DE69006274D1 - Heterozyklische sulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen. - Google Patents

Heterozyklische sulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen.

Info

Publication number
DE69006274D1
DE69006274D1 DE90902343T DE69006274T DE69006274D1 DE 69006274 D1 DE69006274 D1 DE 69006274D1 DE 90902343 T DE90902343 T DE 90902343T DE 69006274 T DE69006274 T DE 69006274T DE 69006274 D1 DE69006274 D1 DE 69006274D1
Authority
DE
Germany
Prior art keywords
ring
phenyl
alkyl
atoms
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE90902343T
Other languages
English (en)
Inventor
Keith Blakeney Mallion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of DE69006274D1 publication Critical patent/DE69006274D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE90902343T 1989-02-03 1990-02-01 Heterozyklische sulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen. Expired - Lifetime DE69006274D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898902405A GB8902405D0 (en) 1989-02-03 1989-02-03 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
DE69006274D1 true DE69006274D1 (de) 1994-03-10

Family

ID=10651067

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90902343T Expired - Lifetime DE69006274D1 (de) 1989-02-03 1990-02-01 Heterozyklische sulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen.

Country Status (15)

Country Link
US (1) US5096918A (de)
EP (1) EP0408714B1 (de)
JP (1) JPH03503900A (de)
AT (1) ATE100797T1 (de)
AU (1) AU631400B2 (de)
CA (1) CA2025664A1 (de)
DE (1) DE69006274D1 (de)
GB (1) GB8902405D0 (de)
GR (1) GR1000444B (de)
IE (1) IE900255L (de)
IL (1) IL93177A0 (de)
NZ (1) NZ232348A (de)
PT (1) PT93051A (de)
WO (1) WO1990008762A1 (de)
ZA (1) ZA90637B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
KR950703539A (ko) * 1992-09-28 1995-09-20 알렌 제이. 스피겔 당뇨병 합병증 치료용 치환된 피리미딘(substituted pyrimidines for control or diabetic complications)
US5516534A (en) * 1993-11-26 1996-05-14 Rensselaer Polytechnic Institute Composition and method for reducing structural defects

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1229653A (de) * 1968-03-14 1971-04-28
US4053633A (en) * 1976-06-24 1977-10-11 The Dow Chemical Company Aryl dibromonitromethyl sulfones
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions

Also Published As

Publication number Publication date
IE900255L (en) 1990-08-03
ATE100797T1 (de) 1994-02-15
PT93051A (pt) 1990-08-31
CA2025664A1 (en) 1990-08-04
NZ232348A (en) 1992-04-28
US5096918A (en) 1992-03-17
WO1990008762A1 (en) 1990-08-09
GB8902405D0 (en) 1989-03-22
JPH03503900A (ja) 1991-08-29
AU631400B2 (en) 1992-11-26
GR1000444B (el) 1992-07-30
AU5020890A (en) 1990-08-24
EP0408714B1 (de) 1994-01-26
IL93177A0 (en) 1990-11-05
GR900100067A (en) 1991-06-28
EP0408714A1 (de) 1991-01-23
ZA90637B (en) 1990-10-31

Similar Documents

Publication Publication Date Title
ATE9793T1 (de) 5-oxo- und 5-thioxoproline, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
AU5670690A (en) Lysolecithin derivatives for treating autoimmune diseases
DE69006274D1 (de) Heterozyklische sulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen.
KR920018036A (ko) 티아졸리디논 및 옥사졸리디논 유도체, 그의 제조방법 및 혈관확장제로서의 용도
DE69324066T2 (de) 4-Phenylcarbamoyl-3-isoxazolecarbonsäure-Derivate mit entzündungshemmender Aktivität
ATE48276T1 (de) 1,6-naphthyridin-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel.
DE3787844D1 (de) Thioester und dessen Verwendung zur Herstellung von pharmazeutischen Zusammensetzungen zur Behandlung von Ischämie und von Reperfusion-Syndromen.
DE3676378D1 (de) Isoxazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutischen praeparate.
SE7904543L (sv) Nya joniska bensen-polyjodidderivat for anvendning som kontrastmedel vid rontgenbehandling
DE69008956D1 (de) Arylsulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen.
ATE15667T1 (de) Neue substituierte 3,5-diamino-1,2,4-oxadiazole und 3,5-diamino-1,2,4-thiadiazole, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DE3678645D1 (de) Neue thieno-1,2-thiazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
DE3770117D1 (de) Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3-phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ATE2527T1 (de) Thienylbenzoesaeurederivate, verfahren zu ihrer herstellung und pharmazeutische praeparate auf basis dieser verbindungen.
ATE19879T1 (de) Furyloxazolylessigsaeure-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
JPS56133292A (en) Novel derivatives of cycloheptoindole, salts with their acids, their manufacture, application as drug and composition containing them
ATE4541T1 (de) Alkyl- und cycloalkylsubstituierte 2-(2-(2hydroxy-3-tert.-butylamino-propoxy)-5-acylamino phenyl)-1,3,4-oxadiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen.
ZA857945B (en) 4-hydroxy-3-quinoline carboxylic acid derivatives substituted at position 2 by an alpha-hydroxylated chain,process for their preparation,their use as medicaments and compositions containing them
ATE33493T1 (de) Phenylethylaminopropiophenon-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ATE139780T1 (de) Amidderivate von 1-amino-octahydropyrido(2,1- c>(1,4>oxazin, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
GB2022583A (en) New ionic polyiodo benzene derivatives useful as X-ray contrast media

Legal Events

Date Code Title Description
8332 No legal effect for de