DE60205085D1 - Metal phthalocyanine analogues containing antibacterial compositions - Google Patents

Metal phthalocyanine analogues containing antibacterial compositions

Info

Publication number
DE60205085D1
DE60205085D1 DE60205085T DE60205085T DE60205085D1 DE 60205085 D1 DE60205085 D1 DE 60205085D1 DE 60205085 T DE60205085 T DE 60205085T DE 60205085 T DE60205085 T DE 60205085T DE 60205085 D1 DE60205085 D1 DE 60205085D1
Authority
DE
Germany
Prior art keywords
metal phthalocyanine
containing antibacterial
antibacterial compositions
analogues containing
phthalocyanine analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60205085T
Other languages
German (de)
Other versions
DE60205085T2 (en
Inventor
Gabrio Roncucci
Donata Dei
Giacomo Chiti
Lia Fantetti
Francesco Giuliani
Giulio Jori
Gian Maria Rossolini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molteni and C SpA
Original Assignee
Molteni and C SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molteni and C SpA filed Critical Molteni and C SpA
Application granted granted Critical
Publication of DE60205085D1 publication Critical patent/DE60205085D1/en
Publication of DE60205085T2 publication Critical patent/DE60205085T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/695—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/045—Special non-pigmentary uses, e.g. catalyst, photosensitisers of phthalocyanine dyes or pigments
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C09B47/04—Phthalocyanines abbreviation: Pc
    • C09B47/08—Preparation from other phthalocyanine compounds, e.g. cobaltphthalocyanineamine complex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds: <CHEM> having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivo/ex vivo applications, such as blood and blood derivatives sterilization. <IMAGE>
DE60205085T 2002-04-25 2002-04-25 Metal phthalocyanine analogues containing antibacterial compositions Expired - Lifetime DE60205085T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02009414A EP1356813B1 (en) 2002-04-25 2002-04-25 Antibacterial compositions comprising metal phthalocyanine analogues

Publications (2)

Publication Number Publication Date
DE60205085D1 true DE60205085D1 (en) 2005-08-25
DE60205085T2 DE60205085T2 (en) 2006-04-20

Family

ID=28685904

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60205085T Expired - Lifetime DE60205085T2 (en) 2002-04-25 2002-04-25 Metal phthalocyanine analogues containing antibacterial compositions

Country Status (14)

Country Link
US (1) US8664382B2 (en)
EP (1) EP1356813B1 (en)
JP (1) JP2005524692A (en)
CN (1) CN1332658C (en)
AT (1) ATE299705T1 (en)
AU (1) AU2003224100B2 (en)
CA (1) CA2484070C (en)
DE (1) DE60205085T2 (en)
DK (1) DK1356813T3 (en)
ES (1) ES2244694T3 (en)
IL (1) IL164801A0 (en)
SI (1) SI1356813T1 (en)
WO (1) WO2003090744A1 (en)
ZA (1) ZA200409452B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20050093A1 (en) 2005-05-05 2006-11-06 Molteni & C PROCESS FOR THE PREPARATION OF CHLORIDE OF PHYTALOCYANIC DERIVATIVES INCLUDING AT LEAST A AMMONIUM QUATERNARY GROUP
ITFI20050092A1 (en) 2005-05-05 2006-11-06 Molteni & C PHYTALOCIANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE
EP1904060B1 (en) * 2005-06-29 2011-06-01 L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio Societa' Per Azioni Use of phthalocyanine derivates for the non-photodynamic treatment of diseases
WO2007000472A1 (en) * 2005-06-29 2007-01-04 L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A. Self-sterilizing products
CN101212987B (en) * 2005-06-29 2011-02-02 阿利提兄弟有限公司L.莫太尼公司 Self-sterilizing products
CN102351864A (en) * 2011-07-20 2012-02-15 东北师范大学 Organic-functionalized non-aggregated phthalocyanine and preparation method thereof
CN102702210B (en) * 2012-06-01 2014-09-10 福州大学 Application of phthalocyanine metal complex containing piperazine ethyoxyl modified groups
CN103601728B (en) * 2013-11-25 2015-09-09 吉林大学 Solvable phthalocyanine derivates and for the preparation of organic and polymer solar photovoltaic device in water or water/alcohol
EP3193864A4 (en) * 2014-09-09 2018-04-25 Purepurge, Inc. Compositions for photodynamic control of infection
CN104610270B (en) * 2015-01-28 2017-03-08 吉林大学 Metal phthalocyanine is the embellishing cathode interface material of core and is used for preparing polymer photovoltaic cell
FI127163B (en) * 2016-11-17 2017-12-29 Tty-Säätiö photosensitizer
EP3553062A1 (en) * 2018-04-09 2019-10-16 Chemical Intelligence Limited Antimicrobial and anticancer cationic phthalocyanine compounds
EA202192435A1 (en) * 2019-03-06 2022-02-15 Мольтени Терапьютикс С.Р.Л. COMPOSITIONS FOR TOPICAL USE CONTAINING PHTHALOCyanINE PHOTO-SENSITIZERS
CN111072679B (en) * 2020-01-16 2022-07-01 福州大学 Non-peripheral quaternary ammonium group modified zinc phthalocyanine and preparation method and application thereof
CN112028901B (en) * 2020-10-16 2021-06-01 福州大学 Cetyl ammonium group modified phthalocyanine, preparation method thereof and application thereof as photodynamic medicament

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1007239B (en) * 1986-08-28 1990-03-21 切夫尔昂研究公司 With sequestrant to the hydrocarbon feed process for demetalizating
US5135717A (en) * 1986-12-24 1992-08-04 British Technology Group Usa Inc. Tetrabenztriazaporphyrin reagents and kits containing the same
IT1294325B1 (en) * 1997-08-14 1999-03-24 Molteni L E C Dei Fratelli Ali ZINC-PHTHALOCYANINS AND THEIR CONJUGATES, PREPARATION AND USE IN PHOTODYNAMIC THERAPY AND AS DIAGNOSTIC
DE60008354T2 (en) 2000-06-15 2004-12-09 L. Molteni & C. dei Fratelli Alitti Società di Esercizio S.p.A. Substituted metal phthalocyanines, their preparation and use
ES2244793T3 (en) 2001-03-21 2005-12-16 L. MOLTENI &amp; C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI NON CENTROSIMETRIC ANALOGS OF PHTALOCIANINE REPLACED BY METALS, ITS PREPARATION AND ITS USE IN PHOTODYNAMIC THERAPY AND IN VIVO DIAGNOSIS.
ITFI20020200A1 (en) * 2002-10-21 2004-04-22 Molteni & C Dei Flii Alitti S P A Societa L MESO-REPLACED PORPHYRINES.

Also Published As

Publication number Publication date
SI1356813T1 (en) 2006-02-28
US8664382B2 (en) 2014-03-04
EP1356813B1 (en) 2005-07-20
CA2484070A1 (en) 2003-11-06
CA2484070C (en) 2011-08-23
DE60205085T2 (en) 2006-04-20
WO2003090744A8 (en) 2004-03-18
ZA200409452B (en) 2005-12-28
EP1356813A1 (en) 2003-10-29
ES2244694T3 (en) 2005-12-16
AU2003224100A1 (en) 2003-11-10
AU2003224100B2 (en) 2006-10-05
US20050234032A1 (en) 2005-10-20
ATE299705T1 (en) 2005-08-15
CN1332658C (en) 2007-08-22
JP2005524692A (en) 2005-08-18
DK1356813T3 (en) 2005-12-05
CN1649584A (en) 2005-08-03
WO2003090744A1 (en) 2003-11-06
IL164801A0 (en) 2005-12-18

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