DE60324160D1 - Verfahren und vorrichtung zur detektion von malignität-assoziierten veränderungen - Google Patents
Verfahren und vorrichtung zur detektion von malignität-assoziierten veränderungenInfo
- Publication number
- DE60324160D1 DE60324160D1 DE60324160T DE60324160T DE60324160D1 DE 60324160 D1 DE60324160 D1 DE 60324160D1 DE 60324160 T DE60324160 T DE 60324160T DE 60324160 T DE60324160 T DE 60324160T DE 60324160 D1 DE60324160 D1 DE 60324160D1
- Authority
- DE
- Germany
- Prior art keywords
- cancer
- detect
- associated tissues
- detecting
- malignity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 210000001519 tissue Anatomy 0.000 abstract 6
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 201000011510 cancer Diseases 0.000 abstract 3
- 206010006187 Breast cancer Diseases 0.000 abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 abstract 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 201000005202 lung cancer Diseases 0.000 abstract 2
- 208000020816 lung neoplasm Diseases 0.000 abstract 2
- 206010036790 Productive cough Diseases 0.000 abstract 1
- 210000005178 buccal mucosa Anatomy 0.000 abstract 1
- 238000004590 computer program Methods 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 230000036210 malignancy Effects 0.000 abstract 1
- 210000002445 nipple Anatomy 0.000 abstract 1
- 210000003802 sputum Anatomy 0.000 abstract 1
- 208000024794 sputum Diseases 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T5/00—Image enhancement or restoration
- G06T5/40—Image enhancement or restoration using histogram techniques
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T5/00—Image enhancement or restoration
- G06T5/90—Dynamic range modification of images or parts thereof
- G06T5/94—Dynamic range modification of images or parts thereof based on local image properties, e.g. for local contrast enhancement
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/698—Matching; Classification
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Quality & Reliability (AREA)
- Multimedia (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Molecular Biology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Image Processing (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Geophysics And Detection Of Objects (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Image Analysis (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/232,698 US7274809B2 (en) | 2002-08-29 | 2002-08-29 | Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer |
PCT/CA2003/001262 WO2004021260A1 (en) | 2002-08-29 | 2003-08-22 | A method and a system for detection of malignancy-associated changes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60324160D1 true DE60324160D1 (de) | 2008-11-27 |
Family
ID=31977067
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60324160T Expired - Lifetime DE60324160D1 (de) | 2002-08-29 | 2003-08-22 | Verfahren und vorrichtung zur detektion von malignität-assoziierten veränderungen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7274809B2 (de) |
EP (1) | EP1532573B1 (de) |
JP (1) | JP2005536752A (de) |
CN (1) | CN100380390C (de) |
AT (1) | ATE411565T1 (de) |
AU (1) | AU2003258417B2 (de) |
CA (1) | CA2496174C (de) |
DE (1) | DE60324160D1 (de) |
WO (1) | WO2004021260A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7153691B2 (en) * | 2002-11-13 | 2006-12-26 | G6 Science Corp. | Method of identifying and assessing DNA euchromatin in biological cells for detecting disease, monitoring wellness, assessing bio-activity, and screening pharmacological agents |
US7760927B2 (en) * | 2003-09-10 | 2010-07-20 | Bioimagene, Inc. | Method and system for digital image based tissue independent simultaneous nucleus cytoplasm and membrane quantitation |
