DE68907566D1 - Phenoxy- und phenylthio-, amino-substituierte benzocyclo-alkan-derivate bei der behandlung und verhuetung von arzneimittelresistenten protozoen-infektionen. - Google Patents

Phenoxy- und phenylthio-, amino-substituierte benzocyclo-alkan-derivate bei der behandlung und verhuetung von arzneimittelresistenten protozoen-infektionen.

Info

Publication number
DE68907566D1
DE68907566D1 DE8989122133T DE68907566T DE68907566D1 DE 68907566 D1 DE68907566 D1 DE 68907566D1 DE 8989122133 T DE8989122133 T DE 8989122133T DE 68907566 T DE68907566 T DE 68907566T DE 68907566 D1 DE68907566 D1 DE 68907566D1
Authority
DE
Germany
Prior art keywords
drug
resistant
prevention
treatment
benzocyclo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989122133T
Other languages
English (en)
Other versions
DE68907566T2 (de
Inventor
Alan J Bitonti
Jules Freedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE68907566D1 publication Critical patent/DE68907566D1/de
Application granted granted Critical
Publication of DE68907566T2 publication Critical patent/DE68907566T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE89122133T 1988-12-01 1989-11-30 Phenoxy- und phenylthio-, amino-substituierte Benzocyclo-alkan-Derivate bei der Behandlung und Verhütung von arzneimittelresistenten Protozoen-Infektionen. Expired - Lifetime DE68907566T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27868988A 1988-12-01 1988-12-01

Publications (2)

Publication Number Publication Date
DE68907566D1 true DE68907566D1 (de) 1993-08-19
DE68907566T2 DE68907566T2 (de) 1993-12-09

Family

ID=23065966

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89122133T Expired - Lifetime DE68907566T2 (de) 1988-12-01 1989-11-30 Phenoxy- und phenylthio-, amino-substituierte Benzocyclo-alkan-Derivate bei der Behandlung und Verhütung von arzneimittelresistenten Protozoen-Infektionen.

Country Status (11)

Country Link
US (1) US5134168A (de)
EP (1) EP0371508B1 (de)
JP (1) JP2867153B2 (de)
KR (1) KR0150630B1 (de)
AT (1) ATE91415T1 (de)
AU (1) AU622244B2 (de)
DE (1) DE68907566T2 (de)
DK (1) DK605589A (de)
ES (1) ES2058451T3 (de)
IE (1) IE62013B1 (de)
ZA (1) ZA899033B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA923283B (en) * 1991-05-29 1993-01-27 Akzo Nv Phenoxyphenyl derivatives
GB9315600D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Compounds
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
US5436243A (en) * 1993-11-17 1995-07-25 Research Triangle Institute Duke University Aminoanthraquinone derivatives to combat multidrug resistance
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US7108992B2 (en) * 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
EP1827405A2 (de) * 2004-11-24 2007-09-05 Algorx Pharmaceuticals, Inc. Capsaicinoid-gelformulierung und ihre verwendungen
WO2007127930A2 (en) * 2006-04-28 2007-11-08 Kansas State University Research Foundation Compounds affecting gap junction activity
US8822449B2 (en) * 2008-09-02 2014-09-02 Sanofi Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof
EP2368876A1 (de) * 2010-03-01 2011-09-28 Sanofi Derivate von Aminoindanen, deren Herstellung und deren Anwendung in der Therapeutik

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2409256A1 (fr) * 1977-11-18 1979-06-15 Roussel Uclaf Nouveaux derives de la 5h-benzocycloepten-7-amine et leurs sels, procede de preparation et application a titre de medicament
CA1327795C (en) * 1987-08-14 1994-03-15 Jules Freedman Antidepressants which are aryloxy inadanamines
CA1331191C (en) * 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives

Also Published As

Publication number Publication date
IE62013B1 (en) 1994-12-14
AU622244B2 (en) 1992-04-02
ES2058451T3 (es) 1994-11-01
DK605589D0 (da) 1989-11-30
IE893839L (en) 1990-06-01
EP0371508B1 (de) 1993-07-14
ATE91415T1 (de) 1993-07-15
DK605589A (da) 1990-06-02
JPH02184623A (ja) 1990-07-19
KR0150630B1 (ko) 1998-10-15
DE68907566T2 (de) 1993-12-09
EP0371508A1 (de) 1990-06-06
US5134168A (en) 1992-07-28
ZA899033B (en) 1990-09-26
JP2867153B2 (ja) 1999-03-08
KR900009068A (ko) 1990-07-02
AU4574689A (en) 1990-06-07

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