DE68927059D1 - In-situ-unterdrückungs-hybridisierung und verwendungen - Google Patents

In-situ-unterdrückungs-hybridisierung und verwendungen

Info

Publication number
DE68927059D1
DE68927059D1 DE68927059T DE68927059T DE68927059D1 DE 68927059 D1 DE68927059 D1 DE 68927059D1 DE 68927059 T DE68927059 T DE 68927059T DE 68927059 T DE68927059 T DE 68927059T DE 68927059 D1 DE68927059 D1 DE 68927059D1
Authority
DE
Germany
Prior art keywords
chromosomes
hybridization
situ suppression
situ
suppression hybridization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68927059T
Other languages
English (en)
Other versions
DE68927059T3 (de
DE68927059T2 (de
Inventor
David Ward
Peter Lichter
Thomas Cremer
Laura Manuelidis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23036299&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68927059(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yale University filed Critical Yale University
Publication of DE68927059D1 publication Critical patent/DE68927059D1/de
Application granted granted Critical
Publication of DE68927059T2 publication Critical patent/DE68927059T2/de
Publication of DE68927059T3 publication Critical patent/DE68927059T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE68927059T 1988-11-15 1989-11-15 In-situ-unterdrückungs-hybridisierung und verwendungen Expired - Lifetime DE68927059T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27160988A 1988-11-15 1988-11-15
PCT/US1989/005253 WO1990005789A1 (en) 1988-11-15 1989-11-15 In situ suppression hybridization and uses therefor

Publications (3)

Publication Number Publication Date
DE68927059D1 true DE68927059D1 (de) 1996-10-02
DE68927059T2 DE68927059T2 (de) 1997-01-30
DE68927059T3 DE68927059T3 (de) 2001-05-10

Family

ID=23036299

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927059T Expired - Lifetime DE68927059T3 (de) 1988-11-15 1989-11-15 In-situ-unterdrückungs-hybridisierung und verwendungen

Country Status (10)

