DE68928925D1 - Antimikrobielle Fluorochinolonylcephemderivate - Google Patents
Antimikrobielle FluorochinolonylcephemderivateInfo
- Publication number
- DE68928925D1 DE68928925D1 DE68928925T DE68928925T DE68928925D1 DE 68928925 D1 DE68928925 D1 DE 68928925D1 DE 68928925 T DE68928925 T DE 68928925T DE 68928925 T DE68928925 T DE 68928925T DE 68928925 D1 DE68928925 D1 DE 68928925D1
- Authority
- DE
- Germany
- Prior art keywords
- antimicrobial
- fluoroquinolonylcephem
- derivatives
- halogen
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26194988A | 1988-10-24 | 1988-10-24 | |
US41802589A | 1989-10-12 | 1989-10-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68928925D1 true DE68928925D1 (de) | 1999-03-18 |
DE68928925T2 DE68928925T2 (de) | 1999-08-26 |
Family
ID=26948930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68928925T Expired - Fee Related DE68928925T2 (de) | 1988-10-24 | 1989-10-20 | Antimikrobielle Fluorochinolonylcephemderivate |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0366640B1 (de) |
JP (1) | JPH03503421A (de) |
KR (1) | KR0139638B1 (de) |
AT (1) | ATE176473T1 (de) |
AU (1) | AU620651B2 (de) |
CA (1) | CA2001204A1 (de) |
DE (1) | DE68928925T2 (de) |
DK (1) | DK527389A (de) |
ES (1) | ES2129388T3 (de) |
GR (1) | GR3030052T3 (de) |
NZ (1) | NZ231113A (de) |
PH (1) | PH26519A (de) |
SG (1) | SG54293A1 (de) |
WO (1) | WO1990004595A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5147871A (en) * | 1986-07-03 | 1992-09-15 | Hoffmann La-Roche, Inc. | Anti-bacterial cephalosporin compounds |
US5336768A (en) * | 1988-05-24 | 1994-08-09 | Hoffmann-La Roche Inc. | Antibacterial cephalosporin compounds |
CS273349B2 (en) * | 1988-03-31 | 1991-03-12 | Hoffmann La Roche | Method of cephalosporin's new derivatives production |
US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
EP0366189A3 (de) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Antimikrobielle Lactam-Quinolone |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
US5162523A (en) * | 1989-07-21 | 1992-11-10 | Hoffmann-La Roche Inc. | Cephalosporin antibacterial compounds |
US5159077A (en) * | 1989-07-21 | 1992-10-27 | Hoffmann-La Roche Inc. | Penam antibacterial compounds |
EP0525057B1 (de) * | 1990-04-18 | 2000-06-14 | Procter & Gamble Pharmaceuticals, Inc. | Antimikrobielle chinolonyl-lactame |
US5066800A (en) * | 1990-04-27 | 1991-11-19 | Hoffmann-La Roche Inc. | Qunoline intermediates useful therein for synthesizing antibacterial compounds |
DE69218445T2 (de) * | 1991-10-01 | 1997-08-07 | Procter & Gamble Pharma | Verfahren zur herstellung von antimikrobiellen quinolonyl-lactamen |
DE4234330A1 (de) * | 1992-10-12 | 1994-04-14 | Bayer Ag | Chinoloncarbonsäuren |
FR2873695A1 (fr) * | 2004-07-30 | 2006-02-03 | Palumed Sa | Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien |
GB201818410D0 (en) * | 2018-11-12 | 2018-12-26 | Imperial Innovations Ltd | Compounds |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS565484A (en) * | 1979-06-27 | 1981-01-20 | Dainippon Pharmaceut Co Ltd | Cephalosporin derivative and its salt |
JPS565485A (en) * | 1979-06-27 | 1981-01-20 | Dainippon Pharmaceut Co Ltd | Cephalosporin derivative and its salt |
ZA874696B (en) * | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
JP2676082B2 (ja) * | 1987-12-25 | 1997-11-12 | 住友化学工業株式会社 | ゴキブリ防除用マイクロカプセル剤 |
NZ227470A (en) * | 1987-12-28 | 1991-06-25 | Hoffmann La Roche | Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment |
EP0366193A3 (de) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Antimikrobielle Quinolonyllactame |
EP0366189A3 (de) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Antimikrobielle Lactam-Quinolone |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
-
1989
- 1989-10-20 EP EP89870151A patent/EP0366640B1/de not_active Expired - Lifetime
- 1989-10-20 DE DE68928925T patent/DE68928925T2/de not_active Expired - Fee Related
- 1989-10-20 AT AT89870151T patent/ATE176473T1/de not_active IP Right Cessation
- 1989-10-20 SG SG1996007907A patent/SG54293A1/en unknown
- 1989-10-20 ES ES89870151T patent/ES2129388T3/es not_active Expired - Lifetime
- 1989-10-23 CA CA002001204A patent/CA2001204A1/en not_active Abandoned
- 1989-10-24 PH PH39400A patent/PH26519A/en unknown
- 1989-10-24 KR KR1019890015236A patent/KR0139638B1/ko not_active IP Right Cessation
- 1989-10-24 AU AU43697/89A patent/AU620651B2/en not_active Ceased
- 1989-10-24 DK DK527389A patent/DK527389A/da not_active Application Discontinuation
- 1989-10-24 JP JP2501184A patent/JPH03503421A/ja active Pending
- 1989-10-24 NZ NZ231113A patent/NZ231113A/en unknown
- 1989-10-24 WO PCT/US1989/004768 patent/WO1990004595A1/en unknown
-
1999
- 1999-04-26 GR GR990401132T patent/GR3030052T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH03503421A (ja) | 1991-08-01 |
DK527389A (da) | 1990-04-25 |
CA2001204A1 (en) | 1990-04-24 |
AU620651B2 (en) | 1992-02-20 |
GR3030052T3 (en) | 1999-07-30 |
EP0366640B1 (de) | 1999-02-03 |
NZ231113A (en) | 1992-06-25 |
AU4369789A (en) | 1990-04-26 |
DK527389D0 (da) | 1989-10-24 |
EP0366640A3 (de) | 1992-01-02 |
PH26519A (en) | 1992-08-07 |
KR900006347A (ko) | 1990-05-08 |
EP0366640A2 (de) | 1990-05-02 |
KR0139638B1 (ko) | 1998-06-01 |
ATE176473T1 (de) | 1999-02-15 |
SG54293A1 (en) | 1998-11-16 |
ES2129388T3 (es) | 1999-06-16 |
DE68928925T2 (de) | 1999-08-26 |
WO1990004595A1 (en) | 1990-05-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE68928925T2 (de) | Antimikrobielle Fluorochinolonylcephemderivate | |
PT778277E (pt) | Derivados heterociclicos substituidos como antagonistas do crf | |
DE19875001I2 (de) | Antibakterielle Chinolin-Verbindungen | |
ATE119774T1 (de) | Imidazopyridinderivate und ihre verwendung. | |
DE3777735D1 (de) | Imid-derivate, ihre herstellung und ihre verwendung. | |
ES543689A0 (es) | Derivados de cefalosporina | |
NO864746D0 (no) | Fremgangsmaate for fremstilling av antibakterielle cefalosporin-derivater. | |
MY106270A (en) | Novel antimicrobial fluoroquinolonyl cephems. | |
NO893039D0 (no) | Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler. | |
ES2157952T3 (es) | Preparacion de derivados de beta-lactama e intermediarios. | |
TW257758B (en) | Piperazine derivatives (1) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |