DE615655C - Process for the production of ointment-shaped masses - Google Patents

Process for the production of ointment-shaped masses

Info

Publication number
DE615655C
DE615655C DET42641D DET0042641D DE615655C DE 615655 C DE615655 C DE 615655C DE T42641 D DET42641 D DE T42641D DE T0042641 D DET0042641 D DE T0042641D DE 615655 C DE615655 C DE 615655C
Authority
DE
Germany
Prior art keywords
ointment
production
shaped masses
shaped
ammonium salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DET42641D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUGO WEIL DR
CHEM PHARM PRAEPARATE JOHANN T
Original Assignee
HUGO WEIL DR
CHEM PHARM PRAEPARATE JOHANN T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HUGO WEIL DR, CHEM PHARM PRAEPARATE JOHANN T filed Critical HUGO WEIL DR
Priority to DET42641D priority Critical patent/DE615655C/en
Application granted granted Critical
Publication of DE615655C publication Critical patent/DE615655C/en
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

Verfahren zur Herstellung von salbenförmigen Massen Gegenstand des Patents 587 142 ist ein Verfahren. zur Herstellung von salbenförmigen Massen. Es besteht darin, daß man auf Alkalisilicatlösungen aliphatische oder hydroaromatische Mono;aarbonsäuren mit mehr als g Kohlenstoffatomen im Molekül einwirken läßt.Process for the production of ointment-shaped masses the subject of Patent 587,142 is one process. for the production of ointment-shaped masses. It consists in using aliphatic or hydroaromatic solutions on alkali metal silicate solutions Mono; aarboxylic acids with more than g carbon atoms in the molecule can act.

Es wurde gefunden, daß man zu ganz ähnlichen Stoffen auch dann gelangt, wenn man an Stelle der freien Säuren deren Ammoniumsalze verwendet. Die Ausführung des Verfahrens -erleidet dadurch keine wesentliche Änderung, und man kann die Umsetzung sowohl bei gewöhnlicher als auch bei erhöhter Temperatur- sich vollziehen lassen. Beispiele i. io Volumteile Kaliwässerglaslösung (D. etwa i,2) werden auf 15 o Völumteile verdünnt und nach und nach bei einer Temperatur von etwa 6o° 12 Teile des Ammonium. salzes der Stearinsäure zugegeben. In -dem Maße, wie der Zusatz des Bettsaunen Salzes erfolgt, bildet sich ein flockiger Niederschlag, und beim Abkühlen erstarrt die Masse zur Salbenkonsistenz.It has been found that very similar substances can also be obtained if their ammonium salts are used instead of the free acids. The execution of the process does not suffer any significant change, and the reaction can be carried out at both normal and elevated temperatures. Examples i. io parts by volume Kaliwässerglaslösung (D. about i, 2) are diluted to 1 o Völumteile 5 and gradually at a temperature of about 12 parts of the ammonium 6o °. salt of stearic acid added. As the bed sauna salt is added, a flaky precipitate forms, and when it cools down, the mass solidifies to the consistency of an ointment.

2. Verwendet man an Stelle des Kaliwasserglases Natronwasserglas (D. 43) und verfährt im übrigen in der gleichen Weise, so erhält man eine salbenförmige Masse von etwa der gleichen Beschaffenheit.2. If you use soda water glass (D. 43) and proceeding in the same way, one obtains an ointment-shaped one Mass of roughly the same consistency.

3. =Verwendet man statt der i o Volumteile der Sslicatlösung etwa 3 0 Volumteile derselben von der angegebenen Dichte, so bedarf man auch ungefähr der dreifachen Menge des stearinsanren Salzes zur Umsetzung. Die Bildung der salbenförmigen Masse beginnt dann schon in der Hitze.3 = is used instead of the io parts by volume of Sslicatlösung about 3 0 parts by volume of the same by the specified density to three times the amount of the stearinsanren salt for the reaction is also needed about. The formation of the ointment-shaped mass then begins in the heat.

q.. Man kann in den obigen Beispielen das Ammoniumsalz der Stearinsäure ganz oder teilweise durch die Ammonsal.ze von Myristin-, Pahnitin-, öl- oder Naphthensäure ersetzen und im übrigen in gleicher Weisse verfahren.q .. You can use the ammonium salt of stearic acid in the above examples in whole or in part by the ammonium salts of myristic, pahnitic, oleic or naphthenic acid replace and otherwise proceed in the same way.

In den obigen Beispielen können die Mengen des Lösungsmittels, die Temperatur, die Menge und Art der angewendeten Säuren in weiten Grenzen wechselnd gehalten werden. Man kann natürlich auch Gemische der genannten Amm@onsalze verwenden.In the above examples, the amounts of solvent that Temperature, the amount and type of acids used vary within wide limits being held. It is of course also possible to use mixtures of the ammonium salts mentioned.

Claims (1)

PATENTANSPRUCH: Weiterbildung des Verfahrens zur Herstellung salbenförmiger Massen nach Patent 581142, dadurch gekennzeichnet, da,ß man hier die Ammoniumsalze der aliphatischen ioder hydroaromatischen Monocarbionsäuren auf die Alkalislicatlösung en ,einwirken läßt.PATENT CLAIM: Further development of the method for producing ointment-shaped masses according to Patent 581 142, characterized in that the ammonium salts of the aliphatic or hydroaromatic monocarbionic acids are allowed to act on the alkali licate solution.
DET42641D 1933-06-13 1933-06-13 Process for the production of ointment-shaped masses Expired DE615655C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DET42641D DE615655C (en) 1933-06-13 1933-06-13 Process for the production of ointment-shaped masses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DET42641D DE615655C (en) 1933-06-13 1933-06-13 Process for the production of ointment-shaped masses

Publications (1)

Publication Number Publication Date
DE615655C true DE615655C (en) 1935-07-09

Family

ID=7561322

Family Applications (1)

Application Number Title Priority Date Filing Date
DET42641D Expired DE615655C (en) 1933-06-13 1933-06-13 Process for the production of ointment-shaped masses

Country Status (1)

Country Link
DE (1) DE615655C (en)

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