DE60334499D1 - Verfahren zur erhöhung der ausbreitung von b-zellen - Google Patents
Verfahren zur erhöhung der ausbreitung von b-zellenInfo
- Publication number
- DE60334499D1 DE60334499D1 DE60334499T DE60334499T DE60334499D1 DE 60334499 D1 DE60334499 D1 DE 60334499D1 DE 60334499 T DE60334499 T DE 60334499T DE 60334499 T DE60334499 T DE 60334499T DE 60334499 D1 DE60334499 D1 DE 60334499D1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- increasing
- methods
- spread
- proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 7
- 102100037632 Progranulin Human genes 0.000 abstract 1
- 101710114165 Progranulin Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 231100001221 nontumorigenic Toxicity 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000000284 resting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44959303P | 2003-02-26 | 2003-02-26 | |
PCT/US2003/040111 WO2004078782A1 (en) | 2003-02-26 | 2003-12-17 | Methods for increasing the proliferation of b cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60334499D1 true DE60334499D1 (de) | 2010-11-18 |
Family
ID=32962489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60334499T Expired - Lifetime DE60334499D1 (de) | 2003-02-26 | 2003-12-17 | Verfahren zur erhöhung der ausbreitung von b-zellen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7651854B2 (de) |
EP (1) | EP1601687B1 (de) |
JP (1) | JP4488903B2 (de) |
AT (1) | ATE483724T1 (de) |
AU (1) | AU2003297217B2 (de) |
CA (1) | CA2517140C (de) |
DE (1) | DE60334499D1 (de) |
ES (1) | ES2369695T3 (de) |
WO (1) | WO2004078782A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030215445A1 (en) | 1997-05-23 | 2003-11-20 | Ginette Serrero | Methods and compositions for inhibiting the growth of hematopoietic malignant cells |
US20100111928A1 (en) * | 1997-05-23 | 2010-05-06 | A & G Pharmaceutical, Inc. | Methods and kits for diagnosis tumorgenicity |
US7411045B2 (en) * | 2002-11-19 | 2008-08-12 | A&G Pharmaceutical, Inc. | Autocrine growth factor receptor antibodies and methods |
CA2517140C (en) | 2003-02-26 | 2013-12-10 | A&G Pharmaceutical, Inc. | Use of pc-cell derived growth factor (pcdgf) for increasing the proliferation of b cells |
WO2005011590A2 (en) | 2003-08-01 | 2005-02-10 | A & G Pharmaceutical, Inc. | Compositions and methods for restoring sensitivity to treatment with her2 antagonists |
GB0502046D0 (en) | 2005-02-01 | 2005-03-09 | Sinclair Pharmaceuticals Ltd | Method |
EP2687223B1 (de) * | 2006-05-30 | 2017-07-12 | Mayo Foundation For Medical Education And Research | Erkennung und Behandlung von Demenz |
CA2653974A1 (en) | 2006-05-30 | 2008-02-14 | Mayo Foundation For Medical Education And Research | Detecting and treating dementia |
DE102007033359B4 (de) * | 2007-07-16 | 2010-12-02 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Verwendung eines Granulins oder einer Granulin-ähnlichen Verbindung zur Therapie oder Prophylaxe von chronischen Schmerzen |
US20160075766A1 (en) | 2013-05-21 | 2016-03-17 | Roche Diagnostics Operations, Inc. | Method for producing antibodies using ovine b-cells and uses thereof |
ES2944563T3 (es) * | 2014-05-19 | 2023-06-22 | Hoffmann La Roche | Procedimiento para producir anticuerpos usando linfocitos B ovinos y usos de los mismos |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5416192A (en) | 1990-04-03 | 1995-05-16 | Bristol-Myers Squibb Company | Epithelins: novel cysteine-rich growth modulating proteins |