DE10353785B4 (de) * | 2003-11-18 | 2006-05-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zur Erfassung von verschiedenen Zelltypen von Zellen in einer biologischen Probe |
US20060134731A1 (en) * | 2004-12-22 | 2006-06-22 | Louise Isenstein | Stain characterization for automated cytology |
US7817841B2 (en) | 2005-11-12 | 2010-10-19 | General Electric Company | Time-lapse cell cycle analysis of unstained nuclei |
EP1984737A2 (de) * | 2006-01-17 | 2008-10-29 | Cellumen, Inc. | Verfahren zur vorhersage von reaktionen biologischer systeme |
WO2007136724A2 (en) | 2006-05-17 | 2007-11-29 | Cellumen, Inc. | Method for automated tissue analysis |
US20100112602A1 (en) * | 2006-11-10 | 2010-05-06 | Taylor Lansing D | Protein-Protein Interaction Biosensors and Methods of Use Thereof |
US7835561B2 (en) * | 2007-05-18 | 2010-11-16 | Visiongate, Inc. | Method for image processing and reconstruction of images for optical tomography |
US7787112B2 (en) | 2007-10-22 | 2010-08-31 | Visiongate, Inc. | Depth of field extension for optical tomography |
US8143600B2 (en) | 2008-02-18 | 2012-03-27 | Visiongate, Inc. | 3D imaging of live cells with ultraviolet radiation |
US8090183B2 (en) | 2009-03-12 | 2012-01-03 | Visiongate, Inc. | Pattern noise correction for pseudo projections |
US8139833B2 (en) * | 2008-04-09 | 2012-03-20 | Boris Fain | Analyzing large data sets using a computer system |
US8254023B2 (en) * | 2009-02-23 | 2012-08-28 | Visiongate, Inc. | Optical tomography system with high-speed scanner |
US8155420B2 (en) | 2009-05-21 | 2012-04-10 | Visiongate, Inc | System and method for detecting poor quality in 3D reconstructions |
US8655035B2 (en) * | 2010-05-26 | 2014-02-18 | Nec Laboratories America, Inc. | Epithelial structure detector and related methods |
US8767069B2 (en) * | 2010-06-30 | 2014-07-01 | Luminex Corporation | Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution |
JP5693894B2 (ja) | 2010-08-26 | 2015-04-01 | 日本光電工業株式会社 | 細胞解析装置及び細胞解析方法 |
AU2012229102B2 (en) | 2011-03-17 | 2016-02-04 | Cernostics, Inc. | Systems and compositions for diagnosing Barrett's esophagus and methods of using the same |
MX346624B (es) * | 2011-09-13 | 2017-03-27 | Koninklijke Philips Nv | Sistema y metodo para la deteccion de anormalidades en una muestra biologica. |
JP5876359B2 (ja) * | 2012-03-30 | 2016-03-02 | シスメックス株式会社 | 癌化情報提供方法および癌化情報提供装置 |
JP6105061B2 (ja) * | 2012-06-15 | 2017-03-29 | ルミネックス コーポレーション | ガウシアンフィット残差選択基準を用いて画像を正規化するための装置、システム及び方法 |
JP6226663B2 (ja) * | 2013-09-19 | 2017-11-08 | 日本光電工業株式会社 | 細胞解析装置、および細胞解析方法 |
EP3786640B1 (de) | 2015-11-25 | 2022-08-24 | Cernostics, Inc. | Verfahren zum nachweis maligner transformation von barrett-esophagus |
US11069054B2 (en) | 2015-12-30 | 2021-07-20 | Visiongate, Inc. | System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy |
WO2018201072A2 (en) * | 2017-04-28 | 2018-11-01 | 4D Path Inc. | Apparatus, systems, and methods for rapid cancer detection |
CN109540890A (zh) * | 2018-11-27 | 2019-03-29 | 湖南品胜生物技术有限公司 | 一种基于细胞显微镜图像的dna定量分析方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3907437A (en) | 1973-04-26 | 1975-09-23 | Block Engineering | Cell classification system |
US4129854A (en) | 1976-10-25 | 1978-12-12 | Hitachi, Ltd. | Cell classification method |
US4453266A (en) * | 1980-04-21 | 1984-06-05 | Rush-Presbyterian-St. Luke's Medical Center | Method and apparatus for measuring mean cell volume of red blood cells |
US5485527A (en) | 1985-11-04 | 1996-01-16 | Becton Dickinson And Company | Apparatus and method for analyses of biological specimens |
US5016283A (en) | 1985-11-04 | 1991-05-14 | Cell Analysis Systems, Inc. | Methods and apparatus for immunoploidy analysis |
US4741043B1 (en) | 1985-11-04 | 1994-08-09 | Cell Analysis Systems Inc | Method of and apparatus for image analyses of biological specimens |
US5107422A (en) | 1989-10-02 | 1992-04-21 | Kamentsky Louis A | Method and apparatus for measuring multiple optical properties of biological specimens |
EP0445434B1 (de) | 1990-03-07 | 1997-11-05 | Cytyc Corporation | Thionin Färbungstechnik |
US5784162A (en) * | 1993-08-18 | 1998-07-21 | Applied Spectral Imaging Ltd. | Spectral bio-imaging methods for biological research, medical diagnostics and therapy |
US6026174A (en) * | 1992-10-14 | 2000-02-15 | Accumed International, Inc. | System and method for automatically detecting malignant cells and cells having malignancy-associated changes |
US5889881A (en) | 1992-10-14 | 1999-03-30 | Oncometrics Imaging Corp. | Method and apparatus for automatically detecting malignancy-associated changes |
US5942410A (en) | 1997-07-07 | 1999-08-24 | Oncometrics Imaging Corp. | Composition and method for staining cellular DNA, comprising thiazine derivative metabisulfite and methanol or ethanol |
CN1036118C (zh) * | 1992-12-29 | 1997-10-15 | 陈立奇 | 肿瘤图像诊断方法及系统 |
US5931780A (en) * | 1993-11-29 | 1999-08-03 | Arch Development Corporation | Method and system for the computerized radiographic analysis of bone |
US5978497A (en) | 1994-09-20 | 1999-11-02 | Neopath, Inc. | Apparatus for the identification of free-lying cells |
US5784193A (en) | 1996-06-28 | 1998-07-21 | Ferguson; Gary W. | Microscope slide with removable layer and method |
US5798266A (en) | 1996-08-27 | 1998-08-25 | K-Quay Enterprises, Llc | Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer |
US6221622B1 (en) | 1998-04-28 | 2001-04-24 | The Regents Of The University Of California | Method and kit for obtaining fluids and cellular material from breast ducts |
US6168779B1 (en) | 1997-09-16 | 2001-01-02 | The Regents Of The University Of California | Methods and kits for identifying ductal orifices |
AU1196799A (en) | 1997-10-24 | 1999-05-17 | Georgetown University | Evaluation of changes in breast cells using nipple aspirate fluid |
KR20030094281A (ko) * | 2001-03-12 | 2003-12-11 | 모노젠, 인크. | 세포에 기초한 질병상태의 검출 및 질병상태의 구별 |
-
2002
- 2002-08-29 US US10/232,698 patent/US7274809B2/en not_active Expired - Fee Related
-
2003
- 2003-08-22 AT AT03790586T patent/ATE411565T1/de not_active IP Right Cessation
- 2003-08-22 EP EP03790586A patent/EP1532573B1/de not_active Expired - Lifetime
- 2003-08-22 DE DE60324160T patent/DE60324160D1/de not_active Expired - Lifetime
- 2003-08-22 JP JP2004531324A patent/JP2005536752A/ja active Pending
- 2003-08-22 CN CNB038206471A patent/CN100380390C/zh not_active Expired - Fee Related
- 2003-08-22 WO PCT/CA2003/001262 patent/WO2004021260A1/en active Application Filing
- 2003-08-22 AU AU2003258417A patent/AU2003258417B2/en not_active Ceased
- 2003-08-22 CA CA2496174A patent/CA2496174C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN100380390C (zh) | 2008-04-09 |
US7274809B2 (en) | 2007-09-25 |
WO2004021260A1 (en) | 2004-03-11 |
EP1532573B1 (de) | 2008-10-15 |
JP2005536752A (ja) | 2005-12-02 |
CA2496174A1 (en) | 2004-03-11 |
US20040042646A1 (en) | 2004-03-04 |
CN1679047A (zh) | 2005-10-05 |
ATE411565T1 (de) | 2008-10-15 |
AU2003258417B2 (en) | 2008-04-10 |
AU2003258417A1 (en) | 2004-03-19 |
EP1532573A1 (de) | 2005-05-25 |
CA2496174C (en) | 2010-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R073 | Re-establishment requested |
Ref document number: 1532573 Country of ref document: EP |
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