DE60326214D1 - Assays zur überwachung von krebspatienten auf grundlage der spiegel von analytenkomponenten des plasminogen-aktivator-systems in proben von körperflüssigkeiten - Google Patents
Assays zur überwachung von krebspatienten auf grundlage der spiegel von analytenkomponenten des plasminogen-aktivator-systems in proben von körperflüssigkeitenInfo
- Publication number
- DE60326214D1 DE60326214D1 DE60326214T DE60326214T DE60326214D1 DE 60326214 D1 DE60326214 D1 DE 60326214D1 DE 60326214 T DE60326214 T DE 60326214T DE 60326214 T DE60326214 T DE 60326214T DE 60326214 D1 DE60326214 D1 DE 60326214D1
- Authority
- DE
- Germany
- Prior art keywords
- monitoring
- treatment
- plasminogen activator
- cancer patient
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
- G01N2333/8132—Plasminogen activator inhibitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/972—Plasminogen activators
- G01N2333/9723—Urokinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36121902P | 2002-03-01 | 2002-03-01 | |
US36865802P | 2002-03-29 | 2002-03-29 | |
PCT/US2003/005957 WO2003073910A2 (en) | 2002-03-01 | 2003-02-27 | Assays for cancer patient monitoring based on levels of analyte components of the plasminogen activator system in body fluid samples |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60326214D1 true DE60326214D1 (de) | 2009-04-02 |
Family
ID=27791665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60326214T Expired - Lifetime DE60326214D1 (de) | 2002-03-01 | 2003-02-27 | Assays zur überwachung von krebspatienten auf grundlage der spiegel von analytenkomponenten des plasminogen-aktivator-systems in proben von körperflüssigkeiten |
Country Status (7)
Country | Link |
---|---|
US (4) | US20030180819A1 (de) |
EP (1) | EP1489968B1 (de) |
AT (1) | ATE423217T1 (de) |
AU (1) | AU2003213594A1 (de) |
DE (1) | DE60326214D1 (de) |
ES (1) | ES2320115T3 (de) |
WO (1) | WO2003073910A2 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2768324B1 (fr) | 1997-09-12 | 1999-12-10 | Jacques Seguin | Instrument chirurgical permettant, par voie percutanee, de fixer l'une a l'autre deux zones de tissu mou, normalement mutuellement distantes |
US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
US7563267B2 (en) | 1999-04-09 | 2009-07-21 | Evalve, Inc. | Fixation device and methods for engaging tissue |
ES2373547T3 (es) * | 2002-02-13 | 2012-02-06 | American Diagnostica, Inc. | Métodos para seleccionar regímenes de tratamiento y predecir resultados en pacientes con cáncer de mama. |
US10646229B2 (en) | 2003-05-19 | 2020-05-12 | Evalve, Inc. | Fixation devices, systems and methods for engaging tissue |
US7635329B2 (en) | 2004-09-27 | 2009-12-22 | Evalve, Inc. | Methods and devices for tissue grasping and assessment |
US8052592B2 (en) | 2005-09-27 | 2011-11-08 | Evalve, Inc. | Methods and devices for tissue grasping and assessment |
US20090150315A1 (en) | 2005-07-29 | 2009-06-11 | Siemens Healthcare Diagnostics Inc. | Neoplastic Disease-Related Methods, Kits, Systems and Databases |
US20090142330A1 (en) * | 2007-10-15 | 2009-06-04 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | Use of inactive-plasmin to treat chronic inflammatory disease and tumors |
US8945177B2 (en) | 2011-09-13 | 2015-02-03 | Abbott Cardiovascular Systems Inc. | Gripper pusher mechanism for tissue apposition systems |
ES2754304T3 (es) | 2011-09-23 | 2020-04-16 | Siemens Healthcare Diagnostics Inc | Ensayo de respuesta celular para detectar cáncer y métodos de producción y uso del mismo |
US10390943B2 (en) | 2014-03-17 | 2019-08-27 | Evalve, Inc. | Double orifice device for transcatheter mitral valve replacement |
US10188392B2 (en) | 2014-12-19 | 2019-01-29 | Abbott Cardiovascular Systems, Inc. | Grasping for tissue repair |
US10524912B2 (en) | 2015-04-02 | 2020-01-07 | Abbott Cardiovascular Systems, Inc. | Tissue fixation devices and methods |
CA2981347A1 (en) * | 2015-04-02 | 2016-10-06 | Provista Diagnostics, Inc. | Biomarkers for detection of ovarian cancer |
US10376673B2 (en) | 2015-06-19 | 2019-08-13 | Evalve, Inc. | Catheter guiding system and methods |
US10238494B2 (en) | 2015-06-29 | 2019-03-26 | Evalve, Inc. | Self-aligning radiopaque ring |
US10667815B2 (en) | 2015-07-21 | 2020-06-02 | Evalve, Inc. | Tissue grasping devices and related methods |
US10413408B2 (en) | 2015-08-06 | 2019-09-17 | Evalve, Inc. | Delivery catheter systems, methods, and devices |
US10238495B2 (en) | 2015-10-09 | 2019-03-26 | Evalve, Inc. | Delivery catheter handle and methods of use |
US10736632B2 (en) | 2016-07-06 | 2020-08-11 | Evalve, Inc. | Methods and devices for valve clip excision |
US11071564B2 (en) | 2016-10-05 | 2021-07-27 | Evalve, Inc. | Cardiac valve cutting device |
US10363138B2 (en) | 2016-11-09 | 2019-07-30 | Evalve, Inc. | Devices for adjusting the curvature of cardiac valve structures |
US10398553B2 (en) | 2016-11-11 | 2019-09-03 | Evalve, Inc. | Opposing disk device for grasping cardiac valve tissue |
US10426616B2 (en) | 2016-11-17 | 2019-10-01 | Evalve, Inc. | Cardiac implant delivery system |
US10779837B2 (en) | 2016-12-08 | 2020-09-22 | Evalve, Inc. | Adjustable arm device for grasping tissues |
US10314586B2 (en) | 2016-12-13 | 2019-06-11 | Evalve, Inc. | Rotatable device and method for fixing tricuspid valve tissue |
US11065119B2 (en) | 2017-05-12 | 2021-07-20 | Evalve, Inc. | Long arm valve repair clip |
WO2019204741A1 (en) * | 2018-04-19 | 2019-10-24 | The Regents Of The University Of California | Method and device for detecting siglec12 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US12950A (en) * | 1855-05-29 | Fluid-faucet | ||
WO1986005807A1 (en) | 1985-04-01 | 1986-10-09 | Celltech Limited | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
US6271352B1 (en) * | 1985-07-12 | 2001-08-07 | Fonden Til Fremme Af Eksperimentel Cancerforskning | PAI-1 determination and use thereof |
US5422245A (en) * | 1985-07-12 | 1995-06-06 | Fonden Til Fremme Af Eksperimental Cancerforskning | Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for assay of the inhibitors |
GB8601597D0 (en) * | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5780225A (en) * | 1990-01-12 | 1998-07-14 | Stratagene | Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
US5427908A (en) * | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
GB9015198D0 (en) * | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
US5698426A (en) * | 1990-09-28 | 1997-12-16 | Ixsys, Incorporated | Surface expression libraries of heteromeric receptors |
ES2113940T3 (es) * | 1990-12-03 | 1998-05-16 | Genentech Inc | Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas. |
DE69233750D1 (de) * | 1991-04-10 | 2009-01-02 | Scripps Research Inst | Bibliotheken heterodimerer Rezeptoren mittels Phagemiden |
US5733743A (en) * | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
US5516637A (en) * | 1994-06-10 | 1996-05-14 | Dade International Inc. | Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage |
JP2978435B2 (ja) * | 1996-01-24 | 1999-11-15 | チッソ株式会社 | アクリロキシプロピルシランの製造方法 |
US20030032074A1 (en) * | 2001-06-01 | 2003-02-13 | Slawin Kevin M. | Methods to determine prognosis after therapy for bladder cancer |
-
2003
- 2003-02-27 DE DE60326214T patent/DE60326214D1/de not_active Expired - Lifetime
- 2003-02-27 US US10/375,646 patent/US20030180819A1/en not_active Abandoned
- 2003-02-27 AU AU2003213594A patent/AU2003213594A1/en not_active Abandoned
- 2003-02-27 WO PCT/US2003/005957 patent/WO2003073910A2/en not_active Application Discontinuation
- 2003-02-27 ES ES03711275T patent/ES2320115T3/es not_active Expired - Lifetime
- 2003-02-27 EP EP03711275A patent/EP1489968B1/de not_active Expired - Lifetime
- 2003-02-27 AT AT03711275T patent/ATE423217T1/de not_active IP Right Cessation
-
2007
- 2007-12-27 US US11/965,323 patent/US7732159B2/en not_active Expired - Fee Related
-
2009
- 2009-07-22 US US12/507,737 patent/US20090286268A1/en not_active Abandoned
-
2012
- 2012-02-28 US US13/407,641 patent/US20120220524A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1489968B1 (de) | 2009-02-18 |
EP1489968A4 (de) | 2006-08-02 |
US20030180819A1 (en) | 2003-09-25 |
AU2003213594A1 (en) | 2003-09-16 |
ATE423217T1 (de) | 2009-03-15 |
US20090286268A1 (en) | 2009-11-19 |
US7732159B2 (en) | 2010-06-08 |
US20120220524A1 (en) | 2012-08-30 |
ES2320115T3 (es) | 2009-05-19 |
WO2003073910A3 (en) | 2003-10-16 |
WO2003073910A2 (en) | 2003-09-12 |
EP1489968A2 (de) | 2004-12-29 |
US20080113392A1 (en) | 2008-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R082 | Change of representative |
Ref document number: 1489968 Country of ref document: EP Representative=s name: VEREENIGDE OCTROOIBUREAUX N.V., 80331 MUENCHEN, DE |