Country Link
EP (1) EP0444115B2 (de)
JP (2) JP3871066B2 (de)
CN (1) CN1046392A (de)
AT (1) ATE141957T1 (de)
AU (1) AU4642089A (de)
CA (1) CA2003051C (de)
DE (1) DE68927059T3 (de)
ES (1) ES2018959A6 (de)
IL (1) IL92323A (de)
WO (1) WO1990005789A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985549A (en) * 1985-10-22 1999-11-16 University Of Massachusetts Non-isotopic in-situ hybridization method for detection of nucleic acids
US6872817B1 (en) 1986-01-16 2005-03-29 The Regents Of The Univ. Of California Method of staining target interphase chromosomal DNA
US7115709B1 (en) 1986-01-16 2006-10-03 The Regents Of The University Of California Methods of staining target chromosomal DNA employing high complexity nucleic acid probes
US6475720B1 (en) 1986-01-16 2002-11-05 The Regents Of The University Of California Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
US5721098A (en) * 1986-01-16 1998-02-24 The Regents Of The University Of California Comparative genomic hybridization
US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US5447841A (en) * 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US6280929B1 (en) 1986-01-16 2001-08-28 The Regents Of The University Of California Method of detecting genetic translocations identified with chromosomal abnormalities
US6242184B1 (en) 1988-10-18 2001-06-05 University Of Massachusetts In-situ hybridization of single-copy and multiple-copy nucleic acid sequences
US8592155B2 (en) 1989-07-19 2013-11-26 The Regents Of The University Of California Method of detecting genetic deletions identified with chromosomal abnormalities
AU647741B2 (en) * 1989-12-01 1994-03-31 Regents Of The University Of California, The Methods and compositions for chromosome-specific staining
US6277569B1 (en) 1990-09-20 2001-08-21 Vysis, Inc. Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization
US5512433A (en) * 1990-11-08 1996-04-30 Vysis, Inc. Methods and compounds for labeling DNA with xanthine and lower alkyl substituted xanthine derivatives and reagents for the in situ detection of chromosomes
US5538869A (en) * 1990-12-13 1996-07-23 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
WO1992010566A1 (en) * 1990-12-13 1992-06-25 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
CA2060267A1 (en) * 1991-02-22 1992-08-23 Joe W. Gray Chromosome specific staining to detect genetic rearrangements
US6025126A (en) 1991-10-28 2000-02-15 Arch Development Corporation Methods and compositions for the detection of chromosomal aberrations
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US7534567B2 (en) 1992-03-04 2009-05-19 The Regents Of The University Of California Detection of nucleic acid sequence differences by comparative genomic hybridization
US5856097A (en) 1992-03-04 1999-01-05 The Regents Of The University Of California Comparative genomic hybridization (CGH)
CA2131543C (en) 1992-03-04 2002-09-17 Daniel Pinkel Comparative genomic hybridization
EP0635067A1 (de) * 1992-04-09 1995-01-25 Ig Laboratories Inc. Sonden zum nachweis von gemeinsamen chromosomalen aneuploiden in lebendgeborenen
AU5355594A (en) * 1992-10-09 1994-05-09 Oncor, Inc. Methods for the detection of chromosome structural abnormalities by (in situ) hybridization to fixed tissue
US6277606B1 (en) 1993-11-09 2001-08-21 Cold Spring Harbor Laboratory Representational approach to DNA analysis
US5436142A (en) * 1992-11-12 1995-07-25 Cold Spring Harbor Laboratory Methods for producing probes capable of distingushing variant genomic sequences
US5472842A (en) * 1993-10-06 1995-12-05 The Regents Of The University Of California Detection of amplified or deleted chromosomal regions
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
US5801021A (en) * 1995-10-20 1998-09-01 The Regents Of The University Of California Amplifications of chromosomal region 20q13 as a prognostic indicator in breast cancer
US7049424B2 (en) 1996-07-15 2006-05-23 The Regents Of The University Of California Genes from the 20Q13 amplicon and their uses
US6007994A (en) 1995-12-22 1999-12-28 Yale University Multiparametric fluorescence in situ hybridization
US5759781A (en) * 1995-12-22 1998-06-02 Yale University Multiparametric fluorescence in situ hybridization
US5792610A (en) * 1996-05-01 1998-08-11 Biorad Laboratories, Inc. Method for conducting multiparametric fluorescence in situ hybridization
US6043039A (en) * 1998-02-17 2000-03-28 Applied Spectral Imaging Method of and composite for in situ fluorescent hybridization
DE10037506A1 (de) * 2000-08-01 2002-02-14 Giesing Michael Verfahren zum Nachweis von Nukleinsäuren mittels Hybridisierung, Verwendung dieses Verfahrens und entsprechender Analysekit sowie Nukleinsäure-Oligomere und deren Verwendung
CA2441878A1 (en) 2001-03-19 2002-09-26 Ikonisys, Inc. System and method for increasing the contrast of an image produced by an epifluorescence microscope
CA2447320A1 (en) 2001-05-14 2002-11-21 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish)
EP1432826B1 (de) 2001-09-24 2012-12-12 Life Technologies Corporation Verfahren, reagentiensätze und zusammensetzungen zur unterdrückung der bindung von detektierbaren sonden an zufällig verteillten repeat sequenzen in genomischen nukleinsäuren
JP2006501449A (ja) 2002-09-27 2006-01-12 ザ ジェネラル ホスピタル コーポレーション 細胞分離のためのマイクロ流体デバイスおよびその使用
WO2005079474A2 (en) 2004-02-17 2005-09-01 The Regents Of The University Of California Detection of nucleic acid sequence differences by comparative genomic hybridization
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
DK3109324T5 (en) * 2015-06-23 2019-02-11 Zytovision Gmbh PROCEDURE FOR THE DETECTION OF CHROMOSOMA DIFFERENCES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503272A (ja) * 1986-02-21 1988-12-02 ホワイトヘッド　インスチチュ−ト　フォア−　バイオメディカル　リサ−チ Ｙ特異的ｄｎａハイブリダイゼ−シヨンプロ−ブおよびその使用
WO1988001300A1 (en) * 1986-08-12 1988-02-25 The Australian National University Sex determination in ruminants using y-chromosome specific polynucleotides
US5064948A (en) * 1988-02-12 1991-11-12 The United States Of America As Represented By The Department Of Energy Chromosome specific repetitive dna sequences

Also Published As

Publication number Publication date
JP2005245452A (ja) 2005-09-15
DE68927059T3 (de) 2001-05-10
CN1046392A (zh) 1990-10-24
IL92323A (en) 1995-10-31
ES2018959A6 (es) 1991-05-16
AU4642089A (en) 1990-06-12
ATE141957T1 (de) 1996-09-15
EP0444115A1 (de) 1991-09-04
DE68927059T2 (de) 1997-01-30
JP3871066B2 (ja) 2007-01-24
CA2003051C (en) 2004-03-02
CA2003051A1 (en) 1990-05-15
IL92323A0 (en) 1990-07-26
WO1990005789A1 (en) 1990-05-31
EP0444115B1 (de) 1996-08-28
JPH04502855A (ja) 1992-05-28
EP0444115B2 (de) 2000-12-13

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Legal Events

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8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings