DE69008727D1 - Orale osmotische vorrichtung mit einem hydrogel als treibendes teil. - Google Patents
Orale osmotische vorrichtung mit einem hydrogel als treibendes teil.Info
- Publication number
- DE69008727D1 DE69008727D1 DE69008727T DE69008727T DE69008727D1 DE 69008727 D1 DE69008727 D1 DE 69008727D1 DE 69008727 T DE69008727 T DE 69008727T DE 69008727 T DE69008727 T DE 69008727T DE 69008727 D1 DE69008727 D1 DE 69008727D1
- Authority
- DE
- Germany
- Prior art keywords
- wall
- agent
- delivered
- drug
- hydrophilic polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Dental Preparations (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Plant Substances (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- External Artificial Organs (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/380,229 US5021053A (en) | 1989-07-14 | 1989-07-14 | Oral osmotic device with hydrogel driving member |
PCT/US1990/003882 WO1991001130A1 (en) | 1989-07-14 | 1990-07-11 | Oral osmotic device with hydrogel driving member |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69008727D1 true DE69008727D1 (de) | 1994-06-09 |
DE69008727T2 DE69008727T2 (de) | 1994-08-18 |
Family
ID=23500397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69008727T Expired - Fee Related DE69008727T2 (de) | 1989-07-14 | 1990-07-11 | Orale osmotische vorrichtung mit einem hydrogel als treibendes teil. |
Country Status (18)
Country | Link |
---|---|
US (2) | US5021053A (de) |
EP (1) | EP0482075B1 (de) |
JP (1) | JPH05502215A (de) |
KR (1) | KR920703020A (de) |
AT (1) | ATE105182T1 (de) |
AU (1) | AU633340B2 (de) |
CA (1) | CA2020955C (de) |
DE (1) | DE69008727T2 (de) |
DK (1) | DK0482075T3 (de) |
ES (1) | ES2052263T3 (de) |
FI (1) | FI920164A0 (de) |
GR (1) | GR1000650B (de) |
IE (1) | IE62717B1 (de) |
NO (1) | NO915043L (de) |
NZ (2) | NZ234447A (de) |
PT (1) | PT94664B (de) |
WO (1) | WO1991001130A1 (de) |
ZA (1) | ZA905429B (de) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776493A (en) * | 1989-07-14 | 1998-07-07 | Alza Corporation | Oral osmotic device for delivery of nystatin with hydrogel driving member |
ATE111351T1 (de) * | 1990-07-23 | 1994-09-15 | Alza Corp | Oral anzuwendende osmotische vorrichtung zur abgabe von nicotin. |
US5147654A (en) * | 1990-07-23 | 1992-09-15 | Alza Corporation | Oral osmotic device for delivering nicotine |
US5575995A (en) * | 1991-08-15 | 1996-11-19 | Giovanoni; Richard L. | Ferric subsulfate gel and methods of using same |
US5340581A (en) * | 1991-08-23 | 1994-08-23 | Gillette Canada, Inc. | Sustained-release matrices for dental application |
US5200195A (en) * | 1991-12-06 | 1993-04-06 | Alza Corporation | Process for improving dosage form delivery kinetics |
US5254349A (en) * | 1991-12-06 | 1993-10-19 | Alza Corporation | Process for lessening irritation caused by drug |
US5266332A (en) * | 1991-12-06 | 1993-11-30 | Alza Corporation | Method for administering anti-Parkinson drug |
US5200194A (en) * | 1991-12-18 | 1993-04-06 | Alza Corporation | Oral osmotic device |
US5294770A (en) * | 1992-01-14 | 1994-03-15 | Alza Corporation | Laser tablet treatment system with dual access to tablet |
US5248310A (en) * | 1992-03-27 | 1993-09-28 | Alza Corporation | Oral osmotic device with hydrogel driving member |
US5512299A (en) * | 1992-03-30 | 1996-04-30 | Alza Corporation | Method of treating oral inflammatory disease |
US5294433A (en) * | 1992-04-15 | 1994-03-15 | The Procter & Gamble Company | Use of H-2 antagonists for treatment of gingivitis |
US5661171A (en) * | 1992-07-02 | 1997-08-26 | Oramed, Inc. | Controlled release pilocarpine delivery system |
WO1994001108A1 (en) * | 1992-07-02 | 1994-01-20 | Theratech, Inc. | Controlled release pilocarpine delivery system |
US5512293A (en) * | 1992-07-23 | 1996-04-30 | Alza Corporation | Oral sustained release drug delivery device |
US5573776A (en) * | 1992-12-02 | 1996-11-12 | Alza Corporation | Oral osmotic device with hydrogel driving member |
US5368588A (en) * | 1993-02-26 | 1994-11-29 | Bettinger; David S. | Parenteral fluid medication reservoir pump |
DE4313928C2 (de) * | 1993-04-28 | 1996-09-19 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur kontrollierten Abgabe von Pilocarpin an die Haut, Verfahren zu seiner Herstellung und seine Verwendung |
US5460826A (en) * | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
US5529787A (en) * | 1994-07-07 | 1996-06-25 | Alza Corporation | Hydromorphone therapy |
US5914131A (en) * | 1994-07-07 | 1999-06-22 | Alza Corporation | Hydromorphone therapy |
US5681568A (en) * | 1994-08-19 | 1997-10-28 | Cambridge Neuroscience, Inc. | Device for delivery of substances and methods of use thereof |
US6491945B1 (en) * | 1994-09-16 | 2002-12-10 | Alza Corporation | Hydrocodone therapy |
US5827180A (en) * | 1994-11-07 | 1998-10-27 | Lifemasters Supported Selfcare | Method and apparatus for a personal health network |
US5658474A (en) * | 1994-12-16 | 1997-08-19 | Alza Corporation | Method and apparatus for forming dispenser delivery ports |
US5656284A (en) * | 1995-04-24 | 1997-08-12 | Balkin; Michael S. | Oral transmucosal delivery tablet and method of making it |
US5713852A (en) * | 1995-06-07 | 1998-02-03 | Alza Corporation | Oral dosage and method for treating painful conditions of the oral cavity |
FR2737661B1 (fr) * | 1995-08-08 | 1997-10-31 | Mgi Pharma Inc | Composition pharmaceutique sous forme de comprimes comprenant du chlorhydrate de pilocarpine |
EP0914097B1 (de) * | 1996-03-12 | 2002-01-16 | Alza Corporation | Zusammensetzung und dosisform mit einem opioid-antagonisten |
US5948787A (en) * | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
US6284262B1 (en) * | 1999-01-26 | 2001-09-04 | Virgil A. Place | Compact dosage unit for buccal administration of a pharmacologically active agent |
US6319510B1 (en) | 1999-04-20 | 2001-11-20 | Alayne Yates | Gum pad for delivery of medication to mucosal tissues |
US6562375B1 (en) | 1999-08-04 | 2003-05-13 | Yamanouchi Pharmaceuticals, Co., Ltd. | Stable pharmaceutical composition for oral use |
US6491683B1 (en) * | 1999-09-07 | 2002-12-10 | Alza Corporation | Osmotic dosage form composed of an extruded polymer tube form |
US6242003B1 (en) | 2000-04-13 | 2001-06-05 | Novartis Ag | Organic compounds |
US20060127474A1 (en) * | 2001-04-11 | 2006-06-15 | Oskar Kalb | Pharmaceutical compositions comprising fluvastatin |
US20030035839A1 (en) * | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
US6863901B2 (en) * | 2001-11-30 | 2005-03-08 | Collegium Pharmaceutical, Inc. | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration |
US6827946B2 (en) * | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
US7328706B2 (en) | 2002-05-06 | 2008-02-12 | Dynamic Mouth Devices Llc | Therapeutic and protective dental device useful as an intra-oral delivery system |
EP1539270A1 (de) * | 2002-09-18 | 2005-06-15 | Medtronic Vascular, Inc. | Steuerbare, arznemittelfreisetzende gradientbeschichtungen für medizinische vorrichtungen |
CA2499550C (en) | 2002-09-20 | 2013-10-15 | Alpharma, Inc. | Sequestering subunit and related compositions and methods |
US7306812B2 (en) * | 2003-05-09 | 2007-12-11 | Cephalon, Inc. | Dissolvable backing layer for use with a transmucosal delivery device |
US7276246B2 (en) * | 2003-05-09 | 2007-10-02 | Cephalon, Inc. | Dissolvable backing layer for use with a transmucosal delivery device |
ATE504288T1 (de) * | 2003-09-26 | 2011-04-15 | Alza Corp | Oros-push-stick für die kontrollierte abgabe von wirkstoffen |
AU2004275835B2 (en) * | 2003-09-26 | 2011-06-23 | Alza Corporation | Controlled release formulations exhibiting an ascending rate of release |
US8246986B2 (en) * | 2003-09-26 | 2012-08-21 | Alza Corporation | Drug coating providing high drug loading |
WO2005030181A1 (en) * | 2003-09-26 | 2005-04-07 | Alza Corporation | Controlled release formulations of opioid and nonopioid analgesics |
US8541026B2 (en) * | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
US20070048347A1 (en) | 2005-08-26 | 2007-03-01 | Laura Bardach | Intra-oral device for treating obesity |
HUE032156T2 (en) | 2006-06-19 | 2017-09-28 | Alpharma Pharmaceuticals Llc | Pharmaceutical preparations |
WO2008105920A1 (en) * | 2007-02-28 | 2008-09-04 | Collegium Pharmaceutical, Inc. | Antihistamine combination |
US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
CN102573811A (zh) | 2009-06-02 | 2012-07-11 | 陶氏环球技术有限责任公司 | 缓释剂型 |
US10575976B2 (en) | 2015-04-30 | 2020-03-03 | Dynamic Mouth Devices, L.L.C. | Method and apparatus for weight management utilizing an intra-oral device |
JP6982870B2 (ja) | 2015-05-06 | 2021-12-17 | シンアジャル コーポレイション | 薬物粒子を含有する医薬懸濁液、それらの投与のためのデバイス、およびそれらの使用方法 |
CN106344535B (zh) * | 2016-08-29 | 2019-09-20 | 济南康和医药科技有限公司 | 一种氟伐他汀钠微孔渗透泵控释片及其制备方法 |
US10758329B1 (en) | 2019-08-20 | 2020-09-01 | Raymond L. Wright, III | Hydrating mouth guard |
US11529310B2 (en) | 2020-12-08 | 2022-12-20 | Ruminant Biotech Corp Limited | Devices and methods for delivery of substances to animals |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3402240A (en) * | 1957-06-25 | 1968-09-17 | Pfizer & Co C | Medicinal tablet and process of making same |
US3054724A (en) * | 1960-05-12 | 1962-09-18 | Smith Kline French Lab | Coloring discrete solids and compositions therefor |
US3732865A (en) * | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
US4238475A (en) * | 1979-08-01 | 1980-12-09 | Life Savers Inc. | Chewing cum capable of releasing finely divided water-insoluble materials therefrom |
US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
GB2122892B (en) * | 1982-07-02 | 1986-01-29 | Squibb & Sons Inc | Nystantin pastille formulation |
CA1208558A (en) * | 1982-10-07 | 1986-07-29 | Kazuo Kigasawa | Soft buccal |
US4783337A (en) * | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
US4749575A (en) * | 1983-10-03 | 1988-06-07 | Bio-Dar Ltd. | Microencapsulated medicament in sweet matrix |
US4639368A (en) * | 1984-08-23 | 1987-01-27 | Farmacon Research Corporation | Chewing gum containing a medicament and taste maskers |
US4627971A (en) * | 1985-04-22 | 1986-12-09 | Alza Corporation | Osmotic device with self-sealing passageway |
US4666705A (en) * | 1985-06-03 | 1987-05-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US4713243A (en) * | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
JPS63188621A (ja) * | 1987-01-30 | 1988-08-04 | Taisho Pharmaceut Co Ltd | 矯味経口製剤 |
US4983394A (en) * | 1990-05-03 | 1991-01-08 | Warner-Lambert Company | Flavor enhancing and medicinal taste masking agent |
-
1989
- 1989-07-14 US US07/380,229 patent/US5021053A/en not_active Expired - Lifetime
-
1990
- 1990-07-11 PT PT94664A patent/PT94664B/pt not_active IP Right Cessation
- 1990-07-11 NZ NZ234447A patent/NZ234447A/en unknown
- 1990-07-11 DE DE69008727T patent/DE69008727T2/de not_active Expired - Fee Related
- 1990-07-11 WO PCT/US1990/003882 patent/WO1991001130A1/en active IP Right Grant
- 1990-07-11 AU AU60476/90A patent/AU633340B2/en not_active Ceased
- 1990-07-11 NZ NZ243890A patent/NZ243890A/en unknown
- 1990-07-11 ZA ZA905429A patent/ZA905429B/xx unknown
- 1990-07-11 ES ES90911340T patent/ES2052263T3/es not_active Expired - Lifetime
- 1990-07-11 IE IE252590A patent/IE62717B1/en not_active IP Right Cessation
- 1990-07-11 AT AT9090911340T patent/ATE105182T1/de not_active IP Right Cessation
- 1990-07-11 EP EP90911340A patent/EP0482075B1/de not_active Expired - Lifetime
- 1990-07-11 CA CA002020955A patent/CA2020955C/en not_active Expired - Lifetime
- 1990-07-11 DK DK90911340.9T patent/DK0482075T3/da active
- 1990-07-11 JP JP2510587A patent/JPH05502215A/ja active Pending
- 1990-07-11 GR GR900100531A patent/GR1000650B/el unknown
- 1990-07-11 KR KR1019920700069A patent/KR920703020A/ko not_active Application Discontinuation
- 1990-12-21 US US07/633,590 patent/US5053032A/en not_active Expired - Lifetime
-
1991
- 1991-12-20 NO NO91915043A patent/NO915043L/no unknown
-
1992
- 1992-01-14 FI FI920164A patent/FI920164A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ243890A (en) | 1993-03-26 |
ES2052263T3 (es) | 1994-07-01 |
GR1000650B (el) | 1992-09-11 |
KR920703020A (ko) | 1992-12-17 |
ATE105182T1 (de) | 1994-05-15 |
EP0482075A1 (de) | 1992-04-29 |
PT94664B (pt) | 1997-09-30 |
US5053032A (en) | 1991-10-01 |
PT94664A (pt) | 1991-04-18 |
NO915043L (no) | 1992-01-13 |
AU6047690A (en) | 1991-02-22 |
CA2020955A1 (en) | 1991-01-15 |
DE69008727T2 (de) | 1994-08-18 |
IE902525A1 (en) | 1991-02-13 |
EP0482075B1 (de) | 1994-05-04 |
CA2020955C (en) | 2000-10-31 |
FI920164A0 (fi) | 1992-01-14 |
DK0482075T3 (da) | 1994-08-15 |
AU633340B2 (en) | 1993-01-28 |
ZA905429B (en) | 1991-04-24 |
NO915043D0 (no) | 1991-12-20 |
NZ234447A (en) | 1993-03-26 |
JPH05502215A (ja) | 1993-04-22 |
IE62717B1 (en) | 1995-02-22 |
GR900100531A (en) | 1991-12-10 |
WO1991001130A1 (en) | 1991-02-07 |
US5021053A (en) | 1991-06-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |