DE68923616D1 - Reduzierbare indikatoren, die pyrogallol enthalten und deren verwendung. - Google Patents

Reduzierbare indikatoren, die pyrogallol enthalten und deren verwendung.

Info

Publication number
DE68923616D1
DE68923616D1 DE68923616T DE68923616T DE68923616D1 DE 68923616 D1 DE68923616 D1 DE 68923616D1 DE 68923616 T DE68923616 T DE 68923616T DE 68923616 T DE68923616 T DE 68923616T DE 68923616 D1 DE68923616 D1 DE 68923616D1
Authority
DE
Germany
Prior art keywords
analyte
pyrogallol
composition
reducable
determining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68923616T
Other languages
English (en)
Other versions
DE68923616T2 (de
Inventor
Lee Bouse
Michael Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Operations Inc
Original Assignee
Boehringer Mannheim Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Corp filed Critical Boehringer Mannheim Corp
Application granted granted Critical
Publication of DE68923616D1 publication Critical patent/DE68923616D1/de
Publication of DE68923616T2 publication Critical patent/DE68923616T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/10—Benzidines
    • C12Q2326/12—3,3',5,5'-Tetramethylbenzidine, i.e. TMB

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
DE68923616T 1988-05-25 1989-05-16 Reduzierbare indikatoren, die pyrogallol enthalten und deren verwendung. Expired - Lifetime DE68923616T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/198,765 US4971918A (en) 1988-05-25 1988-05-25 Reducible indicator compositions containing pyrogallol derivatives
PCT/US1989/002109 WO1989011643A1 (en) 1988-05-25 1989-05-16 Reducible indicators containing pyrogallol and use thereof

Publications (2)

Publication Number Publication Date
DE68923616D1 true DE68923616D1 (de) 1995-08-31
DE68923616T2 DE68923616T2 (de) 1996-02-01

Family

ID=22734747

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68923616T Expired - Lifetime DE68923616T2 (de) 1988-05-25 1989-05-16 Reduzierbare indikatoren, die pyrogallol enthalten und deren verwendung.

Country Status (8)

Country Link
US (1) US4971918A (de)
EP (1) EP0420893B1 (de)
JP (1) JPH03505628A (de)
AT (1) ATE125623T1 (de)
AU (1) AU3765989A (de)
CA (1) CA1339795C (de)
DE (1) DE68923616T2 (de)
WO (1) WO1989011643A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260195A (en) * 1991-01-03 1993-11-09 Boehringer Mannheim Corporation Nonaqueous polymeric reagent compositions and applications thereof
CA2129839A1 (en) * 1992-02-10 1993-08-19 David J. Gibboni Method for immobilizing dye on substrates
US5518891A (en) * 1993-03-25 1996-05-21 Actimed Laboratories, Inc. Dye forming composition and detection of hydrogen peroxide therewith
US5468236A (en) * 1993-06-09 1995-11-21 Kimberly-Clark Corporation Disposable absorbent product incorporating chemically reactive substance
DE102005055633B3 (de) * 2005-11-22 2007-06-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Organobasierter Sauerstoff-Scavenger/-Indikator
CA3000297C (en) * 2015-11-23 2021-11-02 F. Hoffmann-La Roche Ag Method and apparatus for determining the concentration of an analyte in a body fluid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3413197A (en) * 1966-06-30 1968-11-26 Miles Lab Controlled sensitivity galactose test composition and process
US4042335A (en) * 1975-07-23 1977-08-16 Eastman Kodak Company Integral element for analysis of liquids
US4291121A (en) * 1979-04-13 1981-09-22 Miles Laboratories, Inc. Bilirubin-resistant determination of uric acid and cholesterol
JPS5939307B2 (ja) * 1980-06-18 1984-09-21 三菱瓦斯化学株式会社 プラスチツク物品
JPS57174099A (en) * 1981-04-17 1982-10-26 Fuji Photo Film Co Ltd Color indicator composition for detecting hydrogen peroxide and quantitative analytical film having reagent layer containing the same
US4396579A (en) * 1981-08-06 1983-08-02 Miles Laboratories, Inc. Luminescence detection device
US4447542A (en) * 1983-04-04 1984-05-08 Miles Laboratories, Inc. Analytical test composition, device and method for the determination of peroxidatively active substances
GB8410548D0 (en) * 1984-04-25 1984-05-31 Ciba Geigy Ag Colourable assembly
US4680259A (en) * 1984-09-26 1987-07-14 Eastman Kodak Company Analytical element and method for colorimetric determination of total cholesterol
US4857271A (en) * 1985-02-07 1989-08-15 Eastman Kodak Company Reducible compounds and analytical compositions, elements and methods utilizing same

Also Published As

Publication number Publication date
JPH03505628A (ja) 1991-12-05
EP0420893A1 (de) 1991-04-10
WO1989011643A1 (en) 1989-11-30
DE68923616T2 (de) 1996-02-01
US4971918A (en) 1990-11-20
CA1339795C (en) 1998-04-07
AU3765989A (en) 1989-12-12
EP0420893B1 (de) 1995-07-26
EP0420893A4 (en) 1991-09-25
ATE125623T1 (de) 1995-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US

8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS OPERATIONS, INC., INDIANAPOLIS,

8328 Change in the person/name/address of the agent

Representative=s name: DURM & PARTNER, 76137 KARLSRUHE