DE602008004227D1 - Zweiwertiges metallionen-beladenes nano-transportsystem mit dendritischer architektur für die therapie - Google Patents

Zweiwertiges metallionen-beladenes nano-transportsystem mit dendritischer architektur für die therapie

Info

Publication number
DE602008004227D1
DE602008004227D1 DE602008004227T DE602008004227T DE602008004227D1 DE 602008004227 D1 DE602008004227 D1 DE 602008004227D1 DE 602008004227 T DE602008004227 T DE 602008004227T DE 602008004227 T DE602008004227 T DE 602008004227T DE 602008004227 D1 DE602008004227 D1 DE 602008004227D1
Authority
DE
Germany
Prior art keywords
ions
metallion
therapy
value
transport system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602008004227T
Other languages
English (en)
Inventor
Gerd Multhaup
Rainer Haag
Carina Treiber
Mohiuddin Abdul Quadir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Freie Universitaet Berlin
Original Assignee
Freie Universitaet Berlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Freie Universitaet Berlin filed Critical Freie Universitaet Berlin
Publication of DE602008004227D1 publication Critical patent/DE602008004227D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicinal Preparation (AREA)
DE602008004227T 2007-02-16 2008-02-15 Zweiwertiges metallionen-beladenes nano-transportsystem mit dendritischer architektur für die therapie Active DE602008004227D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07003315A EP1958624A1 (de) 2007-02-16 2007-02-16 Divalent Metallionen-geladenes Nano-Transportsystem mit dendritischer Architektur geeignet zur Therapie
PCT/EP2008/001176 WO2008098780A1 (en) 2007-02-16 2008-02-15 Divalent metal-ion loaded nano-transport system having a dendritic architecture useful for therapy

Publications (1)

Publication Number Publication Date
DE602008004227D1 true DE602008004227D1 (de) 2011-02-10

Family

ID=38198456

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602008004227T Active DE602008004227D1 (de) 2007-02-16 2008-02-15 Zweiwertiges metallionen-beladenes nano-transportsystem mit dendritischer architektur für die therapie

Country Status (7)

Country Link
US (1) US20100081773A1 (de)
EP (2) EP1958624A1 (de)
AT (1) ATE493120T1 (de)
DE (1) DE602008004227D1 (de)
DK (1) DK2131822T3 (de)
ES (1) ES2358860T3 (de)
WO (1) WO2008098780A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2647680T3 (en) 2012-04-03 2016-12-19 Thüringisches Inst Für Textil- Und Kunststoff-Forschung E V A process for the preparation of metalnanopartikeldispersioner and products thereof,
DE102015121366A1 (de) * 2015-12-08 2017-06-08 Dendropharm Gmbh Analgetische Zusammensetzungen mit Nanocarriern und ihre Verwendung
EP4149436A1 (de) * 2020-05-15 2023-03-22 Rutgers, the State University of New Jersey Zusammensetzungen und verfahren zur behandlung von wunden

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU532174B2 (en) * 1979-08-15 1983-09-22 Stephen James Beveridge Copper chelate compounds
US5938934A (en) * 1998-01-13 1999-08-17 Dow Corning Corporation Dendrimer-based nanoscopic sponges and metal composites
AU4978499A (en) * 1998-07-10 2000-02-01 Incyte Pharmaceuticals, Inc. Human transport protein homologs
GB2374008B (en) * 2001-04-04 2005-03-16 John Carter Pharmaceutical compositions comprising copper and zinc
EP1278061B1 (de) * 2001-07-19 2011-02-09 Sony Deutschland GmbH Chemische Sensoren aus Nanopartikel-Dendrimer-Komposit-Materialen
DE102004039875A1 (de) * 2004-08-17 2006-03-09 Universität Dortmund Nanotransportsystem mit dendritischer Architektur
JP2008545621A (ja) * 2005-04-20 2008-12-18 デンドリティック ナノテクノロジーズ，インコーポレイテッド 強化された拡大性と内部官能基性をもった樹枝状ポリマー

Also Published As

Publication number Publication date
EP2131822B1 (de) 2010-12-29
US20100081773A1 (en) 2010-04-01
WO2008098780A1 (en) 2008-08-21
EP1958624A1 (de) 2008-08-20
ES2358860T3 (es) 2011-05-16
EP2131822A1 (de) 2009-12-16
DK2131822T3 (da) 2011-04-04
ATE493120T1 (de) 2011-01-15

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