DE60327655D1 - Verfahren zur behandlung von durch taxol induzierter sensorischer neuropathie - Google Patents
Verfahren zur behandlung von durch taxol induzierter sensorischer neuropathieInfo
- Publication number
- DE60327655D1 DE60327655D1 DE60327655T DE60327655T DE60327655D1 DE 60327655 D1 DE60327655 D1 DE 60327655D1 DE 60327655 T DE60327655 T DE 60327655T DE 60327655 T DE60327655 T DE 60327655T DE 60327655 D1 DE60327655 D1 DE 60327655D1
- Authority
- DE
- Germany
- Prior art keywords
- induced
- taxol
- neuropathy
- treating
- sensoric neuropathy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 201000001119 neuropathy Diseases 0.000 title abstract 2
- 230000007823 neuropathy Effects 0.000 title abstract 2
- 208000033808 peripheral neuropathy Diseases 0.000 title abstract 2
- 229930012538 Paclitaxel Natural products 0.000 abstract 3
- 229960001592 paclitaxel Drugs 0.000 abstract 3
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 3
- 206010034620 Peripheral sensory neuropathy Diseases 0.000 abstract 2
- 201000005572 sensory peripheral neuropathy Diseases 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43614702P | 2002-12-23 | 2002-12-23 | |
PCT/US2003/041367 WO2004058190A2 (en) | 2002-12-23 | 2003-12-23 | Methods for treating taxol-induced sensory neuropathy |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60327655D1 true DE60327655D1 (de) | 2009-06-25 |
Family
ID=32682348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60327655T Expired - Lifetime DE60327655D1 (de) | 2002-12-23 | 2003-12-23 | Verfahren zur behandlung von durch taxol induzierter sensorischer neuropathie |
Country Status (10)
Country | Link |
---|---|
US (1) | US20050089521A1 (de) |
EP (1) | EP1581759B1 (de) |
JP (1) | JP2006513187A (de) |
AT (1) | ATE431157T1 (de) |
AU (1) | AU2003300397A1 (de) |
CA (1) | CA2511295A1 (de) |
DE (1) | DE60327655D1 (de) |
ES (1) | ES2326080T3 (de) |
NZ (1) | NZ540879A (de) |
WO (1) | WO2004058190A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004084836A2 (en) * | 2003-03-20 | 2004-10-07 | Rinat Neuroscience Corp. | Methods for treating taxol-induced gut disorder |
SG166768A1 (en) * | 2003-12-23 | 2010-12-29 | Rinat Neuroscience Corp | Agonist anti-trkc antibodies and methods using same |
AR054260A1 (es) * | 2005-04-26 | 2007-06-13 | Rinat Neuroscience Corp | Metodos de tratamiento de enfermedades de la neurona motora inferior y composiciones utilizadas en los mismos |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5807715A (en) * | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
US4676980A (en) * | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
US4777127A (en) * | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
IL85035A0 (en) * | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
US5219740A (en) * | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
US5422120A (en) * | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US5750373A (en) * | 1990-12-03 | 1998-05-12 | Genentech, Inc. | Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US6673776B1 (en) * | 1989-03-21 | 2004-01-06 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human |
US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5427908A (en) * | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
US5545806A (en) * | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5625126A (en) * | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5661016A (en) * | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5633425A (en) * | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
WO1992003918A1 (en) * | 1990-08-29 | 1992-03-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5604202A (en) * | 1990-11-13 | 1997-02-18 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Use of NGF growth factors to treat drug-induced neuropathy |
EP1400536A1 (de) * | 1991-06-14 | 2004-03-24 | Genentech Inc. | Verfahren zur Herstellung humanisierter Antikörper |
WO1994004679A1 (en) * | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
GB9115364D0 (en) * | 1991-07-16 | 1991-08-28 | Wellcome Found | Antibody |
CA2078539C (en) * | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
US5714350A (en) * | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
US5733743A (en) * | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
US6210671B1 (en) * | 1992-12-01 | 2001-04-03 | Protein Design Labs, Inc. | Humanized antibodies reactive with L-selectin |
US6180377B1 (en) * | 1993-06-16 | 2001-01-30 | Celltech Therapeutics Limited | Humanized antibodies |
US6015686A (en) * | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
EP0730646A1 (de) * | 1993-11-23 | 1996-09-11 | Genentech, Inc. | Rse, protein tyrosin kinasen |
AU698975B2 (en) * | 1993-11-23 | 1998-11-12 | Genentech Inc. | Kinase receptor activation assay |
US5877016A (en) * | 1994-03-18 | 1999-03-02 | Genentech, Inc. | Human trk receptors and neurotrophic factor inhibitors |
US6436908B1 (en) * | 1995-05-30 | 2002-08-20 | Duke University | Use of exogenous β-adrenergic receptor and β-adrenergic receptor kinase gene constructs to enhance myocardial function |
US6265150B1 (en) * | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
UA65542C2 (uk) * | 1996-06-25 | 2004-04-15 | Сефалон, Інк. | Спосіб пригнічення надлишкового продукування фактора некрозу пухлин альфа , спосіб полегшення шкідливих ефектів надлишкового продукування фактора некрозу пухлин альфа та спосіб лікування запального стану або захворювання, пов'язаного з фактором некрозу пухлин. |
WO1999018792A1 (en) * | 1997-10-10 | 1999-04-22 | Johns Hopkins University | Gene delivery compositions and methods |
US6252050B1 (en) * | 1998-06-12 | 2001-06-26 | Genentech, Inc. | Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method |
KR100823764B1 (ko) * | 2000-06-22 | 2008-04-21 | 제넨테크, 인크. | 아고니스트 안티-티알케이-씨 모노클로날 항체 |
AU2001286930A1 (en) * | 2000-08-30 | 2002-03-13 | The Board Of Trustees Of The Leland Stanford Junior University | Glucocorticoid blocking agents for increasing blood-brain barrier permeability |
WO2004084836A2 (en) * | 2003-03-20 | 2004-10-07 | Rinat Neuroscience Corp. | Methods for treating taxol-induced gut disorder |
AR054260A1 (es) * | 2005-04-26 | 2007-06-13 | Rinat Neuroscience Corp | Metodos de tratamiento de enfermedades de la neurona motora inferior y composiciones utilizadas en los mismos |
-
2003
- 2003-12-23 AU AU2003300397A patent/AU2003300397A1/en not_active Abandoned
- 2003-12-23 EP EP03814397A patent/EP1581759B1/de not_active Expired - Lifetime
- 2003-12-23 AT AT03814397T patent/ATE431157T1/de not_active IP Right Cessation
- 2003-12-23 JP JP2004562586A patent/JP2006513187A/ja active Pending
- 2003-12-23 DE DE60327655T patent/DE60327655D1/de not_active Expired - Lifetime
- 2003-12-23 US US10/745,890 patent/US20050089521A1/en not_active Abandoned
- 2003-12-23 CA CA002511295A patent/CA2511295A1/en not_active Abandoned
- 2003-12-23 ES ES03814397T patent/ES2326080T3/es not_active Expired - Lifetime
- 2003-12-23 WO PCT/US2003/041367 patent/WO2004058190A2/en active Application Filing
- 2003-12-23 NZ NZ540879A patent/NZ540879A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2004058190A3 (en) | 2005-03-10 |
AU2003300397A1 (en) | 2004-07-22 |
JP2006513187A (ja) | 2006-04-20 |
EP1581759A4 (de) | 2006-08-02 |
WO2004058190A2 (en) | 2004-07-15 |
NZ540879A (en) | 2008-08-29 |
EP1581759B1 (de) | 2009-05-13 |
ES2326080T3 (es) | 2009-09-30 |
US20050089521A1 (en) | 2005-04-28 |
ATE431157T1 (de) | 2009-05-15 |
CA2511295A1 (en) | 2004-07-15 |
EP1581759A2 (de) | 2005-10-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE250932T1 (de) | Verfahren zur behandlung von chronischem schmerz durch verabreichung von einem mek hemmer | |
TW200716673A (en) | Use of TNF &ahr; inhibitor for treatment of erosive polyarthritis | |
DE60102016D1 (de) | Verfahren zur behandlung von beweggungsstörungen | |
DE602006019753D1 (de) | Verfahren und gerät zur behandlung von aneurysmen der a. thoracica | |
DE60122532D1 (de) | Verfahren zur behandlung von mehreren bohrlochintervallen | |
DE60335921D1 (de) | Thrombusdetektor, vorrichtung zur behandlung von thromben und verfahren dafür | |
DE60120520D1 (de) | Verfahren zur behandlung von abwasser | |
DE602004021790D1 (de) | Verfahren zur behandlung von parkinson-krankheit | |
ATE395083T1 (de) | Verfahren zur behandlung von multipler sklerose durch hemmung der il-17-aktivität | |
DE602004010381D1 (de) | Verfahren und vorrichtung zur behandlung von wasser für eine einpressbohrung | |
ATE435026T1 (de) | Verfahren zur prävention und behandlung von diabetes mit neurturin | |
ATE411018T1 (de) | Verfahren zur behandlung oder verhinderung von vaskulärer entzündung mit sterol-absorbierungs- inhibitor(en) | |
DE60310400D1 (de) | Botulinustoxine zur behandlung von priapismus | |
DE60223688D1 (de) | Verfahren zur behandlung von multiplem myelom | |
DE50104023D1 (de) | Verfahren zum auffinden von verbindungen, welche zur behandlung und/oder prophylaxe von obesitas geeignet sind | |
ATE470453T1 (de) | Verfahren zur behandlung von atherosklerose | |
DE602004004883D1 (de) | Vegf-antagonisten zur behandlung von diabetes | |
DE60219658D1 (de) | Verfahren zur prävention und behandlung von infektionen mit dem flavivirus bei tieren | |
DE60327655D1 (de) | Verfahren zur behandlung von durch taxol induzierter sensorischer neuropathie | |
DE60308045D1 (de) | Pflanzenextrakte aus argyrolobium roseum zur behandlung von diabetes | |
DE50213931D1 (de) | Verfahren und vorrichtung zur behandlung von fehlerverdacht | |
DE602004010548D1 (de) | Verfahren zur behandlung von tierhäuten | |
DE60144493D1 (de) | Verfahren zur bestimmung und behandlung von tuberöse-sklerose komplex assoziierten erkrankungen | |
DE60229123D1 (de) | Behandlung von fibromyalgie mit pindolol | |
ATA20122001A (de) | Verfahren zur behandlung von cellulosischen formkörpern |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |