DE60235544D1 - Stabile pulververabreichungsform zur inhalation - Google Patents
Stabile pulververabreichungsform zur inhalationInfo
- Publication number
- DE60235544D1 DE60235544D1 DE60235544T DE60235544T DE60235544D1 DE 60235544 D1 DE60235544 D1 DE 60235544D1 DE 60235544 T DE60235544 T DE 60235544T DE 60235544 T DE60235544 T DE 60235544T DE 60235544 D1 DE60235544 D1 DE 60235544D1
- Authority
- DE
- Germany
- Prior art keywords
- inhalation
- stable powder
- powder administration
- administration
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000843 powder Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- GUBGYTABKSRVRQ-CUHNMECISA-N D-Cellobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-CUHNMECISA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 1
- 229960000367 inositol Drugs 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/885,349 US6482429B1 (en) | 2001-06-20 | 2001-06-20 | Stable powder inhalation dosage formulation |
| PCT/US2002/018406 WO2003000240A2 (en) | 2001-06-20 | 2002-06-11 | Stable powder inhalation dosage formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60235544D1 true DE60235544D1 (de) | 2010-04-15 |
Family
ID=25386707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60235544T Expired - Lifetime DE60235544D1 (de) | 2001-06-20 | 2002-06-11 | Stabile pulververabreichungsform zur inhalation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6482429B1 (OSRAM) |
| EP (1) | EP1401409B1 (OSRAM) |
| JP (1) | JP4348179B2 (OSRAM) |
| AT (1) | ATE459346T1 (OSRAM) |
| CA (1) | CA2446221C (OSRAM) |
| DE (1) | DE60235544D1 (OSRAM) |
| ES (1) | ES2339751T3 (OSRAM) |
| MX (1) | MXPA03011517A (OSRAM) |
| WO (1) | WO2003000240A2 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9408499D0 (en) | 1994-04-28 | 1994-06-22 | Edwin Shirley Trucking Limited | A releasable joint for joining two construction elements of a transportable stage assembly |
| BR0107304A (pt) * | 2000-10-12 | 2002-08-13 | Boehringer Ingelheim Pharma | Pó para inalação contendo tiotrópio |
| US6620438B2 (en) * | 2001-03-08 | 2003-09-16 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists |
| US7776315B2 (en) * | 2000-10-31 | 2010-08-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and additional active ingredients |
| US20020193392A1 (en) * | 2000-11-13 | 2002-12-19 | Christel Schmelzer | Pharmaceutical compositions based on tiotropium salts of salts of salmeterol |
| US20100310477A1 (en) * | 2000-11-28 | 2010-12-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg. | Pharmaceutical compositions based on anticholingerics and additional active ingredients |
| US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
| DE10141377A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
| US6919325B2 (en) * | 2001-09-14 | 2005-07-19 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts |
| US7309707B2 (en) * | 2002-03-20 | 2007-12-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament |
| AU2003221531B2 (en) * | 2002-04-04 | 2008-10-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder formulations suitable for inhalation |
| US7763280B2 (en) * | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
| BRPI0416698A (pt) * | 2003-11-18 | 2007-01-30 | Shan Yansong | dispositivo de inalação agradável e sadio |
| CA2550811C (en) * | 2003-12-24 | 2012-05-01 | Jane Hirsh | Temperature-stable formulations, and methods of development thereof |
| US8349365B2 (en) * | 2005-09-27 | 2013-01-08 | Asahi Kasei Chemicals Corporation | Cellooligosaccharide-containing composition |
| US20100269819A1 (en) * | 2006-08-14 | 2010-10-28 | Sievers Robert E | Human Powered Dry Powder Inhaler and Dry Powder Inhaler Compositions |
| TR201007250A2 (tr) * | 2010-09-01 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Selobioz içeren formülasyon. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
| US5846516A (en) * | 1992-06-03 | 1998-12-08 | Alliance Pharmaceutial Corp. | Perfluoroalkylated amphiphilic phosphorus compounds: preparation and biomedical applications |
| SE9203743D0 (sv) * | 1992-12-11 | 1992-12-11 | Astra Ab | Efficient use |
| US5612053A (en) * | 1995-04-07 | 1997-03-18 | Edward Mendell Co., Inc. | Controlled release insufflation carrier for medicaments |
| WO2002015880A2 (en) * | 2000-08-25 | 2002-02-28 | Merck Patent Gmbh | Powdered mannitol and mannitol-containing compositions |
-
2001
- 2001-06-20 US US09/885,349 patent/US6482429B1/en not_active Expired - Lifetime
-
2002
- 2002-06-11 MX MXPA03011517A patent/MXPA03011517A/es active IP Right Grant
- 2002-06-11 AT AT02732063T patent/ATE459346T1/de active
- 2002-06-11 DE DE60235544T patent/DE60235544D1/de not_active Expired - Lifetime
- 2002-06-11 JP JP2003506887A patent/JP4348179B2/ja not_active Expired - Lifetime
- 2002-06-11 EP EP02732063A patent/EP1401409B1/en not_active Expired - Lifetime
- 2002-06-11 ES ES02732063T patent/ES2339751T3/es not_active Expired - Lifetime
- 2002-06-11 WO PCT/US2002/018406 patent/WO2003000240A2/en not_active Ceased
- 2002-06-11 CA CA2446221A patent/CA2446221C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1401409B1 (en) | 2010-03-03 |
| JP4348179B2 (ja) | 2009-10-21 |
| CA2446221A1 (en) | 2003-01-03 |
| ATE459346T1 (de) | 2010-03-15 |
| CA2446221C (en) | 2011-04-12 |
| JP2004534813A (ja) | 2004-11-18 |
| WO2003000240A2 (en) | 2003-01-03 |
| US6482429B1 (en) | 2002-11-19 |
| ES2339751T3 (es) | 2010-05-25 |
| EP1401409A2 (en) | 2004-03-31 |
| MXPA03011517A (es) | 2004-03-18 |
| WO2003000240A3 (en) | 2003-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |