DE602008004350D1 - Verfahren zur umsetzung von c-terminalen peptidestern oder -säuren zu amiden unter verwendung von subtilisin in gegenwart von ammoniumsalzen - Google Patents

Verfahren zur umsetzung von c-terminalen peptidestern oder -säuren zu amiden unter verwendung von subtilisin in gegenwart von ammoniumsalzen

Info

Publication number
DE602008004350D1
DE602008004350D1 DE602008004350T DE602008004350T DE602008004350D1 DE 602008004350 D1 DE602008004350 D1 DE 602008004350D1 DE 602008004350 T DE602008004350 T DE 602008004350T DE 602008004350 T DE602008004350 T DE 602008004350T DE 602008004350 D1 DE602008004350 D1 DE 602008004350D1
Authority
DE
Germany
Prior art keywords
acids
terminal
subtilisin
peptidesteres
amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602008004350T
Other languages
English (en)
Inventor
Ivo Franci Eggen
Carmen G Boeriu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Publication of DE602008004350D1 publication Critical patent/DE602008004350D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE602008004350T 2007-06-25 2008-06-23 Verfahren zur umsetzung von c-terminalen peptidestern oder -säuren zu amiden unter verwendung von subtilisin in gegenwart von ammoniumsalzen Active DE602008004350D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07012410 2007-06-25
PCT/EP2008/057972 WO2009000814A1 (en) 2007-06-25 2008-06-23 Process for the conversion of c-terminal peptide esters or acids to amides employing subtilisin in the presence of ammonium salts

Publications (1)

Publication Number Publication Date
DE602008004350D1 true DE602008004350D1 (de) 2011-02-17

Family

ID=38596402

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602008004350T Active DE602008004350D1 (de) 2007-06-25 2008-06-23 Verfahren zur umsetzung von c-terminalen peptidestern oder -säuren zu amiden unter verwendung von subtilisin in gegenwart von ammoniumsalzen

Country Status (8)

Country Link
EP (1) EP2167673B1 (de)
AT (1) ATE494383T1 (de)
BR (1) BRPI0813378B1 (de)
DE (1) DE602008004350D1 (de)
DK (1) DK2167673T3 (de)
ES (1) ES2359121T3 (de)
MX (1) MX2009013623A (de)
WO (1) WO2009000814A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2634258A1 (de) * 2012-02-29 2013-09-04 Enzypep B.V. Enzymatische Synthese von Aminosäure und Peptid C-Endamiden

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150601A (en) * 2001-07-19 2010-06-30 Organon Nv Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component

Also Published As

Publication number Publication date
EP2167673A1 (de) 2010-03-31
MX2009013623A (es) 2010-01-20
EP2167673B1 (de) 2011-01-05
BRPI0813378A2 (pt) 2014-12-30
ES2359121T3 (es) 2011-05-18
DK2167673T3 (da) 2011-04-18
WO2009000814A1 (en) 2008-12-31
BRPI0813378B1 (pt) 2018-08-07
ATE494383T1 (de) 2011-01-15

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