DE60304836D1 - Verfahren zur konzentrationsbestimmung von adenoviruspartikeln - Google Patents

Verfahren zur konzentrationsbestimmung von adenoviruspartikeln

Info

Publication number
DE60304836D1
DE60304836D1 DE60304836T DE60304836T DE60304836D1 DE 60304836 D1 DE60304836 D1 DE 60304836D1 DE 60304836 T DE60304836 T DE 60304836T DE 60304836 T DE60304836 T DE 60304836T DE 60304836 D1 DE60304836 D1 DE 60304836D1
Authority
DE
Germany
Prior art keywords
adenovirus
absorptivity
accurate
virus
extinction coefficient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60304836T
Other languages
English (en)
Other versions
DE60304836T2 (de
Inventor
A Sweeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE60304836D1 publication Critical patent/DE60304836D1/de
Publication of DE60304836T2 publication Critical patent/DE60304836T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60304836T 2002-02-20 2003-02-14 Verfahren zur konzentrationsbestimmung von adenoviruspartikeln Expired - Fee Related DE60304836T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35833102P 2002-02-20 2002-02-20
US358331P 2002-02-20
PCT/US2003/004564 WO2003070891A2 (en) 2002-02-20 2003-02-14 Method of determining adenovirus particle concentration

Publications (2)

Publication Number Publication Date
DE60304836D1 true DE60304836D1 (de) 2006-06-01
DE60304836T2 DE60304836T2 (de) 2006-11-30

Family

ID=27757731

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60304836T Expired - Fee Related DE60304836T2 (de) 2002-02-20 2003-02-14 Verfahren zur konzentrationsbestimmung von adenoviruspartikeln

Country Status (9)

Country Link
US (1) US7316898B2 (de)
EP (1) EP1474533B1 (de)
JP (1) JP2005517942A (de)
AT (1) ATE324467T1 (de)
AU (1) AU2003213072A1 (de)
CA (1) CA2476447A1 (de)
DE (1) DE60304836T2 (de)
ES (1) ES2261921T3 (de)
WO (1) WO2003070891A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0524225D0 (en) * 2005-11-29 2006-01-04 Amersham Biosciences Ab Methods and apparatus for detecting and measuring the concentration of a substance in a solution
GB2460981B (en) * 2007-04-13 2011-11-09 Technologies Inc C Interactive variable pathlength device
US9663766B2 (en) 2015-07-24 2017-05-30 Bio-Rad Laboratories, Inc. Methods for purifying adenovirus vectors
WO2019241622A1 (en) * 2018-06-15 2019-12-19 Children's Hospital Medical Center Polypeptides, nucleic acid molecules, compositions, and related methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585362A (en) * 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
US5837520A (en) * 1995-03-07 1998-11-17 Canji, Inc. Method of purification of viral vectors
IL122614A0 (en) * 1995-06-15 1998-08-16 Introgene Bv Packaging systems for human recombinant adenovirus to be used in gene therapy
EP1707631A3 (de) * 1996-11-20 2006-12-27 Introgen Therapeutics, Inc. Ein verbessertes Verfahren zur Produktion und Reinigung von adenoviralen Vektoren
US6316185B1 (en) * 1999-09-29 2001-11-13 Mountain View Pharmaceuticals, Inc. Quantitation of viruses by light scattering

Also Published As

Publication number Publication date
EP1474533B1 (de) 2006-04-26
US20050095580A1 (en) 2005-05-05
CA2476447A1 (en) 2003-08-28
AU2003213072A8 (en) 2003-09-09
JP2005517942A (ja) 2005-06-16
ES2261921T3 (es) 2006-11-16
DE60304836T2 (de) 2006-11-30
ATE324467T1 (de) 2006-05-15
US7316898B2 (en) 2008-01-08
WO2003070891A2 (en) 2003-08-28
EP1474533A2 (de) 2004-11-10
WO2003070891A3 (en) 2003-12-04
EP1474533A4 (de) 2005-03-30
AU2003213072A1 (en) 2003-09-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee