DE60213626D1 - Verfahren zur Herstellung von glykosylierten Proteinen in Bryophyten Zellen - Google Patents

Verfahren zur Herstellung von glykosylierten Proteinen in Bryophyten Zellen

Info

Publication number
DE60213626D1
DE60213626D1 DE60213626T DE60213626T DE60213626D1 DE 60213626 D1 DE60213626 D1 DE 60213626D1 DE 60213626 T DE60213626 T DE 60213626T DE 60213626 T DE60213626 T DE 60213626T DE 60213626 D1 DE60213626 D1 DE 60213626D1
Authority
DE
Germany
Prior art keywords
glycosylated proteins
preparation
bryophyte
bryophyte cells
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60213626T
Other languages
English (en)
Other versions
DE60213626T2 (de
Inventor
Otmar Lienhart
Anna Dr Koprivova
Eva Dr Decker
Ralf Prof Dr Reski
Gilbert Dr Gorr
Christian Dr Stemmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eleva GmbH
Original Assignee
Greenovation Biotech GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greenovation Biotech GmbH filed Critical Greenovation Biotech GmbH
Application granted granted Critical
Publication of DE60213626D1 publication Critical patent/DE60213626D1/de
Publication of DE60213626T2 publication Critical patent/DE60213626T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60213626T 2002-12-20 2002-12-20 Verfahren zur Herstellung von glykosylierten Proteinen in Bryophyten Zellen Expired - Lifetime DE60213626T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02028536A EP1431394B1 (de) 2002-12-20 2002-12-20 Verfahren zur Herstellung von glykosylierten Proteinen in Bryophyten Zellen

Publications (2)

Publication Number Publication Date
DE60213626D1 true DE60213626D1 (de) 2006-09-14
DE60213626T2 DE60213626T2 (de) 2007-08-09

Family

ID=32338059

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60213626T Expired - Lifetime DE60213626T2 (de) 2002-12-20 2002-12-20 Verfahren zur Herstellung von glykosylierten Proteinen in Bryophyten Zellen

Country Status (8)

Country Link
EP (1) EP1431394B1 (de)
AT (1) ATE335084T1 (de)
CY (1) CY1106233T1 (de)
DE (1) DE60213626T2 (de)
DK (1) DK1431394T3 (de)
ES (1) ES2269595T3 (de)
PT (1) PT1431394E (de)
SI (1) SI1431394T1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8119406B2 (en) 2004-10-13 2012-02-21 Protalix Ltd. System and method for production of antibodies in plant cell culture
EP1905826A1 (de) * 2006-09-29 2008-04-02 Universität für Bodenkultur Wien Galactosyltransferase
EP1905825A1 (de) * 2006-09-29 2008-04-02 greenovation Biotech GmbH Galactosyltransferase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19947290A1 (de) * 1999-10-01 2001-04-19 Greenovation Pflanzenbiotechno Verfahren zur Herstellung proteinöser Substanzen
WO2001029242A2 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants

Also Published As

Publication number Publication date
DE60213626T2 (de) 2007-08-09
SI1431394T1 (sl) 2007-02-28
EP1431394A8 (de) 2005-07-06
CY1106233T1 (el) 2011-06-08
EP1431394B1 (de) 2006-08-02
PT1431394E (pt) 2006-12-29
ATE335084T1 (de) 2006-08-15
EP1431394A1 (de) 2004-06-23
ES2269595T3 (es) 2007-04-01
DK1431394T3 (da) 2006-12-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition