DE69005908D1 - Monoklonale Antikörper zur Behandlung nach einem Kontakt mit Tollwutvirus. - Google Patents

Monoklonale Antikörper zur Behandlung nach einem Kontakt mit Tollwutvirus.

Info

Publication number
DE69005908D1
DE69005908D1 DE90305844T DE69005908T DE69005908D1 DE 69005908 D1 DE69005908 D1 DE 69005908D1 DE 90305844 T DE90305844 T DE 90305844T DE 69005908 T DE69005908 T DE 69005908T DE 69005908 D1 DE69005908 D1 DE 69005908D1
Authority
DE
Germany
Prior art keywords
rabies
treatment
virus
contact
monoclonal antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90305844T
Other languages
English (en)
Other versions
DE69005908T2 (de
Inventor
Bernhard Dietzschold
Charles E Rupprecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wistar Institute of Anatomy and Biology
Original Assignee
Wistar Institute of Anatomy and Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wistar Institute of Anatomy and Biology filed Critical Wistar Institute of Anatomy and Biology
Publication of DE69005908D1 publication Critical patent/DE69005908D1/de
Application granted granted Critical
Publication of DE69005908T2 publication Critical patent/DE69005908T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE90305844T 1989-06-08 1990-05-30 Monoklonale Antikörper zur Behandlung nach einem Kontakt mit Tollwutvirus. Expired - Fee Related DE69005908T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36514389A 1989-06-08 1989-06-08

Publications (2)

Publication Number Publication Date
DE69005908D1 true DE69005908D1 (de) 1994-02-24
DE69005908T2 DE69005908T2 (de) 1994-04-28

Family

ID=23437645

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90305844T Expired - Fee Related DE69005908T2 (de) 1989-06-08 1990-05-30 Monoklonale Antikörper zur Behandlung nach einem Kontakt mit Tollwutvirus.

Country Status (6)

Country Link
EP (1) EP0402029B1 (de)
AT (1) ATE99958T1 (de)
AU (1) AU626684B2 (de)
CA (1) CA2018508A1 (de)
DE (1) DE69005908T2 (de)
ES (1) ES2062364T3 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4006630A1 (de) * 1990-03-03 1991-09-12 Behringwerke Ag Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
SI1523496T1 (sl) 2002-07-18 2011-11-30 Merus B V Rekombinantno proizvajanje zmesi protiteles
WO2004106375A1 (en) 2003-05-30 2004-12-09 Merus Biopharmaceuticals B.V. I.O. Fab library for the preparation of anti vegf and anti rabies virus fabs
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
DK1737971T3 (da) 2004-01-20 2017-11-13 Merus Nv Blandinger af bindingsproteiner
EP2314620B1 (de) * 2004-05-27 2013-06-05 Crucell Holland B.V. Verfahren zur Identifikation von Bindungsmoleküle, die zur Neutralisierung des Tollwutvirus fähig sind
AU2011218689C1 (en) * 2004-05-27 2013-05-30 Crucell Holland B.V. Binding molecules capable of neutralizing rabies virus and uses thereof
CN103351435B (zh) 2006-06-06 2015-08-19 克鲁塞尔荷兰公司 具有杀灭葡萄球菌活性的人结合分子及其应用
US7959922B2 (en) 2006-12-05 2011-06-14 Crucell Holland B.V. Liquid anti-rabies antibody formulations
WO2011028961A2 (en) 2009-09-04 2011-03-10 Xoma Technology Ltd. Anti-botulism antibody coformulations
WO2012054502A1 (en) * 2010-10-19 2012-04-26 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Identification of antibodies specific for lyssaviruses and methods of their use
EA035344B1 (ru) 2012-04-20 2020-05-29 Мерюс Н.В. Способ получения двух антител из одной клетки-хозяина
CN108135999B (zh) * 2015-08-13 2022-05-31 马萨诸塞大学 针对狂犬病的人抗体及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652629A (en) * 1985-07-03 1987-03-24 The Salk Institute For Biological Studies Synthetic peptide-based anti-rabies compositions and methods

Also Published As

Publication number Publication date
CA2018508A1 (en) 1990-12-08
EP0402029A3 (de) 1991-02-13
ATE99958T1 (de) 1994-01-15
EP0402029B1 (de) 1994-01-12
AU5686890A (en) 1990-12-13
AU626684B2 (en) 1992-08-06
ES2062364T3 (es) 1994-12-16
EP0402029A2 (de) 1990-12-12
DE69005908T2 (de) 1994-04-28

Similar Documents

Publication Publication Date Title
DE69005908D1 (de) Monoklonale Antikörper zur Behandlung nach einem Kontakt mit Tollwutvirus.
NO942530L (no) Chimeriske Immunogener
ATE101648T1 (de) Expression eines tumorspezifischen antigens eines rekombinanten virusvektors sowie dessen anwendung zur versorgenden oder heilenden behandlung des entsprechenden tumors.
ATE45961T1 (de) Humanes cytomegalovirus immunserumglobulin mit hohem titer und verfahren zu seiner herstellung.
DE69030383D1 (de) Impfstoff-Konjugate zur Behandlung von Vogelkrankheiten
ATE175123T1 (de) Verbesserte immunotherapeutische methode zur verhinderung oder behandlung viraler krankheiten der atemwege
DE68908431D1 (de) Methode zur verminderung der immunglobulin-e-reaktion.
DE3584872D1 (de) Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag.
ES2165884T3 (es) Preparacion farmaceutica estable que no contiene actividad viral consistente en al menos un 70%, preferiblemente un 90% de inmunoglobulina a humana monomera, y procedimiento de preparacion.
Pedersen Jr et al. Separation, isolation, and immunological studies of the structural proteins of Venezuelan equine encephalomyelitis virus
ATE148348T1 (de) Behandlung von einer autoimmun-krankheit
ATE96675T1 (de) Spezifische sekretions-exkretions-antigene von toxoplasma gondii, deren expressionsprodukte, verfahren zu deren herstellung und deren diagnostische und prophylaktische anwendungen.
ATE122100T1 (de) Humaner monoklonaler antikörper und diesen enthaltende arzneimittelzusammensetzung zur behandlung von pseudomonasinfektionen.
Yoneda et al. Protection of mice from rabies by intranasal immunization with inactivated rabies virus
DK0542895T3 (da) Krydsreaktiv influenza A immunisering
ATE39055T1 (de) Verfahren zur immunisierung von schweinen gegen die aujeszky-krankheit.
NO923749L (no) Bcrf1-antagonister for behandling av epstein-barr-virusinfeksjoner
DE68913932D1 (de) Arzneimittel für die Behandlung oder die Verhütung von Infektionen mit HIV durch Immunisierung, und Verfahren zur Herstellung.
Kitamura et al. Immunological Studies of Heat‐Labile Virus Inhibitors: I. Specificity of Absorption onto Sensitive Viruses and Specific Response after Virus Infections
Randall et al. Immunization with external and/or internal structural proteins protects mice from infection with the paramyxovirus SV5
Lafon et al. Production of human monoclonal antibodies neutralizing rabies virus: An alternative to rabies immune globulin of human blood donation

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee