DE602007008947D1 - 4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3-modulatoren - Google Patents

4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3-modulatoren

Info

Publication number
DE602007008947D1
DE602007008947D1 DE602007008947T DE602007008947T DE602007008947D1 DE 602007008947 D1 DE602007008947 D1 DE 602007008947D1 DE 602007008947 T DE602007008947 T DE 602007008947T DE 602007008947 T DE602007008947 T DE 602007008947T DE 602007008947 D1 DE602007008947 D1 DE 602007008947D1
Authority
DE
Germany
Prior art keywords
cüpyridine
modulatoren
als
sup
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007008947T
Other languages
English (en)
Inventor
Li Chen
Wayne Wen Lai
Matthias Nettekoven
Olivier Roche
Deye Zheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE602007008947D1 publication Critical patent/DE602007008947D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602007008947T 2006-12-08 2007-11-28 4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3-modulatoren Active DE602007008947D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125715 2006-12-08
PCT/EP2007/062930 WO2008068174A1 (en) 2006-12-08 2007-11-28 4,5,6,7-tetrahydro-thieno [2,3-c] pyridines as h3 modulators

Publications (1)

Publication Number Publication Date
DE602007008947D1 true DE602007008947D1 (en) 2010-10-14

Family

ID=38988092

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007008947T Active DE602007008947D1 (en) 2006-12-08 2007-11-28 4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3-modulatoren

Country Status (9)

Country Link
US (1) US20080146559A1 (de)
EP (1) EP2102215B1 (de)
JP (1) JP2010511657A (de)
CN (1) CN101541810A (de)
AT (1) ATE479691T1 (de)
CA (1) CA2670902A1 (de)
DE (1) DE602007008947D1 (de)
ES (1) ES2348964T3 (de)
WO (1) WO2008068174A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1998620B1 (de) * 2006-03-10 2011-01-12 Neurogen Corporation Piperazinyl-oxoalkyl-tetrahydroisochinoline und verwandte analoga
SG188212A1 (en) * 2010-09-02 2013-04-30 Suven Life Sciences Ltd Heterocyclyl compounds as histamine h3 receptor ligands

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247547A (en) 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
CA1328881C (en) 1984-12-21 1994-04-26 Pierre Barbier Process for the manufacture of oxetanones
CA1270837A (en) 1984-12-21 1990-06-26 Hoffmann-La Roche Limited Oxetanones
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
CA2035972C (en) 1990-02-23 2006-07-11 Martin Karpf Process for the preparation of oxetanones
US5274143A (en) 1991-07-23 1993-12-28 Hoffmann-La Roche Inc. Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione
US6004996A (en) 1997-02-05 1999-12-21 Hoffman-La Roche Inc. Tetrahydrolipstatin containing compositions
US6267952B1 (en) 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
WO2000009122A1 (en) 1998-08-14 2000-02-24 F. Hoffmann-La Roche Ag Pharmaceutical compositions containing lipase inhibitors
CN1152680C (zh) 1998-08-14 2004-06-09 霍夫曼-拉罗奇有限公司 含有脂酶抑制剂和壳聚糖的药物组合物

Also Published As

Publication number Publication date
US20080146559A1 (en) 2008-06-19
CN101541810A (zh) 2009-09-23
ATE479691T1 (de) 2010-09-15
WO2008068174A9 (en) 2009-06-18
EP2102215A1 (de) 2009-09-23
ES2348964T3 (es) 2010-12-17
CA2670902A1 (en) 2008-06-12
JP2010511657A (ja) 2010-04-15
WO2008068174A1 (en) 2008-06-12
EP2102215B1 (de) 2010-09-01

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