DE69000438D1 - Heterocyclische derivate. - Google Patents

Heterocyclische derivate.

Info

Publication number
DE69000438D1
DE69000438D1 DE9090300780T DE69000438T DE69000438D1 DE 69000438 D1 DE69000438 D1 DE 69000438D1 DE 9090300780 T DE9090300780 T DE 9090300780T DE 69000438 T DE69000438 T DE 69000438T DE 69000438 D1 DE69000438 D1 DE 69000438D1
Authority
DE
Germany
Prior art keywords
alkyl
optionally substituted
thiazole
substituted
alkynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090300780T
Other languages
English (en)
Other versions
DE69000438T2 (de
Inventor
Graham Charles Crawley
Martin Paul Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca SAS
Imperial Chemical Industries Ltd
Original Assignee
ICI Pharma SA
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICI Pharma SA, Imperial Chemical Industries Ltd filed Critical ICI Pharma SA
Publication of DE69000438D1 publication Critical patent/DE69000438D1/de
Application granted granted Critical
Publication of DE69000438T2 publication Critical patent/DE69000438T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE9090300780T 1989-01-30 1990-01-25 Heterocyclische derivate. Expired - Fee Related DE69000438T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89400251 1989-01-30

Publications (2)

Publication Number Publication Date
DE69000438D1 true DE69000438D1 (de) 1992-12-17
DE69000438T2 DE69000438T2 (de) 1993-03-25

Family

ID=8202915

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9090300780T Expired - Fee Related DE69000438T2 (de) 1989-01-30 1990-01-25 Heterocyclische derivate.

Country Status (13)

Country Link
US (2) US5089495A (de)
EP (1) EP0381375B1 (de)
JP (1) JPH03197471A (de)
AT (1) ATE82286T1 (de)
AU (1) AU626977B2 (de)
CA (1) CA2007654A1 (de)
DE (1) DE69000438T2 (de)
DK (1) DK0381375T3 (de)
ES (1) ES2053095T3 (de)
GR (1) GR3006324T3 (de)
IE (1) IE62558B1 (de)
NZ (1) NZ232094A (de)
ZA (1) ZA90264B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196422A (en) * 1988-07-12 1993-03-23 Ici Pharma 5-lipoxygenase inhibiting thiazoles
US5254581A (en) * 1990-06-21 1993-10-19 Imperial Chemical Industries Plc Pyran derivatives and their use as inhibitors of 5-lipoxygenase
IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
DE4139751A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
GB9122590D0 (en) * 1991-10-24 1991-12-04 Lilly Industries Ltd Pharmaceutical compounds
WO1993016081A1 (en) * 1992-02-13 1993-08-19 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
EP0632027A1 (de) * 1993-07-01 1995-01-04 BASF Aktiengesellschaft 6-(Carbonyloxymethylene)-Chinoline
DE4411657A1 (de) * 1994-04-02 1995-10-05 Basf Ag Verfahren zur Herstellung von 6-Hydroxymethylchinolinen
US5527827A (en) * 1994-10-27 1996-06-18 Merck Frosst Canada, Inc. Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis
US5552437A (en) * 1994-10-27 1996-09-03 Merck Frosst Canada, Inc. Bisarylcarbinol derivatives as inhibitors of leukotriene biosynthesis
US20040102325A1 (en) * 2000-10-03 2004-05-27 Schaetzer Juergen Phenylpropynyloxypyridine herbicides
US6548670B1 (en) 2001-07-19 2003-04-15 Air Products And Chemicals, Inc. Methods for preparing 5- and 6-benzyl-functionalized quinoxalines
US6825221B2 (en) 2001-10-18 2004-11-30 Allergan, Inc. Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
US4721721A (en) * 1984-12-18 1988-01-26 Rorer Pharmaceutical Corporation 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4876346A (en) * 1985-05-02 1989-10-24 American Home Products Corporation Quinoline compounds
US4661499A (en) * 1985-06-18 1987-04-28 Merck Frosst Canada, Inc. 2-[(substituted)-phenoxymethyl]quinolines
JPS62142168A (ja) * 1985-10-16 1987-06-25 Mitsubishi Chem Ind Ltd チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤
AU612569B2 (en) * 1986-03-13 1991-07-18 Rorer International (Overseas) Inc. Quinolinyl ether or thioether tetrazoles as agents for the treatment of hypersensitive ailments
GB8820389D0 (en) * 1988-08-26 1988-09-28 Beecham Group Plc Novel compounds
IL93344A0 (en) * 1989-02-28 1990-11-29 Ici Plc Heterocyclic cyclic ethers
IL93343A0 (en) * 1989-02-28 1990-11-29 Ici Plc Heterocyclic cycloalkanes

Also Published As

Publication number Publication date
EP0381375A1 (de) 1990-08-08
AU626977B2 (en) 1992-08-13
EP0381375B1 (de) 1992-11-11
ATE82286T1 (de) 1992-11-15
DE69000438T2 (de) 1993-03-25
IE62558B1 (en) 1995-02-08
IE900144L (en) 1990-07-30
JPH03197471A (ja) 1991-08-28
DK0381375T3 (da) 1993-01-25
US5089495A (en) 1992-02-18
ES2053095T3 (es) 1994-07-16
NZ232094A (en) 1992-06-25
US5283245A (en) 1994-02-01
AU4859690A (en) 1990-08-02
ZA90264B (en) 1990-10-31
CA2007654A1 (en) 1990-07-30
GR3006324T3 (de) 1993-06-21

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FI901010A0 (fi) Heterocykliska cykliska etrar.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee