DE60324196D1 - Narcistatin-prodrugs - Google Patents

Narcistatin-prodrugs

Info

Publication number
DE60324196D1
DE60324196D1 DE60324196T DE60324196T DE60324196D1 DE 60324196 D1 DE60324196 D1 DE 60324196D1 DE 60324196 T DE60324196 T DE 60324196T DE 60324196 T DE60324196 T DE 60324196T DE 60324196 D1 DE60324196 D1 DE 60324196D1
Authority
DE
Germany
Prior art keywords
narcistatin
prodrugs
narcistatin prodrugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60324196T
Other languages
English (en)
Inventor
George R Pettit
Noeleen Melody
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arizona Board of Regents of University of Arizona
University of Arizona
Original Assignee
Arizona Board of Regents of University of Arizona
University of Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arizona Board of Regents of University of Arizona, University of Arizona filed Critical Arizona Board of Regents of University of Arizona
Application granted granted Critical
Publication of DE60324196D1 publication Critical patent/DE60324196D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60324196T 2002-12-09 2003-12-09 Narcistatin-prodrugs Expired - Lifetime DE60324196D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43221902P 2002-12-09 2002-12-09
PCT/US2003/039067 WO2004052298A2 (en) 2002-12-09 2003-12-09 Narcistatin prodrugs

Publications (1)

Publication Number Publication Date
DE60324196D1 true DE60324196D1 (de) 2008-11-27

Family

ID=32507871

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60324196T Expired - Lifetime DE60324196D1 (de) 2002-12-09 2003-12-09 Narcistatin-prodrugs

Country Status (4)

Country Link
US (2) US7462609B2 (de)
EP (2) EP1585750B1 (de)
DE (1) DE60324196D1 (de)
WO (1) WO2004052298A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7462609B2 (en) * 2002-12-09 2008-12-09 Arizona Board Of Regents Narcistatin prodrugs
US20050261246A1 (en) * 2004-03-05 2005-11-24 The Arizona Board Of Regents Methods for treating inflammatory and autoimmune diseases
AU2006204672A1 (en) * 2005-01-14 2006-07-20 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Synthesis of sodium narcistatin and related compounds
WO2006122723A1 (en) * 2005-05-19 2006-11-23 Vaecgene Biotech Gmbh Method for the prevention and/or treatment of autoimmune disease or allogeneic transplant rejections
FR2934266B1 (fr) 2008-07-28 2010-09-17 Pf Medicament Derives azotes de la pancratistatine
JP2013527849A (ja) * 2010-05-03 2013-07-04 ユニヴェルシテ・リブレ・ドゥ・ブリュッセル ヒガンバナ科イソカルボスチリル生成物の新規プロドラッグ及びその脳腫瘍を対象とした使用
WO2016130969A1 (en) 2015-02-13 2016-08-18 George Robert Pettit Silstatin compounds
US11629167B2 (en) 2017-11-09 2023-04-18 Arizona Board Of Regents On Behalf Of Arizona State University Betulastatin compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4985436A (en) * 1984-02-17 1991-01-15 Arizona Board Of Regents Composition of matter for inhibiting leukemias and sarcomas
US5529989A (en) 1995-01-09 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Pancratistatin prodrug
US5830850A (en) 1996-08-28 1998-11-03 Mount Sinai School Of Medicine Of The City Of New York Methods for the treatment of bone resorption disorders, including osteoporosis
JP3660072B2 (ja) 1996-09-26 2005-06-15 シャープ株式会社 光磁気記録媒体及びその記録方法並びに光磁気記録装置
JPH11255650A (ja) 1998-03-12 1999-09-21 Kanegafuchi Chem Ind Co Ltd アポトーシス抑制剤
US6538038B1 (en) 1999-02-18 2003-03-25 Oxigene, Inc. Compositions and methods for use in targeting vascular destruction
GB0122731D0 (en) 2001-09-20 2001-11-14 Univ Strathclyde Anti-inflammatory agent
US7462609B2 (en) * 2002-12-09 2008-12-09 Arizona Board Of Regents Narcistatin prodrugs

Also Published As

Publication number Publication date
WO2004052298A3 (en) 2004-09-30
EP1585750B1 (de) 2008-10-15
WO2004052298A2 (en) 2004-06-24
US20060135481A1 (en) 2006-06-22
US20090082569A1 (en) 2009-03-26
EP1585750A2 (de) 2005-10-19
EP1990346A2 (de) 2008-11-12
EP1990346A3 (de) 2009-02-18
US7994320B2 (en) 2011-08-09
US7462609B2 (en) 2008-12-09
EP1585750A4 (de) 2007-08-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition