ATE493120T1 - Zweiwertiges metallionen-beladenes nano- transportsystem mit dendritischer architektur für die therapie - Google Patents

Zweiwertiges metallionen-beladenes nano- transportsystem mit dendritischer architektur für die therapie

Info

Publication number
ATE493120T1
ATE493120T1 AT08707738T AT08707738T ATE493120T1 AT E493120 T1 ATE493120 T1 AT E493120T1 AT 08707738 T AT08707738 T AT 08707738T AT 08707738 T AT08707738 T AT 08707738T AT E493120 T1 ATE493120 T1 AT E493120T1
Authority
AT
Austria
Prior art keywords
ions
therapy
dual
metal ion
transport system
Prior art date
Application number
AT08707738T
Other languages
English (en)
Inventor
Gerd Multhaup
Rainer Haag
Carina Treiber
Mohiuddin Quadir
Original Assignee
Univ Berlin Freie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Berlin Freie filed Critical Univ Berlin Freie
Application granted granted Critical
Publication of ATE493120T1 publication Critical patent/ATE493120T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
AT08707738T 2007-02-16 2008-02-15 Zweiwertiges metallionen-beladenes nano- transportsystem mit dendritischer architektur für die therapie ATE493120T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07003315A EP1958624A1 (de) 2007-02-16 2007-02-16 Divalent Metallionen-geladenes Nano-Transportsystem mit dendritischer Architektur geeignet zur Therapie
PCT/EP2008/001176 WO2008098780A1 (en) 2007-02-16 2008-02-15 Divalent metal-ion loaded nano-transport system having a dendritic architecture useful for therapy

Publications (1)

Publication Number Publication Date
ATE493120T1 true ATE493120T1 (de) 2011-01-15

Family

ID=38198456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08707738T ATE493120T1 (de) 2007-02-16 2008-02-15 Zweiwertiges metallionen-beladenes nano- transportsystem mit dendritischer architektur für die therapie

Country Status (7)

Country Link
US (1) US20100081773A1 (de)
EP (2) EP1958624A1 (de)
AT (1) ATE493120T1 (de)
DE (1) DE602008004227D1 (de)
DK (1) DK2131822T3 (de)
ES (1) ES2358860T3 (de)
WO (1) WO2008098780A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2647680B1 (de) 2012-04-03 2016-08-31 THÜRINGISCHES INSTITUT FÜR TEXTIL- UND KUNSTSTOFF-FORSCHUNG e.V. Verfahren zur Herstellung von Metallnanopartikeldispersionen und Produkte daraus
DE102015121366A1 (de) * 2015-12-08 2017-06-08 Dendropharm Gmbh Analgetische Zusammensetzungen mit Nanocarriern und ihre Verwendung
WO2021231702A1 (en) * 2020-05-15 2021-11-18 Rutgers, The State University Of New Jersey Compositions and methods for treating wounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU532174B2 (en) * 1979-08-15 1983-09-22 Stephen James Beveridge Copper chelate compounds
US5938934A (en) * 1998-01-13 1999-08-17 Dow Corning Corporation Dendrimer-based nanoscopic sponges and metal composites
CA2332307A1 (en) * 1998-07-10 2000-01-20 Incyte Pharmaceuticals, Inc. Human transport protein homologs
GB2374008B (en) * 2001-04-04 2005-03-16 John Carter Pharmaceutical compositions comprising copper and zinc
EP1278061B1 (de) * 2001-07-19 2011-02-09 Sony Deutschland GmbH Chemische Sensoren aus Nanopartikel-Dendrimer-Komposit-Materialen
DE102004039875A1 (de) * 2004-08-17 2006-03-09 Universität Dortmund Nanotransportsystem mit dendritischer Architektur
EP1877103A4 (de) * 2005-04-20 2010-11-03 Dendritic Nanotechnologies Inc Dendritische polymere mit verbesserter amplifikation und innerer funktionalität

Also Published As

Publication number Publication date
EP1958624A1 (de) 2008-08-20
DE602008004227D1 (de) 2011-02-10
US20100081773A1 (en) 2010-04-01
EP2131822B1 (de) 2010-12-29
EP2131822A1 (de) 2009-12-16
WO2008098780A1 (en) 2008-08-21
ES2358860T3 (es) 2011-05-16
DK2131822T3 (da) 2011-04-04

Similar Documents

Publication Publication Date Title
Zhou et al. Photothermally triggered copper payload release for cuproptosis‐promoted cancer synergistic therapy
Padovani et al. Advances in dental materials through nanotechnology: facts, perspectives and toxicological aspects
Melo et al. Nanotechnology-based restorative materials for dental caries management
JP2008150375A5 (de)
Cheng et al. Mn3O4 nanozyme for inflammatory bowel disease therapy
DK2125026T3 (en) FORMATIONS BASED ON bridged POLYCYCLIC COMPOUNDS FOR INHIBITION AND RELIEF OF DISEASES
US20100247611A1 (en) Titanium dioxide nanotubes for production and delivery of nitric oxide and methods for production thereof
NZ604029A (en) Methods of treating bladder cancer
LU92484I2 (fr) Paclitaxel formulé comme albumine liée à des nanoparticules
Zeng et al. Near-infrared light-controllable multifunction mesoporous polydopamine nanocomposites for promoting infected wound healing
PE20091265A1 (es) Nanoparticulas que contienen pioglitazona
ATE493120T1 (de) Zweiwertiges metallionen-beladenes nano- transportsystem mit dendritischer architektur für die therapie
Bhatti et al. Inorganic nanoparticles: toxic effects, mechanisms of cytotoxicity and phytochemical interactions
DE14189577T1 (de) Behandlung von Blasenentzündung mit hochdosiertem Chondroitinsulfat
DE60003217D1 (de) Inhalator zur behandlung der bronchien von pferden
ATE505194T1 (de) Neue therapeutische verwendungen von inecalcitol
Varaprasad et al. Antibiotic nanomaterials
Ghahremanloo et al. Antifungal effect of silver nanoparticles in acrylic resins
RU2020119061A (ru) Композиции на основе анизотропных наночастиц и способы их применения
RU2006109966A (ru) Препарат "янтастим-с" для терапии и профилактики инфекционных заболеваний животных
CN102715796A (zh) 多功能枕头套件
Shang et al. Cur@ ZIF-8@ BA nanomaterials with pH-responsive and photodynamic therapy properties promotes antimicrobial activity
Awais et al. A Review on the Recent Advancements on Therapeutic Effects of Metallic Ions in the Physiological Environments
Sharma et al. The Critical Roleplay of Iron Neurochemistry in Progression of Parkinson’s Disease
Manjubaashini et al. Healthcare and Biological Application of Graphene Quantum Dots

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2131822

Country of ref document: EP