WO1993015195A1 (en) | 1992-02-03 | 1993-08-05 | Samuel Solomon | Granulins from leukocytes |
WO1994016074A2 (en) * | 1993-01-15 | 1994-07-21 | Washington University, St. Louis | High molecular weight b-cell growth factor: interleukin-14 |
US7091047B2 (en) * | 1997-05-23 | 2006-08-15 | A&G Pharmaceutical, Inc. | Methods and kits for diagnosing tumorigenicity |
US20030215445A1 (en) * | 1997-05-23 | 2003-11-20 | Ginette Serrero | Methods and compositions for inhibiting the growth of hematopoietic malignant cells |
US6720159B1 (en) * | 1997-12-16 | 2004-04-13 | A&G Pharmaceutical, Inc. | 88KDA tumorigenic growth factor and antagonists |
US6309826B1 (en) * | 1997-05-23 | 2001-10-30 | Ginette Serrero | 88kDa tumorigenic growth factor and antagonists |
US6881548B2 (en) | 1997-05-23 | 2005-04-19 | A&G Pharmaceutical, Inc. | Methods and kits for diagnosing tumorigenicity and determining resistance to the antineoplastic effects of antiestrogen therapy |
EP1318837B1 (de) * | 2000-08-11 | 2004-10-06 | Wyeth | Verfahren zur behandlung eines östrogenrezeptor positives karzinoms |
AU2002213084A1 (en) | 2000-10-11 | 2002-04-22 | Avalon Pharmaceuticals | Cancer-linked genes as targets for chemotherapy |
US7411045B2 (en) * | 2002-11-19 | 2008-08-12 | A&G Pharmaceutical, Inc. | Autocrine growth factor receptor antibodies and methods |
CA2517140C (en) | 2003-02-26 | 2013-12-10 | A&G Pharmaceutical, Inc. | Use of pc-cell derived growth factor (pcdgf) for increasing the proliferation of b cells |
WO2005000207A2 (en) | 2003-05-30 | 2005-01-06 | Medimmune, Inc. | Pcdgf receptor antibodies and methods of use thereof |
EP1644038A2 (de) * | 2003-06-23 | 2006-04-12 | A & G Pharmaceuticals, Inc. | Zusammenetzungen und verfahren zur wiederherstellung der emfpindlichkeit von tumorzellen auf eine antitumorale therapie und einleitung von apoptose |
WO2005011590A2 (en) * | 2003-08-01 | 2005-02-10 | A & G Pharmaceutical, Inc. | Compositions and methods for restoring sensitivity to treatment with her2 antagonists |
EP1812794A4 (de) * | 2004-10-13 | 2008-09-10 | A & G Pharmaceutical Inc | Autokrine wachstumsfaktor-rezeptoren und verfahren |
-
2003
- 2003-12-17 CA CA2517140A patent/CA2517140C/en not_active Expired - Fee Related
- 2003-12-17 WO PCT/US2003/040111 patent/WO2004078782A1/en active Application Filing
- 2003-12-17 US US10/546,868 patent/US7651854B2/en active Active
- 2003-12-17 JP JP2004569217A patent/JP4488903B2/ja not_active Expired - Fee Related
- 2003-12-17 EP EP03816201A patent/EP1601687B1/de not_active Expired - Lifetime
- 2003-12-17 AT AT03816201T patent/ATE483724T1/de not_active IP Right Cessation
- 2003-12-17 ES ES03816201T patent/ES2369695T3/es not_active Expired - Lifetime
- 2003-12-17 AU AU2003297217A patent/AU2003297217B2/en not_active Ceased
- 2003-12-17 DE DE60334499T patent/DE60334499D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2517140C (en) | 2013-12-10 |
AU2003297217B2 (en) | 2010-01-07 |
EP1601687B1 (de) | 2010-10-06 |
ES2369695T3 (es) | 2011-12-05 |
EP1601687A1 (de) | 2005-12-07 |
EP1601687A4 (de) | 2006-07-26 |
US20070015225A1 (en) | 2007-01-18 |
WO2004078782A1 (en) | 2004-09-16 |
US7651854B2 (en) | 2010-01-26 |
CA2517140A1 (en) | 2004-09-16 |
JP2006524484A (ja) | 2006-11-02 |
AU2003297217A1 (en) | 2004-09-28 |
ATE483724T1 (de) | 2010-10-15 |
JP4488903B2 (ja) | 2010-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8328 | Change in the person/name/address of the agent |
Representative=s name: VONNEMANN, KLOIBER & KOLLEGEN, 20099 HAMBURG |