DE60325609D1 - Carbacyclisches phosphatidsäurederivat - Google Patents

Carbacyclisches phosphatidsäurederivat

Info

Publication number
DE60325609D1
DE60325609D1 DE60325609T DE60325609T DE60325609D1 DE 60325609 D1 DE60325609 D1 DE 60325609D1 DE 60325609 T DE60325609 T DE 60325609T DE 60325609 T DE60325609 T DE 60325609T DE 60325609 D1 DE60325609 D1 DE 60325609D1
Authority
DE
Germany
Prior art keywords
linear
carbon atoms
group containing
present
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60325609T
Other languages
English (en)
Inventor
Kimiko Murofushi
Mutsuko Mukai
Susumu Kobayashi
Hiromu Murofushi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60325609D1 publication Critical patent/DE60325609D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
DE60325609T 2002-06-11 2003-06-10 Carbacyclisches phosphatidsäurederivat Expired - Lifetime DE60325609D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002169743A JP4162927B2 (ja) 2002-06-11 2002-06-11 カルバ環状ホスファチジン酸誘導体
PCT/JP2003/007335 WO2003104246A1 (ja) 2002-06-11 2003-06-10 カルバ環状ホスファチジン酸誘導体

Publications (1)

Publication Number Publication Date
DE60325609D1 true DE60325609D1 (en) 2009-02-12

Family

ID=29727741

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60325609T Expired - Lifetime DE60325609D1 (en) 2002-06-11 2003-06-10 Carbacyclisches phosphatidsäurederivat

Country Status (7)

Country Link
US (1) US7550449B2 (de)
EP (1) EP1535926B1 (de)
JP (1) JP4162927B2 (de)
AT (1) ATE419258T1 (de)
DE (1) DE60325609D1 (de)
HK (1) HK1078586A1 (de)
WO (1) WO2003104246A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4815063B2 (ja) * 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び/又は生存の促進のための薬剤
CN101610775B (zh) 2006-12-28 2012-12-12 国立大学法人御茶水女子大学 含有环状磷脂酸衍生物的镇痛剂
US8686177B2 (en) * 2008-03-03 2014-04-01 Rxbio, Inc. LPA receptor agonists and antagonists
US9085593B2 (en) * 2011-11-11 2015-07-21 Sansho Co., Ltd. Therapeutic agent for arthrosis
SG11201406911RA (en) * 2012-04-27 2014-11-27 Sansho Co Hair-growing agent
EP2949329B1 (de) 2013-01-28 2019-05-01 Ochanomizu University Therapeutikum gegen demyelinisierende krankheit
TWI733108B (zh) 2014-08-12 2021-07-11 日商大塚化學股份有限公司 環狀膦酸鈉鹽之結晶及其製造方法
JPWO2021132297A1 (de) * 2019-12-23 2021-07-01
WO2022114058A1 (ja) 2020-11-26 2022-06-02 Sansho株式会社 肺線維症治療剤

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238965A (en) * 1991-05-31 1993-08-24 The Procter & Gamble Company Methods of using lysophosphatidic acids for regulating skin wrinkles
JP3195833B2 (ja) 1991-09-30 2001-08-06 きみ子 室伏 新規生理活性物質及びその製造法
JPH06228169A (ja) 1993-02-05 1994-08-16 Sagami Chem Res Center 1−o−アシルグリセロール2,3−ホスフェートの製造法
JPH07149772A (ja) 1993-11-26 1995-06-13 Sagami Chem Res Center タンパク質リン酸化酵素cの活性促進剤
JPH07258278A (ja) 1994-03-18 1995-10-09 Sagami Chem Res Center 1−O−アシルグリセロール−2,3−ホスフェート誘導体を有効成分とするDNAポリメラーゼαの阻害剤
JPH0925235A (ja) 1995-07-13 1997-01-28 Sagami Chem Res Center 1−o−アシルグリセロール−2,3−ホスフェート誘導体を有効成分とするがん転移抑制剤
DE19542305A1 (de) * 1995-11-14 1997-05-15 Hoechst Schering Agrevo Gmbh Triazolylmethyl-cyclophosphanoxide, ihre Verwendung als Herbizide oder Pflanzenwachstumsregulatoren und Verfahren zu ihrer Herstellung
AU3191599A (en) 1998-03-18 1999-10-11 Lxr Biotechnology Inc. Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof
US6150345A (en) 1998-08-10 2000-11-21 Regents Of The University Of California Methods for promoting survival of myelin producing cells
IL129178A0 (en) 1999-03-25 2000-02-17 Yeda Res & Dev Induction of nerve generation
IL129179A0 (en) 1999-03-25 2000-02-17 Yeda Res & Dev Cyclic glycerophosphates and analogs thereof
JP4836345B2 (ja) 2001-04-13 2011-12-14 きみ子 室伏 環状ホスファチジン酸誘導体を含む神経細胞の生存促進剤
JP4815063B2 (ja) 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び/又は生存の促進のための薬剤
EP1402894B1 (de) * 2001-05-21 2007-12-26 Kimiko Murofushi Krebsmetastasen-hemmer mit carbacyclischen phosphatidinsäurederivaten

Also Published As

Publication number Publication date
EP1535926B1 (de) 2008-12-31
US7550449B2 (en) 2009-06-23
WO2003104246A1 (ja) 2003-12-18
EP1535926A1 (de) 2005-06-01
ATE419258T1 (de) 2009-01-15
JP4162927B2 (ja) 2008-10-08
JP2004010582A (ja) 2004-01-15
EP1535926A4 (de) 2008-03-12
US20060122155A1 (en) 2006-06-08
HK1078586A1 (en) 2006-03-17

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