A (ja) 1990-11-26
IL93394A (en) 1994-08-26
ATE109772T1 (de) 1994-08-15
DK0388619T3 (da) 1994-10-03
ZA902184B (en) 1991-11-27
EP0388619A1 (de) 1990-09-26
IE66018B1 (en) 1995-11-29
CN1030569C (zh) 1995-12-27
EP0388619B1 (de) 1994-08-10
DE69011367T2 (de) 1995-03-23
CA2012558A1 (en) 1990-09-22
JP2825596B2 (ja) 1998-11-18
IL93394A0 (en) 1990-11-29
CA2012558C (en) 2001-04-03
ES2058625T3 (es) 1994-11-01

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