DE68917520D1 - Methods and systems for producing HIV antigens. - Google Patents

Methods and systems for producing HIV antigens.

Info

Publication number
DE68917520D1
DE68917520D1 DE68917520T DE68917520T DE68917520D1 DE 68917520 D1 DE68917520 D1 DE 68917520D1 DE 68917520 T DE68917520 T DE 68917520T DE 68917520 T DE68917520 T DE 68917520T DE 68917520 D1 DE68917520 D1 DE 68917520D1
Authority
DE
Germany
Prior art keywords
methods
systems
hiv antigens
producing hiv
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68917520T
Other languages
German (de)
Other versions
DE68917520T2 (en
Inventor
Michael F Nunn
Torsten B Helting
Hakan Drevin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HELTING, TORSTEN B., SAN FRANCISCO, CALIF., US
Original Assignee
FERROPAS AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FERROPAS AG filed Critical FERROPAS AG
Publication of DE68917520D1 publication Critical patent/DE68917520D1/en
Application granted granted Critical
Publication of DE68917520T2 publication Critical patent/DE68917520T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to a DNA segment encoding a recombinant HIV p24 protein or HIV p24-gp41 fusion protein and a recombinant DNA (rDNA) molecule capable of expressing either protein. Cells transformed with the rDNA, methods for producing the fusion protein and diagnostic methods and systems using the fusion protein are also described.
DE68917520T 1988-05-06 1989-05-02 Methods and systems for producing HIV antigens. Expired - Fee Related DE68917520T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19122988A 1988-05-06 1988-05-06
US20649988A 1988-06-13 1988-06-13
US25801688A 1988-10-14 1988-10-14

Publications (2)

Publication Number Publication Date
DE68917520D1 true DE68917520D1 (en) 1994-09-22
DE68917520T2 DE68917520T2 (en) 1995-01-05

Family

ID=27392872

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917520T Expired - Fee Related DE68917520T2 (en) 1988-05-06 1989-05-02 Methods and systems for producing HIV antigens.

Country Status (4)

Country Link
EP (1) EP0343132B1 (en)
AT (1) ATE110112T1 (en)
DE (1) DE68917520T2 (en)
ES (1) ES2059823T3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817318A (en) * 1989-05-03 1998-10-06 Connaught Laboratories Limited Synthetic peptides for an HIV-1 vaccine
DE69131513T3 (en) * 1990-03-21 2005-05-25 Geneart Gmbh DNA sequences encoding modified retroviral GAG polypeptides and vaccines or aggregates thereof containing them
ATE199394T1 (en) * 1992-06-04 2001-03-15 Univ Osaka Res Found GAG-ENV FUSION ANTIGEN FROM HIV

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187041B1 (en) * 1984-12-24 1996-05-15 Genentech, Inc. Fusions of AIDS-related polypeptides
GR862412B (en) * 1985-09-25 1987-01-23 Oncogen Vaccines and immuinoassays for acquired immune deficiency syndrome
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DE3877294T2 (en) * 1987-09-04 1993-05-06 Int Murex Tech Corp SOLID-PHASE IMMUNOASSAY FOR AN ANTIBODY AND BIOLOGICAL PRODUCTS USED HERE.

Also Published As

Publication number Publication date
EP0343132A2 (en) 1989-11-23
ATE110112T1 (en) 1994-09-15
EP0343132B1 (en) 1994-08-17
EP0343132A3 (en) 1990-09-19
ES2059823T3 (en) 1994-11-16
DE68917520T2 (en) 1995-01-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HELTING, TORSTEN B., SAN FRANCISCO, CALIF., US

8320 Willingness to grant licences declared (paragraph 23)
8339 Ceased/non-payment of the annual fee