DE68912758D1 - Wundheilung. - Google Patents

Wundheilung.

Info

Publication number
DE68912758D1
DE68912758D1 DE89910545T DE68912758T DE68912758D1 DE 68912758 D1 DE68912758 D1 DE 68912758D1 DE 89910545 T DE89910545 T DE 89910545T DE 68912758 T DE68912758 T DE 68912758T DE 68912758 D1 DE68912758 D1 DE 68912758D1
Authority
DE
Germany
Prior art keywords
wound healing
healing
wound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89910545T
Other languages
English (en)
Other versions
DE68912758T2 (de
Inventor
Harry Antoniades
Sammuel Lynch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Institute of Molecular Biology Inc
Original Assignee
Harvard College
Institute of Molecular Biology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Institute of Molecular Biology Inc filed Critical Harvard College
Publication of DE68912758D1 publication Critical patent/DE68912758D1/de
Application granted granted Critical
Publication of DE68912758T2 publication Critical patent/DE68912758T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE68912758T 1988-08-10 1989-08-10 Wundheilung. Expired - Lifetime DE68912758T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/231,145 US5034375A (en) 1988-08-10 1988-08-10 Process of wound healing using PDGF and EGF
PCT/US1989/003490 WO1990001331A1 (en) 1988-08-10 1989-08-10 Wound healing

Publications (2)

Publication Number Publication Date
DE68912758D1 true DE68912758D1 (de) 1994-03-10
DE68912758T2 DE68912758T2 (de) 1994-06-01

Family

ID=22867921

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68912758T Expired - Lifetime DE68912758T2 (de) 1988-08-10 1989-08-10 Wundheilung.

Country Status (7)

Country Link
US (1) US5034375A (de)
EP (1) EP0382841B1 (de)
JP (1) JPH075481B2 (de)
AU (1) AU4319789A (de)
CA (1) CA1336816C (de)
DE (1) DE68912758T2 (de)
WO (1) WO1990001331A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242902A (en) * 1989-09-06 1993-09-07 The Regents Of The University Of California Defensin peptide compositions and methods for their use
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
DE69132918T2 (de) * 1990-11-27 2002-10-31 American National Red Cross, Washington Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung
US7229959B1 (en) 1990-11-27 2007-06-12 The American National Red Cross Supplemented fibrin matrix delivery systems
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
JPH04305528A (ja) * 1991-02-22 1992-10-28 Dai Ichi Seiyaku Co Ltd ケラチノサイト及び皮膚線維芽細胞の増殖刺激剤
US5591709A (en) * 1991-08-30 1997-01-07 Life Medical Sciences, Inc. Compositions and methods for treating wounds
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
EP0639980A1 (de) * 1992-02-26 1995-03-01 Allergan, Inc. Verwendung von wachstumsfaktor, abstammend von blutplättchen, zur ophthalmischen wundheilung
JP3952508B2 (ja) * 1993-11-09 2007-08-01 ニューロスフィアーズ ホウルディングス リミテッド 中枢神経系の幹細胞の原位置修飾及び操作
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
DE10014557A1 (de) * 2000-03-23 2001-10-04 Lohmann Therapie Syst Lts Wundauflage mit verminderter Verwachsungstendenz
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
HK1077740A1 (en) * 2001-12-20 2006-02-24 Ct Ingenieria Genetica Biotech Use of epidermal growth factor in the manufacture of a pharmaceutical injection composition for preventing diabetic limb amputation
TWI348912B (en) * 2002-03-12 2011-09-21 Method and composition for treating skin wounds with epidermal growth factor
CA2498212C (en) 2002-09-10 2012-07-17 American National Red Cross Multi-layered hemostatic dressing comprising thrombin and fibrinogen
DE102004018347A1 (de) * 2004-04-06 2005-10-27 Manfred Dr. Schmolz Wundheilungsfördende Botenstoffmischung
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
NZ571113A (en) * 2005-11-17 2012-02-24 Biomimetic Therapeutics Inc Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
CU23388B6 (es) 2006-01-31 2009-07-16 Ct Ingenieria Genetica Biotech Composición farmacéutica de microesferas para prevenir la amputación del pie diabético
EP2311505B1 (de) 2006-02-09 2013-11-06 BioMimetic Therapeutics, LLC Zusammensetzungen und Verfahren zur Behandlung von Knochen
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007269712B2 (en) 2006-06-30 2013-02-07 Biomimetic Therapeutics, Llc PDGF-biomatrix compositions and methods for treating rotator cuff injuries
WO2008019129A2 (en) * 2006-08-04 2008-02-14 Stb Lifesaving Technologies, Inc. Solid dressing for treating wounded tissue
EP2462895B1 (de) 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Zusammensetzungen und Verfahren für Behandlungen von Arthodese
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
US20090075891A1 (en) * 2007-08-06 2009-03-19 Macphee Martin Methods and dressings for sealing internal injuries
WO2009052221A2 (en) * 2007-10-15 2009-04-23 The Regents Of The University Of Colorado Methods for extracting platelets and compositions obtained therefrom
JP5864106B2 (ja) 2008-02-07 2016-02-17 バイオミメティック セラピューティクス, エルエルシー 仮骨延長のための組成物および方法
NZ602861A (en) * 2008-09-09 2014-03-28 Biomimetic Therapeutics Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
AU2011217784B2 (en) 2010-02-22 2014-10-09 Biomimetic Therapeutics, Llc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
WO2013077641A1 (ko) * 2011-11-22 2013-05-30 (주)아모레퍼시픽 성장 인자를 포함하는 피부 재생 촉진제
EP2821077A1 (de) * 2013-07-04 2015-01-07 Praxis Biopharma Research Institute Lipid-Nanopartikel zur Wundheilung
WO2015063613A2 (en) 2013-11-01 2015-05-07 Spherium Biomed S.L. Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents
JP6871855B2 (ja) 2014-10-14 2021-05-19 サムエル リンチ, 創傷を処置するための組成物
KR101777910B1 (ko) * 2015-04-30 2017-09-13 주식회사 제네웰 만성창상 치료용 조성물, 이의 제조방법 및 이를 이용한 만성창상 치료용 드레싱재
KR101924409B1 (ko) * 2016-08-31 2018-12-03 연세대학교 산학협력단 상처 치료용 약학 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2558537C2 (de) * 1975-12-24 1984-07-19 Hellmut Dr. 8000 München Mittenzwei Verfahren zum Isolieren von Substanzen mit insulinähnlicher Wirksamkeit aus Blut oder Blutbestandteilen von Kälbern oder Schweinen
US4350687A (en) * 1980-02-10 1982-09-21 Research Corporation Platelet derived cell growth factor
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
JPS6028999A (ja) * 1983-06-30 1985-02-14 Maruho Kk 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法
EP0154434B1 (de) * 1984-02-17 1993-01-27 Genentech, Inc. Menschlicher Transformationswachstumsfaktor und Vorläufer oder Fragment hiervon, Zellen, DNA, Vektoren und Verfahren zu ihrer Herstellung, Zusammensetzungen und Produkte, die diese enthalten, sowie davon abgeleitete Antikörper und Diagnostizierverfahren
US4745179A (en) * 1984-04-02 1988-05-17 Fujisawa Pharmaceutical Co., Ltd. 59 Valine insulin-like growth factor I and process for production thereof
US4702908A (en) * 1985-11-01 1987-10-27 Thorbecke G Jeanette Composition containing platelet factor 4 and method for restoring suppressed immune responses
NZ235556A (en) * 1986-11-05 1991-06-25 Ethicon Inc Breast milk substitute containing recombinant human egf
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor

Also Published As

Publication number Publication date
EP0382841A1 (de) 1990-08-22
AU4319789A (en) 1990-03-05
US5034375A (en) 1991-07-23
WO1990001331A1 (en) 1990-02-22
EP0382841A4 (en) 1991-01-02
JPH075481B2 (ja) 1995-01-25
CA1336816C (en) 1995-08-29
EP0382841B1 (de) 1994-01-26
DE68912758T2 (de) 1994-06-01
JPH03500782A (ja) 1991-02-21

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Legal Events

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8364 No opposition during term of opposition